ANKRD25 (KANK2) (NM_001136191) Human Untagged Clone

CAT#: SC325361

KANK2 (untagged)-Human KN motif and ankyrin repeat domains 2 (KANK2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KANK2
• Synonyms: ANKRD25; MXRA3; NPHS16; PPKWH; SIP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC325361 sequence for NM_001136191 edited (data generated by NextGen Sequencing)
  
  
  ATGGCCCAGGTCCTGCACGTGCCTGCTCCCTTCCCAGGGACCCCTGGCCCAGCCTCCCCACCTGCCTTCC
  CTGCCAAGGACCCCGATCCACCCTACTCCGTGGAGACCCCCTATGGCTACCGCCTGGACCTGGACTTCCT
  CAAGTACGTGGATGACATCGAGAAGGGCCACACGCTGCGACGCGTGGCAGTGCAGCGCCGCCCCCGCCTG
  AGCTCGCTGCCCCGTGGCCCTGGCTCCTGGTGGACGTCCACTGAGTCGCTGTGCTCCAATGCCAGTGGGG
  ACAGCCGCCACTCAGCCTATTCCTACTGCGGCCGTGGCTTCTACCCTCAGTATGGTGCTCTGGAGACCCG
  CGGTGGCTTCAATCCGCGGGTGGAGCGCACGCTGCTGGATGCCCGTCGCCGTCTCGAGGACCAGGCGGCC
  ACACCCACCGGCCTGGGCTCCCTGACCCCCAGTGCGGCCGGCTCGACAGCCTCCCTGGTGGGCGTGGGGT
  TGCCACCCCCGACACCACGGAGTTCAGGACTGTCCACACCGGTGCCTCCCAGTGCCGGGCACCTGGCCCA
  CGTGCGGGAGCAGATGGCGGGTGCCCTGCGGAAGCTGCGGCAGCTGGAGGAGCAGGTGAAGCTGATCCCT
  GTGCTCCAGGTGAAGCTCTCGGTGCTCCAGGAGGAAAAGCGGCAGCTCACAGTACAACTTAAGAGCCAGA
  AGTTCCTGGGCCACCCCACAGCGGGCCGGGGTCGCAGCGAGCTCTGCCTGGACCTCCCCGATCCCCCAGA
  GGACCCAGTGGCACTGGAGACCCGGAGTGTGGGCACCTGGGTTCGAGAACGGGACTTGGGCATGCCTGAT
  GGGGAGGCTGCCCTCGCCGCCAAGGTCGCTGTGCTGGAGACCCAGCTCAAGAAGGCGCTGCAGGAGCTGC
  AGGCAGCTCAGGCCCGGCAGGCTGACCCCCAGCCCCAGGCCTGGCCACCGCCGGACAGCCCGGTCCGCGT
  GGATACAGTCCGGGTGGTAGAAGGGCCACGGGAGGTGGAGGTGGTGGCCAGCACAGCCGCTGGCGCCCCC
  GCACAGCGGGCCCAGAGCCTGGAGCCTTACGGCACAGGGCTGAGGGCCCTGGCAATGCCTGGTAGGCCTG
  AGAGCCCACCTGTGTTCCGCAGCCAGGAGGTGGTGGAGACAATGTGCCCAGTGCCCGCTGCAGCTACCAG
  CAACGTCCATATGGTGAAGAAGATTAGCATCACAGAGCGAAGCTGCGATGGAGCAGCAGGCCTCCCAGAA
  GTTCCTGCCGAATCGTCTTCGTCACCCCCGGGGTCCGAGGTAGCCTCCCTTACACAGCCTGAGAAGAGCA
  CAGGCCGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAGGCAAGCAGCCTCCCAAGAGTCCGA
  GGAGGCCGGGGGCACCGGCGGGCCCCCGGCAGGCGTGCGATCTATCATGAAACGGAAAGAGGAGGTTGCA
  GACCCCACGGCCCACCGGAGGAGCCTCCAGTTCGTGGGGGTCAACGGCGGGTATGAGTCGTCATCCGAGG
  ACTCCAGCACAGCAGAGAACATCTCAGACAACGACAGCACAGAGAACGAGGCCCCAGAGCCGAGGGAGAG
  GGTTCCGAGTGTGGCCGAAGCCCCCCAGCTCAGGCCTGCAGGGACGGCAGCGGCCAAGACCAGCCGGCAG
  GAGTGTCAGCTGTCTCGAGAATCTCAGCACATACCCACTGCTGAGGGGGCATCAGGATCAAACACGGAGG
  AGGAGATCAGGATGGAGCTAAGCCCTGACCTCATCTCAGCCTGCTTGGCCCTGGAAAAGTACCTGGACAA
  TCCCAACGCCCTCACAGAGCGGGAGCTGAAAGTGGCCTACACCACAGTGCTGCAGGAGTGGCTGCGCCTG
  GCCTGCCGCAGCGACGCACACCCCGAGCTGGTGCGGCGGCACCTGGTCACGTTCCGGGCCATGTCTGCGC
  GGCTGCTGGACTACGTGGTCAACATCGCCGACAGCAACGGCAACACAGCCCTGCACTACTCCGTGTCTCA
  TGCCAACTTCCCCGTGGTGCAGCAGCTGCTCGACAGCGGTGTCTGCAAGGTGGACAAACAGAACCGTGCT
  GGCTACAGCCCTATTATGCTCACCGCCCTGGCCACCCTGAAGACCCAGGACGACATCGAGACTGTCCTTC
  AGCTCTTCCGGCTTGGCAACATCAATGCCAAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTGGCCGT
  CAGCCACGGGCGGGTGGACGTTGTCAAAGCCCTGCTGGCCTGTGAGGCAGATGTCAACGTGCAAGATGAT
  GACGGCTCCACGGCCCTCATGTGCGCCTGTGAGCACGGCCACAAGGAGATCGCGGGGCTGCTGCTGGCCG
  TGCCCAGCTGTGACATCTCACTCACAGATCGCGATGGGAGCACAGCTCTGATGGTGGCCTTGGACGCAGG
  GCAGAGTGAGATTGCGTCCATGCTGTATTCCCGCATGAACATCAAGTGCTCGTTTGCCCCAATGTCAGAT
  GACGAGAGCCCTACATCATCCTCGGCAGAAGAGTAG
  
  Clone variation with respect to NM_001136191.2
  
• Restriction Sites: Please inquire
• ACCN: NM_001136191
• ORF Size: 2556 bp
• Insert Size: 3800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001136191.1, NP_001129663.1
• RefSeq Size: 5224
• RefSeq ORF: 2556
• Locus ID: 25959
• Gene Summary: This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016]
  Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site in the central coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Both variants 2 and 3 encode the same isoform (2).