UGT1A10 (NM_019075) Human Untagged Clone

CAT#: SC324652

UGT1A10 (untagged)-Human UDP glucuronosyltransferase 1 family, polypeptide A10 (UGT1A10)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UGT1A10
• Synonyms: GNT1; hUG-BR1; UDPGT; UGT-1A; UGT-1J; UGT1; UGT1-01; UGT1-10; UGT1.1; UGT1.10; UGT1A; UGT1A1; UGT1J
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_019075.2 GTACTTCTTCCGCCTACTGTATCATAGCAGCTTAGAATCCCAGCTGCTGGCTCGGGCTGC
  AGTTCTCTCATGGCTCGCGCAGGGTGGACCAGCCCCGTTCCTTTATGTGTGTGTCTACTG
  CTGACCTGTGGCTTTGCCGAGGCAGGGAAGCTGCTGGTAGTGCCCATGGATGGGAGTCAC
  TGGTTCACCATGCAGTCGGTGGTGGAGAAACTTATCCTCAGGGGGCATGAGGTGGTTGTA
  GTCATGCCAGAGGTGAGTTGGCAACTGGAAAGATCACTGAATTGCACAGTGAAGACTTAC
  TCAACCTCGTACACTCTGGAAGATCAGAACCGGGAATTCATGGTTTTCGCCCATGCTCAA
  TGGAAAGCACAGGCACAAAGTATATTTTCTCTATTAATGAGTTCATCCAGTGGTTTTCTT
  GACTTATTTTTTTCGCATTGCAGGAGTTTGTTTAATGACCGAAAATTAGTAGAATACTTA
  AAGGAGAGTTCTTTTGATGCAGTGTTTCTGGATCCTTTTGATACCTGTGGCTTAATTGTT
  GCTAAATATTTCTCCCTCCCCTCTGTGGTCTTCACCAGGGGAATATTTTGCCACCATCTT
  GAAGAAGGTGCACAGTGCCCTGCTCCTCTTTCCTATGTCCCCAATGATCTCTTAGGGTTC
  TCAGATGCCATGACTTTCAAGGAGAGAGTATGGAACCACATCGTGCACTTGGAGGACCAT
  TTATTTTGCCAGTATCTTTTTAGAAATGCCCTAGAAATAGCCTCTGAAATTCTCCAAACC
  CCTGTCACGGCATATGATCTCTACAGTCACACATCAATTTGGTTGTTGCGAACGGACTTT
  GTTTTGGACTATCCCAAACCCGTGATGCCCAACATGATCTTCATTGGTGGTATCAACTGT
  CATCAGGGAAAGCCATTGCCTATGGAATTTGAAGCCTACATTAATGCTTCTGGAGAACAT
  GGAATTGTGGTTTTCTCTTTGGGATCAATGGTCTCAGAAATTCCAGAGAAGAAAGCTATG
  GCAATTGCTGATGCTTTGGGCAAAATCCCTCAGACAGTCCTGTGGCGGTACACTGGAACC
  CGACCATCGAATCTTGCGAACAACACGATACTTGTTAAGTGGCTACCCCAAAACGATCTG
  CTTGGTCACCCGATGACCCGTGCCTTTATCACCCATGCTGGTTCCCATGGTGTTTATGAA
  AGCATATGCAATGGCGTTCCCATGGTGATGATGCCCTTGTTTGGTGATCAGATGGACAAT
  GCAAAGCGCATGGAGACTAAGGGAGCTGGAGTGACCCTGAATGTTCTGGAAATGACTTCT
  GAAGATTTAGAAAATGCTCTAAAAGCAGTCATCAATGACAAAAGTTACAAGGAGAACATC
  ATGCGCCTCTCCAGCCTTCACAAGGACCGCCCGGTGGAGCCGCTGGACCTGGCCGTGTTC
  TGGGTGGAGTTTGTGATGAGGCACAAGGGCGCGCCACACCTGCGCCCCGCAGCCCACGAC
  CTCACCTGGTACCAGTACCATTCCTTGGACGTGATTGGTTTCCTCTTGGCCGTCGTGCTG
  ACAGTGGCCTTCATCACCTTTAAATGTTGTGCTTATGGCTACCGGAAATGCTTGGGGAAA
  AAAGGGCGAGTTAAGAAAGCCCACAAATCCAAGACCCATTGAGAAGTGGGTGGGAAATAA
  GGTAAAATTTTGAACCATTCCCTAGTCATTTCCAAACTTGAAAACAGAATCAGTGTTAAA
  TTCATTTTATTCTTATTAAGGAAATACTTTGCATAAATTAATCAGCCCCAGAGTGCTTTA
  AAAAAATTCTCTTAAATAAAAATAATAGACTCGCTAGTCAGTAAAGATATTTGAATATGT
  ATCGTGCCCCCTCCGGTGTCTTTGATCAGGATGACATGTGCCATTTTTCAGAGGACGTGC
  AGACAGGCTGGCATTCTAGATTACTTTTCTTACTCTGAAACATGGCCTGTTTGGGAGTGC
  GGGATTCAAAGGTGGTCCCACCGCTGCCCCTACTGCAAATGGCAGTTTTAATCTTATCTT
  TTGGCTTCTGCAGATGGTTGCAATTGATCCTTAACCAATAATGGTCAGTCCTCATCTCTG
  TCCTGCTTCATAGGTGCCACCTTGTGTGTTTAAAGAAGGGAAGCTTTGTACCTTTAGAGT
  GTAGGTGAAATGAATGAATGGCTTGGAGTGCACTGAGAACAGCATATGATTTCTTGCTTT
  GGGGAAAAAGAATGATGCTATGAAATTGGTGGGTGGTGTATTTGAGAAGATAATCATTGC
  TTATGTCAAATGGAGCTGAATTTGATAAAAACCCAAAATACAGCTATGAAGTGCTGGGCA
  AGTTTACTTTTTTTCTGATGTTTCCTACAACTAAAAATAAATTAATAAATTTATATAAAT
  TCTATTTAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_019075.2 unedited
  GGCGATTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATATCGTCGACCCACGCGTCCGGTACTTCTTCCGCCTACTGTATCATA
  GCAGCTTAGAATCCCAGCTGCTGGCTCGGGCTGCAGTTCTCTCATGGCTCGCGCAGGGTG
  GACCAGCCCCGTTCCTTTATGTGTGTGTCTACTGCTGACCTGTGGCTTTGCCGAGGCAGG
  GAAGCTGCTGGTAGTGCCCATGGATGGGAGTCACTGGTTCACCATGCAGTCGGTGGTGGA
  GAAACTTATCCTCAGGGGGCATGAGGTGGTTGTAGTCATGCCAGAGGTGAGTTGGCAACT
  GGAAAGATCACTGAATTGCACAGTGAAGACTTACTCAACCTCGTACACTCTGGAAGATCA
  GAACCGGGAATTCATGGTTTTCGCCCATGCTCAATGGAAAGCACAGGCACAAAGTATATT
  TTCTCTATTAATGAGTTCATCCAGTGGTTTTCTTGACTTATTTTTTTCGCATTGCAGGAG
  TTTGTTTAATGACCGAAAATTAGTAGAATACTTAAAGGAGAGTTCTTTTGATGCAGTGTT
  TCTGGATCCTTTTGATACCTGTGGCTTAATTGTTGCTAAATATTTCTCCCTCCCCTCTGT
  GGTCTTCACCAGGGGAATATTTTGCCACCATCTTGAAGAAGGTGCACAGTGCCCTGCTCC
  TCTTTCCTATGTCCCCAATGATCTCTTAGGGTTCTCAGATGCCATGACTTTCAAGGAGAG
  AGTATGGAACCACATCGTGCACTTGGAGGACCATTTATTTTGCCAGTATTCTTTTAGAAT
  GCCCTAAGAAATAGCCTTCTGAAATCTCCAACCCTGTCACGGCATATGATTCTCTACAGT
  CACACATCAATTTGTTGTTGCACGAACTTTGTTTGGAACTAATTCCAAACCGTGGTTGCC
  CACCATGT
• Restriction Sites: Please inquire
• ACCN: NM_019075
• ORF Size: 1593 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_019075.2, NP_061948.1
• RefSeq Size: 2399
• RefSeq ORF: 1593
• Locus ID: 54575
• Protein Families: Transmembrane
• Protein Pathways: Androgen and estrogen metabolism, Ascorbate and aldarate metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism, Retinol metabolism, Starch and sucrose metabolism
• Gene Summary: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines. [provided by RefSeq, Jul 2008]