XPNPEP3 (NM_022098) Human Untagged Clone

CAT#: SC324449

XPNPEP3 (untagged)-Human X-prolyl aminopeptidase (aminopeptidase P) 3, putative (XPNPEP3), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: XPNPEP3
• Synonyms: APP3; ICP55; NPHPL1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_022098.2 GGCCCTGCAGGCGGTTGCGTTCCCCGTCGTTACCCTCTTTCTCTTCCCGACGCGTGAGTT
  AGGCCGTAATGCCTTGGCTGCTCTCAGCCCCCAAGCTGGTTCCCGCTGTAGCAAACGTCC
  GCGGCCTCTCAGGATGTATGTTGTGTTCACAGCGAAGGTACTCCCTTCAGCCTGTCCCAG
  AAAGGAGGATTCCAAACCGATACTTAGGCCAGCCCAGCCCCTTTACACACCCACACCTCC
  TCAGACCAGGGGAGGTAACTCCAGGACTATCTCAGGTGGAATATGCACTTCGCAGACACA
  AACTAATGTCTCTGATCCAGAAGGAAGCTCAAGGGCAGAGTGGGACAGACCAGACAGTGG
  TTGTGCTCTCCAACCCTACATACTACATGAGCAACGATATTCCCTATACTTTCCACCAAG
  ACAACAATTTCCTGTACCTATGTGGATTCCAAGAGCCTGATAGCATTCTTGTCCTTCAGA
  GCCTCCCTGGCAAACAATTACCATCACACAAAGCCATACTTTTTGTGCCTCGGCGAGATC
  CCAGTCGAGAACTTTGGGATGGTCCGCGATCTGGCACTGATGGAGCAATAGCTCTAACTG
  GAGTAGACGAAGCCTATACGCTAGAAGAATTTCAACATCTTCTACCAAAAATGAAAGCTG
  AGACGAACATGGTTTGGTATGACTGGATGAGGCCCTCACATGCACAGCTTCACTCTGACT
  ATATGCAGCCCCTGACTGAGGCCAAAGCCAAGAGCAAGAACAAGGTTCGGGGTGTTCAGC
  AGCTGATACAGCGCCTCCGGCTGATCAAGTCTCCTGCAGAAATTGAACGAATGCAGATTG
  CTGGGAAGCTGACATCACAGGCTTTCATAGAAACCATGTTCACCAGTAAAGCCCCTGTGG
  AAGAAGCCTTTCTTTATGCTAAGTTTGAATTTGAATGCCGGGCTCGTGGCGCAGACATTT
  TAGCCTATCCACCTGTGGTGGCTGGTGGTAATCGGTCAAACACTTTGCACTATGTGAAAA
  ATAATCAACTCATCAAGGATGGGGAAATGGTGCTTCTGGATGGAGGTTGTGAGTCTTCCT
  GCTATGTGAGTGACATCACACGTACGTGGCCAGTCAATGGCAGGTTCACCGCACCTCAGG
  CAGAACTCTATGAAGCCGTTCTAGAGATCCAAAGAGATTGTTTGGCCCTCTGCTTCCCTG
  GGACAAGCTTGGAGAACATCTACAGCATGATGCTGACCCTGATAGGACAGAAGCTTAAAG
  ACTTGGGGATCATGAAGAACATTAAGGAAAATAATGCCTTCAAGGCTGCTCGAAAATACT
  GTCCTCATCATGTTGGCCACTACCTCGGGATGGATGTCCATGACACTCCAGACATGCCCC
  GTTCCCTCCCTCTGCAGCCTGGGATGGTAATCACAATTGAGCCCGGCATTTATATTCCAG
  AGGATGACAAAGATGCCCCAGAGAAGTTTCGGGGTCTTGGTGTACGAATTGAGGATGATG
  TAGTGGTGACTCAGGACTCACCTTTCATCCTTTCTGCAGACTGTCCCAAAGAGATGAATG
  ACATTGAACAGATATGCAGCCAGGCTTCTTGACCTTCACTGCGGCCCACATGCACCTCAG
  GTTCAAAATGGGTGTCTTCTGGCAGCCCTGCACGTGTGCTTTCTGAGTGTCTCTGTGTGT
  GCATTAATATATGCATTCCATTTGGGAGCATAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022098.2 unedited
  GGACGATTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGGCCCTGCAG
  GCGGTTGCGTTCCCCGTCGTTACCCTCTTTCTCTTCCCGACGCGTGAGTTAGGCCGTAAT
  GCCTTGGCTGCTCTCAGCCCCCAAGCTGGTTCCCGCTGTAGCAAACGTCCGCGGCCTCTC
  AGGATGTATGTTGTGTTCACAGCGAAGGTACTCCCTTCAGCCTGTCCCAGAAAGGAGGAT
  TCCAAACCGATACTTAGGCCAGCCCAGCCCCTTTACACACCCACACCTCCTCAGACCAGG
  GGAGGTAACTCCAGGACTATCTCAGGTGGAATATGCACTTCGCAGACACAAACTAATGTC
  TCTGATCCAGAAGGAAGCTCAAGGGCAGAGTGGGACAGACCAGACAGTGGTTGTGCTCTC
  CAACCCTACATACTACATGAGCAACGATATTCCCTATACTTTCCACCAAGACAACAATTT
  CCTGTACCTATGTGGATTCCAAGAGCCTGATAGCATTCTTGTCCTTCAGAGCCTCCCTGG
  CAAACAATTACCATCACACAAAGCCATACTTTTTGTGCCTCGGCGAGATCCCAGTCGAGA
  ACTTTGGGATGGTCCGCGATCTGGCACTGATGGAGCAATAGCTCTAACTGGAGTAGACGA
  AGCCTATACGCTAGAAGAATTTCAACATCTTCTACCAAAAATGAAAGCTGAGACGAACAT
  GGTTTGGTATGACTGGATGAGGCCCTCACATGCACAGCTTCACTCTGACTATATGCAGCC
  CCTGACTGAGCCCAAGCCAAGAGCAGAACAAGGTTCGGGTTGTTCAGCAGCTGATACAGC
  GCTCGCTGATCAAGTTCTCCTGCAGATGACCGATGCAGAATGCTGGGAAGCTGACTCACA
  AGCTTCATAAGAACAATGTTCACCAGTAAGCCTGTGGAGAAGCCTTCCTTTATGCTAAGT
  TTGCGAT
• Restriction Sites: Please inquire
• ACCN: NM_022098
• ORF Size: 1524 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_022098.2, NP_071381.1
• RefSeq Size: 3060
• RefSeq ORF: 1524
• Locus ID: 63929
• Domains: Peptidase_M24, AMP_N
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known. [provided by RefSeq, Mar 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1, also known as APP3m). This isoform has been shown to be localized to the mitochondria (PMID:20179356). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.