SKIP (INPP5K) (NM_001135642) Human Untagged Clone

CAT#: SC325008

INPP5K (untagged)-Human inositol polyphosphate-5-phosphatase K (INPP5K), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: INPP5K
• Synonyms: MDCCAID; PPS; SKIP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001135642, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGATGTGCTTTCCCCTCTGAGCTTCATCAAGGTCTCCCATGTCCGTATGCAGGGGATCCTCTTACTGG
  TCTTTGCCAAGTATCAGCATTTGCCCTATATCCAGATTCTGTCTACTAAATCCACCCCCACTGGCCTGTT
  TGGGTACTGGGGGAACAAAGGTGGAGTCAACATCTGCCTGAAGCTTTATGGCTACTATGTCAGCATCATC
  AACTGCCACCTGCCTCCCCACATTTCCAACAATTACCAGCGGCTGGAGCACTTTGACCGGATCCTGGAGA
  TGCAGAATTGTGAGGGGCGAGACATCCCAAACATCCTGGACCACGACCTCATTATCTGGTTTGGAGACAT
  GAACTTTCGGATCGAGGACTTTGGGTTGCACTTTGTTCGGGAATCCATTAAAAATCGGTGCTACGGTGGC
  CTGTGGGAGAAGGACCAGCTCAGCATTGCCAAGAAACATGACCCGCTGCTCCGGGAGTTCCAGGAGGGCC
  GCCTACTCTTCCCGCCCACCTACAAGTTTGATAGGAACTCCAACGACTATGACACCAGTGAGAAAAAACG
  CAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGCAGCCCTGTGCTGGCCCCGACACTCCC
  ATACCGCCGGCGTCACACTTCTCCTTGTCTCTGAGGGGCTACAGCAGCCACATGACGTACGGCATCAGCG
  ACCACAAGCCTGTCTCCGGCACGTTCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCT
  GATGCCCGAGGACCTGTGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCC
  AGCAGCCCGTGGGACTGGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAATGACTACGTGTCCTATG
  CCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACATCGACATCAGCAATAT
  CCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACAGTCTGCGTTCTGTGGTGGGGATAAGC
  AGACCCTTCCAGATCCCGCCTGGCTCCTTGAGGGAGGACCCACTGGGTGAAGCACAGCCACAGATCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001135642
• ORF Size: 1119 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001135642.1, NP_001129114.1
• RefSeq Size: 3391
• RefSeq ORF: 1119
• Locus ID: 51763
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Inositol phosphate metabolism, Insulin signaling pathway, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (3) has an additional segment in its 5' end, as compared to variant 1. The resulting isoform, isoform 2, has a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode the same isoform, isoform 2.