PTPH1 (PTPN3) (NM_001145369) Human Untagged Clone

CAT#: SC325329

PTPN3 (untagged)-Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPN3
• Synonyms: PTP-H1; PTPH1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001145369, the custom clone sequence may differ by one or more nucleotides
  ATGGATATTTGCGAAGGAAGGTTAACCTGCCCTCTTAACTCAGCAGTGGTTCTAGCGTCC
  TATGCCGTACAATCTCATTTTGGAGACTATAATTCTTCCATACATCATCCAGGCTATCTT
  TCCGATAGTCACTTTATACCCGATCAAAATGAGGACTTTTTAACAAAAGTCGAATCTCTG
  CATGAGCAGCACAGTGGGCTAAAACAATCAGAAGCAGAATCCTGCTATATCAACATAGCG
  CGGACCCTCGACTTCTATGGAGTAGAACTGCACAGTGGTAGGGATCTGCACAATTTAGAC
  CTAATGATTGGAATTGCTTCCGCGGGTGTTGCTGTGTACCGAAAATACATTTGCACAAGT
  TTCTATCCTTGGGTGAACATTCTCAAAATTTCTTTCAAAAGGAAAAAGTTCTTCATACAT
  CAGCGACAGAAACAGGCTGAATCCAGGGAACATATTGTGGCCTTCAACATGCTGAATTAC
  CGATCTTGCAAAAACTTGTGGAAATCCTGTGTTGAGCACCATACGTTCTTTCAGGCAAAG
  AAGCTACTACCTCAGGAAAAGAATGTTCTGTCTCAGTACTGGACTATGGGCTCTCGGAAC
  ACCAAAAAGTCGGTAAATAACCAATATTGCAAAAAGGTGATTGGCGGGATGGTGTGGAAC
  CCAGCCATGCGGAGATCCTTATCAGTGGAGCACTTAGAAACCAAGAGTCTGCCTTCTCGT
  TCCCCTCCCATTACTCCCAACTGGCGAAGTCCTCGGCTCCGGCACGAAATCCGAAAGCCA
  CGCCACTCTTCTGCAGATAACCTTGCAAATGAAATGACCTACATCACGGAAACGGAAGAT
  GTATTTTACACGTACAAGGGCTCTCTGGCCCCTCAAGACAGCGATTCTGAAGTTTCTCAG
  AACCGAAGCCCGCACCAAGAGAGTTTATCCGAGAACAATCCGGCACAAAGCTACCTGACC
  CAGAAGTCATCCAGTTCTGTGTCTCCATCTTCAAATGCTCCAGGCTCCTGCTCACCTGAC
  GGCGTTGATCAGCAGCTCTTAGATGACTTCCACAGGGTGACCAAAGGGGGCTCCACCGAG
  GACGCCAGCCAGTACTACTGTGACAAGAATGATAATGGTGACAGCTACTTAGTCTTGATC
  CGTATCACACCAGATGAAGATGGAAAATTTGGATTTAATCTTAAGGGAGGAGTGGATCAA
  AAGATGCCTCTTGTGGTATCAAGGATAAACCCAGAGTCACCTGCGGACACCTGCATTCCT
  AAGCTGAACGAAGGGGATCAAATCGTGTTAATCAATGGCCGGGACATCTCAGAACACACG
  CATGACCAAGTGGTGATGTTCATCAAAGCCAGCCGGGAGTCCCACTCACGGGAGCTGGCC
  CTGGTGATCAGGAGGAGAGCTGTCCGCTCATTTGCTGACTTCAAGTCTGAAGATGAACTG
  AACCAGCTTTTCCCCGAAGCCATTTTCCCCATGTGTCCGGAGGGTGGGGACACTTTGGAG
  GGATCCATGGCACAGCTAAAGAAGGGCCTCGAAAGCGGGACGGTGCTGATCCAGTTTGAG
  CAACTCTACAGAAAAAAGCCAGGTTTGGCCATCACGTTTGCAAAGCTGCCTCAAAATTTG
  GACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCACCCGGGTATTATTGCAGGGA
  AATGAAGATTATATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTG
  AACAAGTACATCGCCACTCAGGGGCCCCTGCCGCATACCTGTGCACAGTTTTGGCAGGTT
  GTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGACTCTCACAGAACGAGGGCGG
  ACCAAATGTCACCAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCAC
  ATCCAGTGTCAGTCAGAGGACTGCACCATCGCCTATGTGTCCCGAGAAATGCTGGTCACA
  AACACCCAGACCGGGGAAGAACACACAGTGACACATCTCCAGTACGTCGCATGGCCTGAC
  CACGGTGTGCCCGATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTG
  AGAGTGGACAGCGAGCCCGTCCTAGTTCACTGCAGTGCTGGAATAGGTCGAACCGGTGTG
  TTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGAACCTGCCCATTTACCCACTG
  GATATTGTCCGAAAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTAC
  AAGTTTGTGTGTGAAGCGATTCTTCGTGTGTATGAAGAAGGTTTAGTCCAAATGCTGGAT
  CCTAGT
  
• Restriction Sites: Please inquire
• ACCN: NM_001145369
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001145369.1, NP_001138841.1
• RefSeq Size: 8783 bp
• RefSeq ORF: 2349 bp
• Locus ID: 5774
• Cytogenetics: 9q31.3
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]'
  Transcript Variant: This variant (3) differs in the 5' UTR, and initiates translation from an in-frame downstream AUG, resulting in an isoform (3) with a shorter N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.