PRMT3 (NM_001145167) Human Untagged Clone

CAT#: SC325100

PRMT3 (untagged)-Human protein arginine methyltransferase 3 (PRMT3), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRMT3
• Synonyms: HRMT1L3
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001145167, the custom clone sequence may differ by one or more nucleotides
  ATGGTTCATAAACATGGACTTGAATTTTATGGATACATTAAGCTAATAAATTTTATTAGA
  CTTAAGAATCCTACAGTTGAGTACATGAATTCCATATACAACCCAGTGCCTTGGGAGAAA
  GAAGAGTATTTGAAGCCAGTATTAGAAGATGACCTTTTACTTCAATTTGATGTAGAAGAT
  CTTTATGAACCGGTGTCAGTACCCTTCTCATACCCCAATGGACTCAGTGAAAATACATCT
  GTTGTTGAAAAATTGAAACATATGGAAGCCAGGGCACTGTCTGCTGAAGCCGCATTGGCC
  AGAGCACGTGAGGATCTGCAAAAAATGAAACAATTTGCTCAGGATTTTGTGATGCACACA
  GATGTCAGAACCTGCTCGTCATCTACTAGTGTCATTGCGGACCTCCAGGAGGATGAGGAT
  GGTGTTTATTTCAGCTCATACGGGCATTATGGGATACATGAAGAAATGCTAAAGGACAAA
  ATACGAACAGAAAGCTACCGAGATTTCATATACCAAAATCCACATATCTTCAAAGACAAG
  GTAGTTTTGGATGTTGGGTGTGGAACTGGAATTCTCTCTATGTTTGCTGCTAAAGCTGGG
  GCGAAGAAGGTTCTTGGAGTTGATCAATCTGAAATACTTTACCAGGCAATGGATATTATA
  AGACTAAATAAACTTGAAGATACTATTACACTAATTAAAGGAAAGATTGAAGAAGTTCAT
  CTTCCTGTAGAAAAAGTAGATGTTATCATATCTGAGTGGATGGGCTATTTTCTTCTGTTT
  GAGTCTATGTTAGATTCTGTCCTTTATGCAAAGAACAAATACTTGGCAAAAGGAGGCTCG
  GTCTACCCTGACATTTGCACTATCAGCCTTGTAGCAGTGAGTGATGTGAATAAACATGCT
  GATAGAATTGCTTTTTGGGATGATGTCTATGGCTTCAAGATGTCCTGCATGAAGAAAGCA
  GTTATTCCAGAAGCTGTTGTGGAAGTTTTAGATCCGAAGACTCTTATTTCAGAACCTTGT
  GGTATTAAGCATATAGATTGCCATACGACGTCTATCTCAGATTTGGAATTTTCATCAGAT
  TTTACCCTGAAAATCACAAGGACATCCATGTGCACGGCAATTGCTGGCTACTTTGATATA
  TATTTTGAGAAGAATTGCCACAACAGGGTCGTGTTCTCTACGGGCCCTCAGAGCACCAAA
  ACACACTGGAAACAAACAGTATTTCTACTGGAAAAACCATTTTCAGTTAAAGCAGGTGAA
  GCCTTGAAAGGAAAGGTCACAGTTCACAAGAATAAGAAAGATCCACGTTCTCTCACCGTG
  ACCCTCACGTTGAATAATTCAACTCAAACTTATGGTCTCCAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001145167
• ORF Size: 1365 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001145167.1, NP_001138639.1
• RefSeq Size: 2607
• RefSeq ORF: 1365
• Locus ID: 10196
• Protein Families: Druggable Genome
• Gene Summary: This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (3) is missing a coding exon at the 5' end compared to transcript variant 1. This results in translation initiation from an in-frame downstream AUG by leaky scanning, and a shorter isoform (3) with a truncated N-terminus compared to isoform 1.