HRH2 (NM_001131055) Human Untagged Clone

CAT#: SC325046

HRH2 (untagged)-Human histamine receptor H2 (HRH2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HRH2
• Synonyms: H2R; HH2R
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001131055 edited
  TGGCATAGTTGTCACATTGGGAGCAGAGAAGAAGCAACCAGGGGCCCTGATCAGGGGACT
  GAGCCGTAGAGTCCCAGGATGGCACCCAATGGCACAGCCTCTTCCTTTTGCCTGGACTCT
  ACCGCATGCAAGATCACCATCACCGTGGTCCTTGCGGTCCTCATCCTCATCACCGTTGCT
  GGCAATGTGGTCGTCTGTCTGGCCGTGGGCTTGAACCGCCGGCTCCGCAACCTGACCAAT
  TGTTTCATCGTGTCCTTGGCTATCACTGACCTGCTCCTCGGCCTCCTGGTGCTGCCCTTC
  TCTGCCATCTACCAGCTGTCCTGCAAGTGGAGCTTTGGCAAGGTCTTCTGCAATATCTAC
  ACCAGCCTGGATGTGATGCTCTGCACAGCCTCCATTCTTAACCTCTTCATGATCAGCCTC
  GACCGGTACTGCGCTGTCATGGACCCACTGCGGTACCCTGTGCTGGTCACCCCAGTTCGG
  GTCGCCATCTCTCTGGTCTTAATTTGGGTCATCTCCATTACCCTGTCCTTTCTGTCTATC
  CACCTGGGGTGGAACAGCAGGAACGAGACCAGCAAGGGCAATCATACCACCTCTAAGTGC
  AAAGTCCAGGTCAATGAAGTGTACGGGCTGGTGGATGGGCTGGTCACCTTCTACCTCCCG
  CTACTGATCATGTGCATCACCTACTACCGCATCTTCAAGGTCGCCCGGGATCAGGCCAAG
  AGGATCAATCACATTAGCTCCTGGAAGGCAGCCACCATCAGGGAGCACAAAGCCACAGTG
  ACACTGGCCGCCGTCATGGGGGCCTTCATCATCTGCTGGTTTCCCTACTTCACCGCGTTT
  GTGTACCGTGGGCTGAGAGGGGATGATGCCATCAATGAGGTGTTAGAAGCCATCGTTCTG
  TGGCTGGGCTATGCCAACTCAGCCCTGAACCCCATCCTGTATGCTGCGCTGAACAGAGAC
  TTCCGCACCGGGTACCAACAGCTCTTCTGCTGCAGGCTGGCCAACCGCAACTCCCACAAA
  ACTTCTCTGAGGTCCAACGCCTCTCAGCTGTCCAGGACCCAAAGCCGAGAACCCAGGCAA
  CAGGAAGAGAAACCCCTGAAGCTCCAGGTGTGGAGTGGGACAGAAGTCACGGCCCCCCAG
  GGAGCCACAGACAGACCATGGCTTTGCCTTCCAGAATGCTGGTCTGTGGAACTGACCCAT
  TCATTCATTCATTTGTTCATTCATTCATTTGCAAACATTCATCCAATTCCCACCACATGC
  CAGGAATTATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001131055
• Insert Size: 1300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001131055.1.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001131055.1, NP_001124527.1
• RefSeq Size: 2624 bp
• RefSeq ORF: 1194 bp
• Locus ID: 3274
• Cytogenetics: 5q35.2
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: 'Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]'
  Transcript Variant: This variant (1) consists of three exons and encodes the longer isoform (1).