WDR79 (WRAP53) (NM_001143990) Human Untagged Clone

CAT#: SC325186

WRAP53 (untagged)-Human WD repeat containing, antisense to TP53 (WRAP53), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WRAP53
• Synonyms: DKCB3; TCAB1; WDR79
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001143990 edited
  AAAGAATTGGCGTCCGCTGTTCGCCTCTCCTCCCGGGAGTCTTCTCCTACTCCCAGAAGA
  GGAGGGAAGCACAGTATGAAGACTTTGGAGACTCAACCGTTAGCTCCGGACTGCTGTCCT
  TCAGACCAGGACCCAGCTCCAGCCCATCCTTCTCCCCACGCTTCCCCGATGAATAAAAAT
  GCGGACTCTGAACTGATGCCACCGCCTCCCGAAAGGGGGGATCCGCCCCGGTTGTCCCCA
  GATCCTGTGGCTGGCTCAGCTGTGTCCCAGGAGCTACGGGAGGGGGACCCAGTTTCTCTC
  TCCACTCCCCTGGAAACAGAGTTTGGTTCCCCTAGTGAGTTGAGTCCTCGAATCGAGGAG
  CAAGAACTTTCTGAAAATACAAGCCTTCCTGCAGAAGAAGCAAACGGGAGCCTTTCTGAA
  GAAGAAGCGAACGGGCCAGAGTTGGGGTCTGGAAAAGCCATGGAAGATACCTCTGGGGAA
  CCCGCTGCAGAGGACGAGGGAGACACCGCTTGGAACTACAGCTTCTCCCAGCTGCCTCGA
  TTTCTCAGTGGTTCCTGGTCAGAGTTCAGCACCCAACCTGAGAACTTCTTGAAAGGCTGT
  AAGTGGGCTCCTGACGGTTCCTGCATCTTGACCAATAGTGCTGATAACATCTTGCGAATT
  TATAACCTGCCCCCAGAGCTGTACCATGAGGGGGAGCAGGTGGAATATGCAGAAATGGTC
  CCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTATTCTCTGATG
  TCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCAT
  ATCTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGAT
  GAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTGGC
  TTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGA
  GCCACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCA
  GCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTATGCCTGGGAT
  GATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTT
  CATCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGG
  GATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACCACCAATCAG
  CGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGG
  GCTGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTG
  AGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGCCTGCCTCTC
  CTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGA
  GAGGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAG
  CTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAGGGCGAGAAA
  GGGCAGGGAGGAACGGAGGGAGGTGTGGGTGAGCTGATATAAAAAGGTTTTTATGATAAA
  AAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001143990
• ORF Size: 1647 bp
• Insert Size: 1800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001143990.1.

Reference Data

• RefSeq: NM_001143990.1, NP_001137462.1
• RefSeq Size: 1837
• RefSeq ORF: 1647
• Locus ID: 55135
• Gene Summary: This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]
  Transcript Variant: This variant (2, also known as WRAP53gamma) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein.