gamma Catenin (JUP) (NM_002230) Human Untagged Clone

CAT#: SC324466

JUP (untagged)-Human junction plakoglobin (JUP), transcript variant 1


  "NM_002230" in other vectors (5)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol JUP
Synonyms CTNNG; DP3; DPIII; PDGB; PKGB
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_002230.1 GGCAGAAGCGCATGAGGCTGTGGGACTTGCCTTCCATTTGATTTCTGAATTGTGAAGGTG
CATGCTTTCTGGAGGCCTGCACAGACCTTTCCCACCCGCTTTCCTGAAAGAATTTGACAG
GGAAAGTGAGACCGCAGGAAGGCTTTTTGGGGGAAGGTTTCTTCAATGCTAGACTCTCTC
AGGCAGAGCTGCATCGGGCCCCCTGCCTTCCCTGCTCCCAATTTCCTGAGACCGCCCGCC
CCCACCCAGAATTGGGGATCTTGATCAGGTAGCCACGATGGAGGTGATGAACCTGATGGA
GCAGCCTATCAAGGTGACTGAGTGGCAGCAGACATACACCTACGACTCGGGTATCCACTC
GGGCGCCAACACCTGCGTGCCCTCCGTCAGCAGCAAGGGCATCATGGAGGAGGATGAGGC
CTGCGGGCGCCAGTACACGCTCAAGAAAACCACCACTTACACCCAGGGGGTGCCCCCCAG
CCAAGGTGACCTGGAGTACCAGATGTCCACAACAGCCAGGGCCAAACGGGTGCGGGAGGC
CATGTGCCCTGGTGTGTCAGGCGAGGACAGCTCGCTTCTGCTGGCCACCCAGGTGGAGGG
GCAGGCCACCAACCTGCAGCGACTGGCCGAGCCGTCCCAGCTGCTCAAGTCGGCCATTGT
GCATCTCATCAACTACCAGGATGATGCCGAGCTGGCCACTCGCGCCCTGCCCGAGCTCAC
CAAACTGCTCAACGACGAGGACCCGGTGGTGGTGACCAAGGCGGCCATGATTGTGAACCA
GCTGTCGAAGAAGGAGGCGTCGCGGCGGGCCCTGATGGGCTCGCCCCAGCTGGTGGCCGC
TGTCGTGCGTACCATGCAGAATACCAGCGACCTGGACACAGCCCGCTGCACCACCAGCAT
CCTGCACAACCTCTCCCACCACCGGGAGGGGCTGCTCGCCATCTTCAAGTCGGGTGGCAT
CCCTGCTCTGGTCCGCATGCTCAGCTCCCCTGTGGAGTCGGTCCTGTTCTATGCCATCAC
CACGCTGCACAACCTGCTCCTGTACCAGGAGGGCGCCAAGATGGCCGTGCGCCTGGCCGA
CGGGCTGCAAAAGATGGTGCCCCTGCTCAACAAGAACAACCCCAAGTTCCTGGCCATCAC
CACCGACTGCCTGCAGCTCCTGGCCTACGGCAACCAGGAGAGCAAGCTGATCATCCTGGC
CAATGGTGGGCCCCAGGCCCTCGTGCAGATCATGCGTAACTACAGTTATGAAAAGCTGCT
CTGGACCACCAGTCGTGTGCTCAAGGTGCTATCCGTGTGTCCCAGCAATAAGCCTGCCAT
TGTGGAGGCTGGTGGGATGCAGGCCCTGGGCAAGCACCTGACCAGCAACAGCCCCCGCCT
GGTGCAGAACTGCCTGTGGACCCTGCGCAACCTCTCAGATGTGGCCACCAAGCAGGAGGG
CCTGGAGAGTGTGCTGAAGATTCTGGTGAATCAGCTGAGTGTGGATGACGTCAACGTCCT
CACCTGTGCCACGGGCACACTCTCCAACCTGACATGCAACAACAGCAAGAACAAGACGCT
GGTGACACAGAACAGCGGTGTGGAGGCTCTCATCCATGCCATCCTGCGTGCTGGTGACAA
GGACGACATCACGGAGCCTGCCGTCTGCGCTCTGCGCCACCTCACTAGCCGCCACCCTGA
GGCCGAGATGGCCCAGAACTCTGTGCGTCTCAACTATGGCATCCCAGCCATCGTGAAGCT
GCTCAACCAGCCCAACCAGTGGCCACTGGTCAAGGCAACCATCGGCTTGATCAGGAATCT
GGCCCTGTGCCCAGCCAACCATGCCCCGCTGCAGGAGGCAGCGGTCATCCCCCGCCTCGT
CCAACTGCTGGTGAAGGCCCACCAGGATGCCCAGCGCCACGTAGCTGCAGGCACACAGCA
GCCCTACACGGATGGTGTGAGGATGGAGGAGATTGTGGAGGGCTGCACCGGAGCACTGCA
CATCCTCGCCCGGGACCCCATGAACCGCATGGAGATCTTCCGGCTCAACACCATTCCCCT
GTTTGTGCAGCTCCTGTACTCGTCGGTGGAGAACATCCAGCGCGTGGCTGCCGGGGTGCT
GTGTGAGCTGGCCCAGGACAAGGAGGCGGCCGACGCCATTGATGCAGAGGGGGCCTCGGC
CCCACTCATGGAGTTGCTGCACTCCCGCAACGAGGGCACTGCCACCTACGCTGCTGCCGT
CCTGTTCCGCATCTCCGAGGACAAGAACCCAGACTACCGGAAGCGCGTGTCCGTGGAGCT
CACCAACTCCCTCTTCAAGCATGACCCGGCTGCCTGGGAGGCTGCCCAGAGCATGATTCC
CATCAATGAGCCCTATGGAGATGACTTGGATGCCACCTACCGCCCCATGTACTCCAGCGA
TGTGCCCCTTGACCCGCTGGAGATGCACATGGACATGGATGGAGACTACCCCATCGACAC
CTACAGCGACGGCCTCAGGCCCCCGTACCCCACTGCAGACCACATGCTGGCCTAGGCGGC
CTGGCCCCAGTGCGGTTCCTCATCTGAGAGGCTCTCCGTGCAGGCGATGGGGCAAGACAG
AAAAGTGCCTGAGCTGGGGAAGCCGGGGTGTAACTTCCTGCTGCACCCTGCGCCTCCAGA
GGTCCTCCGTAGGGTCTTTCTTGGGATAGTGTTCTGCTCCTGCTTTTCTGTCCTGGGCAT
GGGTCCAGGGCCTGACACCCCCTCCAGGGCCCAGGTTCGAGACCCAAACCCCCAAAATCC
AAAACTTCTCTTGAAAAGTTCAGGGACCGTCCAGGGGAGATGGGGAGGAGATATGGAGTG
AGTCACCTGCTCCAGAAGATGCCAGCTTCTCTCTCCAGGGTGCTTAGTTGGCTTTGCCCA
CCCCTCACTCCCCAGGGAGCTCTGGGGACAGCTTCCTCACACCCCTGTCCCACCCACACA
GCTGCCCTAGCTGACCCCGAGAAGTGCTCTTGGCTGACCCCTCTGGTGTGTGGTGAGGGG
CTTTCTCTTCCCCTTCCTGTTTCAGACCCCCCCATTTCCCGCACATGGTGTGGGGGGCTG
GGGGAGGTCCAAGCAGAGTGTTTTATTATTATCGCTTTATGTTTTTGGTTATTGGTTTTT
TTGTATAGACCAAAGCAAAGAAAATAAAAATAACAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_002230
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002230.1, NP_002221.1
RefSeq Size 3490 bp
RefSeq ORF 2238 bp
Locus ID 3728
Cytogenetics 17q21.2
Domains Armadillo_seg
Protein Families Druggable Genome
Protein Pathways Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer
Gene Summary 'This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (1) lacks an alternate segment in the 5' UTR, compared to transcript variant 3. Variants 1-7 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

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