CEMIP2 (NM_001135820) Human Untagged Clone

CAT#: SC325411

TMEM2 (untagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CEMIP2
• Synonyms: TMEM2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001135820, the custom clone sequence may differ by one or more nucleotides
  ATGTATGCCACTGATTCCAGGGGACACTCCCCTGCTTTCCTCCAACCTCAGAATGGAAAT
  AGTCGTCACCCATCTGGCTATGTTCCAGGGAAGGTTGTCCCATTGCGTCCCCCTCCTCCT
  CCAAAGAGTCAAGCTTCAGCCAAATTTACCTCCATCAGACGAGAAGACCGGGCAACCTTC
  GCATTCTCACCTGAAGAACAGCAAGCCCAGAGAGAAAGTCAAAAGCAAAAGAGACACAAA
  AATACTTTCATTTGTTTTGCTATTACTAGTTTCTCATTTTTTATTGCACTTGCAATCATT
  TTAGGAATATCCTCAAAATATGCTCCAGATGAAAATTGCCCAGATCAAAATCCTCGTCTC
  AGGAATTGGGATCCAGGACAAGATTCTGCAAAGCAAGTTGTTATCAAGGAGGGAGATATG
  CTCCGTCTGACCTCAGACGCCACCGTGCATTCTATAGTCATTCAGGATGGAGGACTGCTT
  GTATTTGGGGACAATAAAGATGGATCCAGAAATATTACTTTGAGGACTCATTACATCCTG
  ATCCAGGATGGTGGGGCGCTTCATATTGGAGCAGAAAAATGCCGCTATAAATCCAAAGCG
  ACAATTACCTTGTATGGCAAGTCAGATGAAGGTGAAAGTATGCCAACATTTGGCAAAAAG
  TTTATTGGTGTGGAAGCTGGCGGGACACTGGAGTTACATGGGGCACGGAAGGCATCGTGG
  ACGTTGTTGGCAAGGACCCTGAATTCCTCAGGCTTGCCCTTTGGGTCCTATACCTTTGAA
  AAGGACTTTTCCCGGGGCCTCAATGTGAGGGTCATTGACCAAGACACGGCCAAAATTTTG
  GAAAGTGAGAGATTTGATACCCATGAATACCGCAATGAGAGCAGGCGGCTTCAGGAGTTT
  CTGAGATTCCAGGATCCAGGTCGGATTGTTGCCATAGCTGTCGGGGATTCAGCCGCTAAA
  AGTCTCTTACAAGGAACCATCCAGATGATCCAGGAACGGTTGGGAAGTGAACTGATCCAA
  GGACTGGGCTACAGGCAAGCTTGGGCTTTAGTTGGTGTCATTGATGGTGGAAGCACTTCT
  TGCAATGAATCCGTGAGAAACTATGAAAATCATAGCAGTGGCGGGAAGGCTCTTGCCCAA
  AGAGAATTTTATACTGTGGATGGCCAGAAGTTCTCTGTGACAGCTTATAGTGAATGGATT
  GAAGAAACCCCTCAGTTCCTGCACATGGGTGAGATCATAGACGGTGTAGACATGAGAGCT
  GAGGTTGGAATTCTTACCCGGAATATTGTGATCCAAGGAGAAGTGGAGGACTCATGCTAC
  GCAGAAAATCAGTGCCAATTTTTTGATTATGATACCTTTGGGGGACACATTATGATAATG
  AAAAATTTTACTTCAGTCCATCTTTCTTATGTGGAATTGAAACACATGGGTCAGCAGCAG
  ATGGGGCGATACCCTGTTCATTTTCACCTGTGTGGTGACGTGGATTATAAAGGAGGATAC
  AGACATGCAACATTTGTGGACGGCCTGTCTATTCATCACAGCTTCTCAAGGTGCATCACT
  GTGCATGGGACAAATGGCTTGCTAATAAAAGACACCATTGGGTTTGACACACTAGGTCAT
  TGTTTCTTTTTGGAAGATGGTATTGAACAGAGGAATACTTTGTTCCACAATCTGGGACTC
  CTCACCAAGCCGGGTACTCTCCTGCCCACCGATAGGAACAACTCCATGTGTACCACCATG
  CGAGATAAAGTGTTTGGAAATTACATTCCTGTGCCTGCTACTGACTGTATGGCTGTTTCA
  ACTTTCTGGATTGCTCATCCCAACAATAATCTGATTAATAATGCAGCTGCAGGCTCACAG
  GATGCTGGAATATGGTATTTATTCCACAAGGAACCAACTGGGGAATCCAGTGGATTGCAG
  CTCTTGGCAAAACCAGAACTCACTCCATTGGGTATATTTTATAACAACAGGGTCCATTCA
  AATTTTAAGGCTGGCTTATTTATTGACAAAGGTGTCAAAACAACCAACTCTAGTGCTGCT
  GACCCAAGGGAATACCTCTGTTTGGACAATAGTGCAAGATTTCGACCTCATCAGGATGCA
  AACCCCGAAAAACCACGTGTTGCTGCTCTAATTGACAGGCTCATTGCTTTTAAAAATAAT
  GATAATGGAGCTTGGGTCAGAGGAGGAGATATTATCGTTCAAAATTCAGCATTTGCAGAT
  AATGGAATAGGACTGACCTTTGCCAGTGATGGAAGCTTCCCAAGTGATGAAGGTTCCAGC
  CAAGAGGTATCTGAATCTCTCTTTGTTGGGGAGAGCAGGAATTACGGCTTTCAGGGTGGT
  CAGAACAAGTATGTAGGCACTGGAGGAATAGACCAGAAGCCTCGAACATTACCCAGGAAC
  AGGACGTTCCCAATTAGAGGCTTTCAGATTTATGATGGGCCCATTCATCTCACAAGGAGC
  ACTTTCAAAAAATATGTGCCAACTCCAGATAGGTACAGCAGTGCAATTGGCTTCCTCATG
  AAGAATTCCTGGCAGATAACCCCCAGGAATAATATCTCCCTCGTGAAGTTTGGTCCACAT
  GTCTCTCTGAATGTCTTTTTTGGAAAGCCTGGTCCCTGGTTTGAAGATTGTGAGATGGAT
  GGTGATAAGAACTCCATATTCCATGACATTGATGGCTCTGTGACAGGATACAAGGATGCT
  TATGTGGGAAGAATGGACAACTACCTGATCCGCCATCCAAGCTGTGTAAATGTGTCTAAG
  TGGAATGCAGTGATCTGCAGTGGGACCTATGCACAGGTCTATGTACAGACATGGAGCACT
  CAGAATCTTTCTATGACCATTACACGAGATGAGTATCCGTCCAACCCTATGGTGCTCCGA
  GGTATTAATCAGAAGGCTGCCTTTCCACAGTACCAGCCTGTCGTCATGCTGGAGAAGGGT
  TATACCATCCACTGGAATGGGCCGGCACCACGGACTACATTTCTATACCTCGTCAACTTC
  AACAAGAATGACTGGATTCGAGTTGGCCTTTGCTATCCATCAAACACAAGTTTTCAAGTT
  ACCTTTGGCTATTTGCAGCGGCAGAATGGCTCATTATCCAAAATCGAAGAATATGAGCCT
  GTGCATTCACTGGAAGAACTGCAAAGAAAGCAATCCGAGAGGAAATTCTATTTTGACTCC
  AGCACGGGGTTACTGTTTTTGTATCTCAAAGCCAAAAGCCACAGGCATGGCCACAGTTAC
  TGTTCATCTCAGGGATGTGAAAGAGTCAAGATCCAAGCAGCCACAGACTCAAAGGACATC
  AGTAACTGCATGGCCAAAGCATACCCACAGTACTACAGAAAGCCGTCAGTGGTCAAGCGG
  ATGCCGGCCATGCTCACTGGACTCTGTCAAGGCTGTGGCACTCGGCAGGTGGTGTTTACT
  AGTGATCCTCATAAAAGTTACCTCCCTGTGCAATTCCAGTCACCTGATAAAGCAGAAACC
  CAGCGTGGAGACCCGTCTGTTATTTCTGTCAATGGCACTGACTTTACCTTCCGAAGTGCA
  GGCGTCCTCCTCCTTGTTGTGGATCCGTGCAGCGTTCCATTCCGCTTGACGGAAAAAACG
  GTTTTTCCTCTTGCTGATGTCAGTCGCATTGAAGAGTATTTAAAAACAGGCATCCCTCCA
  AGGTCCATTGTTCTGTTGAGCACAAGAGGAGAAATAAAGCAGTTAAACATTTCACACTTA
  CTAGTACCTCTGGGATTAGCCAAACCAGCTCATCTTTATGACAAAGGGAGTACCATATTT
  TTGGGATTCAGTGGAAACTTTAAACCATCATGGACTAAGCTATTTACCAGTCCTGCTGGA
  CAGGGCCTTGGGGTGCTTGAACAATTCATACCTTTGCAGCTGGACGAATATGGTTGTCCC
  AGAGCCACCACTGTCCGCAGAAGAGACCTGGAACTGCTAAAGCAAGCTTCAAAAGCACAT
  
• Restriction Sites: Please inquire
• ACCN: NM_001135820
• ORF Size: 3963 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001135820.1, NP_001129292.1
• RefSeq Size: 6351
• RefSeq ORF: 3963
• Locus ID: 23670
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (b) has the same N- and C-termini but is shorter compared to isoform a.