ITPK1 (NM_001142593) Human Untagged Clone

CAT#: SC325066

ITPK1 (untagged)-Human inositol-tetrakisphosphate 1-kinase (ITPK1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ITPK1
• Synonyms: ITRPK1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001142593, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAGACCTTTCTGAAAGGGAAGAGAGTTGGCTACTGGCTGAGCGAGAAGAAAATCAAGAAGCTGAATT
  TCCAGGCCTTCGCCGAGCTGTGCAGGAAGCGAGGGATGGAGGTTGTGCAGCTGAACCTTAGCCGGCCGAT
  CGAGGAGCAGGGCCCCCTGGACGTCATCATCCACAAGCTGACTGACGTCATCCTTGAAGCCGACCAGAAT
  GATAGCCAGTCCCTGGAGCTGGTGCACAGGTTCCAGGAGTACATCGATGCCCACCCTGAGACCATCGTCC
  TGGACCCGCTCCCTGCCATCAGAACCCTGCTTGACCGCTCCAAGTCCTATGAGCTCATCCGGAAGATTGA
  GGCCTACATGGAAGACGACAGGATCTGCTCGCCACCCTTCATGGAGCTCACGAGCCTGTGCGGGGATGAC
  ACCATGCGGCTGCTGGAGAAGAACGGCTTGACTTTCCCATTCATTTGCAAAACCAGAGTGGCTCATGGCA
  CCAACTCTCACGAGATGGCTATCGTGTTCAACCAGGAGGGCCTGAACGCCATCCAGCCACCCTGCGTGGT
  CCAGAATTTCATCAACCACAACGCCGTCCTGTACAAGGTGTTCGTGGTTGGCGAGTCCTACACCGTGGTC
  CAGAGGCCCTCACTCAAGAACTTCTCCGCAGGCACATCAGACCGTGAGTCCATCTTCTTCAACAGCCACA
  ACGTGTCAAAGCCGGAGTCGTCATCGGTCCTGACGGAGCTGGACAAGATCGAGGGCGTGTTCGAGCGGCC
  GAGCGACGAGGTCATCCGGGAGCTCTCCCGGGCCCTGCGGCAGGCACTGGGCGTGTCACTCTTCGGCATC
  GACATCATCATCAACAACCAGACAGGGCAGCACGCCGTCATTGACATCAATGCCTTCCCAGGCTACGAGG
  GCGTGAGCGAGTTCTTCACAGACCTCCTGAACCACATCGCCACTGTCCTGCAGGGCCAGAGCACAGCCAT
  GGCAGCCACAGGGGACGTGGCCCTGCTGAGGCACAGCAAGCTTCTGGCCGAGCCGGCGGGCGGCCTGGTG
  GGCGAGCGGACATGCAGCGCCAGCCCCGGCTGCTGCGGCAGCATGATGGGCCAGGACGCGCCCTGGAAGG
  CTGAGGCCGACGCGGGCGGCACCGCCAAGCTGCCGCACCAGAGACTCGGCTGCAACGCCGGCGTGTCGCC
  CAGCTTCCAGCAGCATTGTGTGGCCTCCCTGGCCACCAAGGCCTCCTCCCAGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001142593
• ORF Size: 1245 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001142593.2, NP_001136065.1
• RefSeq Size: 3265
• RefSeq ORF: 1245
• Locus ID: 3705
• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X. [provided by RefSeq, Jul 2016]
  Transcript Variant: This variant (2) uses an alternate splice pattern in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a).