eIF2B epsilon (EIF2B5) (NM_003907) Human Untagged Clone

CAT#: SC324640

EIF2B5 (untagged)-Human eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa (EIF2B5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EIF2B5
• Synonyms: CACH; CLE; EIF-2B; EIF2Bepsilon; LVWM
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003907.2 TGCGTGCGGTGGCAGCTTCCTTGCGGAAGTGGTGACCGTGAGAGAAGAAGATGGCGGCCC
  CTGTAGTGGCGCCGCCTGGTGTGGTGGTTAGTCGGGCTAACAAGCGCAGCGGCGCGGGGC
  CGGGAGGCAGCGGTGGCGGGGGAGCCAGAGGGGCGGAGGAGGAACCGCCGCCGCCCCTAC
  AAGCAGTTCTGGTGGCCGATAGCTTCGATCGCCGCTTCTTCCCCATCTCCAAGGACCAGC
  CTCGGGTCCTCTTGCCCCTGGCCAATGTGGCATTAATTGACTACACTCTGGAATTCCTGA
  CTGCCACAGGTGTACAGGAAACATTTGTCTTTTGTTGCTGGAAAGCTGCTCAAATCAAAG
  AACATTTACTGAAGTCAAAGTGGTGCCGCCCTACATCTCTCAATGTGGTTCGAATAATTA
  CATCAGAGCTCTATCGATCACTGGGAGATGTCCTCCGTGATGTTGATGCCAAGGCTTTGG
  TGCGCTCTGACTTTCTTCTGGTGTATGGGGATGTCATCTCAAACATCAATATCACCAGAG
  CCCTTGAGGAACACAGGTTGAGACGGAAGCTAGAAAAAAATGTTTCTGTGATGACGATGA
  TCTTCAAGGAGTCATCCCCCAGCCACCCAACTCGTTGCCACGAAGACAATGTGGTAGTGG
  CTGTGGATAGTACCACAAACAGGGTTCTCCATTTTCAGAAGACCCAGGGTCTCCGGCGTT
  TTGCATTTCCTCTGAGCCTGTTTCAGGGCAGTAGTGATGGAGTGGAGGTTCGATATGATT
  TACTGGATTGTCATATCAGCATCTGTTCTCCTCAGGTGGCACAACTCTTTACAGACAACT
  TTGACTACCAAACTCGAGATGACTTTGTGCGAGGTCTCTTAGTGAATGAGGAGATCCTAG
  GGAACCAGATCCACATGCACGTAACAGCTAAGGAATATGGTGCCCGTGTCTCCAACCTAC
  ACATGTACTCAGCTGTCTGTGCTGACGTCATCCGCCGATGGGTCTACCCTCTCACCCCAG
  AGGCGAACTTCACTGACAGCACCACCCAGAGCTGCACTCATTCCCGGCACAACATCTACC
  GAGGGCCTGAGGTCAGCCTGGGCCATGGCAGCATCCTAGAGGAAAATGTGCTCCTGGGCT
  CTGGCACTGTCATTGGCAGCAATTGCTTTATCACCAACAGTGTCATTGGCCCCGGCTGCC
  ACATTGGTGATAACGTGGTGCTGGACCAGACCTACCTGTGGCAGGGTGTTCGAGTGGCGG
  CTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAGGAACGAGTGA
  CACTGAAACCACGCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGC
  CTGAGGGCTCGGTGATCTCTTTGCACCCTCCAGATGCAGAGGAAGATGAAGATGATGGCG
  AGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATGAAAGGTTACA
  ATCCAGCAGAAGTAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACA
  TGGAGGAAGAGGAGGAACTGCAGCAGAATCTGTGGGGACTCAAGATCAACATGGAAGAAG
  AGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGCCGGGGAGGCT
  CCCCTCAGATGGATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGG
  GCAAAGAGGAGAACATTTCTTGTGACAATCTCGTCCTGGAAATCAACTCTCTCAAGTATG
  CCTATAACGTAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTCCTGGAGTTCC
  CCCTGCAACAGATGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTC
  TGCTAAAGGCCTGGAGCCCTGTTTTTAGGAACTACATAAAGCGCGCAGCCGACCATTTGG
  AAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGTATTTCCATGG
  CCAAGGTACTGATGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCT
  GGTTCAGCCAAAGAGATACAACTGACAAGGGCCAGCAGTTGCGCAAGAATCAACAGCTGC
  AGAGGTTCATCCAGTGGCTAAAAGAGGCAGAAGAGGAGTCATCTGAAGATGACTGAAGTC
  ACACTGCCTGCTCCTTTGGGTGTGATTGAGTGCCCTCCTGGCTCCTGGGCTGGGACAAGT
  GAGGAACTAGCTGCAGAGGGATGAGTGACCACCATCCAGGCTGAGACTGAAAGGAGCAGA
  GGCTGGAACTACAGTATTCTTTCCCCTGCTAGCAACCATGTGCCTCCCATCCTGACTGTG
  GAGTTGGGATGTGGAAGTGGGGCTGGAACAAAGCTTCTGCCTAGGGAGGAGCTAAGCAGG
  CCCGGCAGTTGGAGGAAGGCCAGAGGAACAGCTTTGTGCTCCGGCTTTCCCTCAGGGAAC
  AGCAGAGAGCAGTTGGCTCTTTCTGCTGCTTGTATATGTTAATATTAAAAGAGAGTGGTG
  TAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003907.2 unedited
  AGTGCTAATTGTAACGACTACTATAGGGCGGCCGGAGAAGGGGGCGCGCCGGTACCGGCC
  CGGAATTCCCGGGAAAAGACGACCCACGCCTCCGTGCGTGCGGTGGCAGCTTCCTTGCGG
  AAGTGGTGACCGTGAGAGAAGAAGAGGCGGCCCCTGTAGTGGCGCCGCCTGGTGTGGTGG
  TTAGTCGGGCTAACAAGCGCAGCGGCGCGGGGCCGGGAGGCAGCGGTGGCGGGGGAGCCA
  GAGGGGCGGAGGAGGAACCGCCGCCGCCCCTACAAGCAGTTCTGGTGGCCGATAGCTTCG
  ATCGCCGCTTCTTCCCCATCTCCAAGGACCAGCCTCGGGTCCTCTTGCCCCGGGCCAATG
  TGGCATTAATTGACTACACTCTGGAATTCCTGACTGCCACAGGTGTACAGGAAATATTTG
  TCTTTTGTTGCTGGAAAGCTGCTCAAATCAAAGAACATTTACTGAAGTCAAAGTGGTGCC
  GCCCTACATCTCTCAATGTGGTTCGAATAATTACATCAGAGCTCTATCGATCACTGGGAG
  ATGTCCTCCGTGATGTTGATGCCAAGGCTTTTGGTGCGCTCTGACTTTCTTCTGGTGTAT
  GGTGATGTCATCTCAAACATCAATATCACCAGAGCCCTTGCGGAACACTAGGTTGAGACG
  GTAGCTAGAAAAAAAATGTTTCTGTGATGACGATGATCTTTAAGGAGTTATCCCCAGCCA
  CCCCACTCGTTGCCACTGAAACAATGTGTTAGTGGCTGTTGATAGTACCACAAACAGCGC
  CTCCTCCATTTTCACGAAAATCCAAAGTTTCCCGCCGTTTTGGCTTTTCCTCCTGAGCCT
  TGTTTTACGGACAAGAAGTGTCGGCGACG
• Restriction Sites: Please inquire
• ACCN: NM_003907
• ORF Size: 2166 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003907.2, NP_003898.2
• RefSeq Size: 2898
• RefSeq ORF: 2166
• Locus ID: 8893
• Gene Summary: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]