FLASH (CASP8AP2) (NM_001137668) Human Untagged Clone

CAT#: SC325424

CASP8AP2 (untagged)-Human caspase 8 associated protein 2 (CASP8AP2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CASP8AP2
• Synonyms: CED-4; FLASH; RIP25
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001137668, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGCAGATGATGACAATGGTGATGGAACAAGTTTATTTGATGTCTTTTCTGCTTCTCCTCTTAAGA
  ACAATGATGAAGGCTCACTGGACATATACGCTGGGTTGGACAGTGCTGTTTCTGACAGCGCTTCCAAATC
  CTGTGTACCATCAAGAAATTGTTTGGACTTATATGAAGAGATCCTGACTGAAGAAGGAACTGCAAAGGAG
  GCAACATATAATGATTTGCAAGTAGAATATGGAAAATGTCAACTACAAATGAAAGAGCTGATGAAAAAAT
  TTAAAGAAATACAGACACAGAATTTCAGCTTAATAAACGAAAACCAGTCTCTTAAGAAGAATATTTCAGC
  ACTTATCAAAACTGCCAGAGTGGAAATAAACCGCAAGGATGAAGAAATAAGTAATCTTCACCAAAGATTG
  TCTGAGTTTCCACATTTTCGAAATAATCATAAAACTGCAAGGACATTTGATACAGTTAAAACAAAAGATC
  TTAAATCTAGATCTCCACATTTGGATGATTGTTCAAAGACTGATCACAGAGCTAAAAGTGATGTTTCTAA
  AGATGTACATCATAGCACTTCACTGCCAAATCTGGAAAAGGAAGGAAAACCACATTCTGATAAAAGGAGT
  ACTTCACATTTACCTACATCTGTTGAGAAACACTGCACTAATGGTGTTTGGTCACGTTCTCATTATCAGG
  TTGGCGAGGGTAGCTCAAATGAGGATAGTAGAAGAGGAAGAAAAGATATTAGACATAGCCAGTTTAACAG
  AGGAACTGAAAGAGTACGAAAAGACTTAAGTACTGGCTGTGGTGATGGTGAACCAAGGATATTGGAGGCT
  AGTCAAAGGCTACAAGGACATCCTGAGAAATATGGTAAAGGTGAACCAAAGACTGAAAGCAAAAGTTCGA
  AGTTTAAAAGTAACTCAGATTCTGACTATAAAGGTGAACGCATTAACTCTTCTTGGGAGAAAGAGACCCC
  TGGAGAAAGGTCACACAGTCGAGTAGACTCTCAAAGTGACAAAAAACTAGAAAGACAAAGTGAAAGATCA
  CAAAATATAAATAGGAAAGAAGTTAAATCACAAGACAAAGAAGAAAGAAAAGTTGATCAAAAACCTAAAT
  CAGTAGTAAAGGACCAAGATCACTGGAGAAGATCTGAACGAGCATCACTTCCTCATTCCAAGAATGAAAT
  AACATTTTCTCATAATTCAAGTAAATACCATCTAGAAGAGAGAAGAGGATGGGAAGATTGTAAAAGAGAC
  AAGAGTGTAAACAGTCATAGTTTTCAAGATGGAAGATGTCCATCTTCTCTTTCAAACAGTAGAACTCACA
  AAAACATTGACTCTAAGGAAGTTGATGCCATGCATCAGTGGGAAAATACACCTTTAAAAGCAGAAAGACA
  TAGAACTGAAGATAAGAGGAAAAGAGAACAAGAAAGCAAAGAAGAAAATAGGCATATTAGAAATGAAAAA
  AGAGTACCTACAGAACATTTGCAGAAGACTAATAAGGAAACTAAGAAAACCACTACTGATTTAAAGAAAC
  AGAATGAACCAAAGACTGATAAGGGAGAAGTCCTTGATAATGGTGTTTCTGAAGGAGCAGATAATAAAGA
  GCTTGCAATGAAAGCTGAGAGTGGTCCAAATGAAACAAAAAACAAGGACCTAAAATTGAGTTTTATGAAA
  AAATTGAACTTAACTCTTTCTCCTGCTAAAAAGCAACCTGTTTCCCAGGATAATCAGCATAAAATAACTG
  ATATTCCCAAGTCCAGTGGTGTATGTGATTCAGAGTCTTCAATGCAAGTTAAAACAGTGGCATATGTTCC
  CTCCATAAGTGAACATATCTTGGGGGAAGCAGCTGTCAGTGAACATACCATGGGGGAAACCAAGTCAACG
  TTATTGGAACCAAAGGTTGCTCTTCTAGCAGTGACTGAACCCAGGATCGGTATCTCAGAAACCAACAAGG
  AAGACGAAAATAGTTTGTTAGTTAGGTCTGTTGACAATACTATGCATTGTGAAGAGCCCATTTGTGGTAC
  AGAGACTTCCTTCCCATCTCCTATGGAAATACAACAGACAGAATCCTTGTTTCCATCAACAGGAATGAAA
  CAAACCATTAATAATGGAAGGGCAGCAGCTCCTGTGGTAATGGATGTATTACAAACAGATGTGTCTCAAA
  ACTTTGGCTTGGAATTGGATACCAAAAGAAATGATAATTCAGATTATTGTGGTATTTCTGAAGGTATGGA
  GATGAAGGTGGCACTTTCAACAACAGTGAGTGAAACCACTGAAAGCATTTTGCAGCCTTCAATTGAGGAA
  GCTGATATTTTGCCAATAATGCTTTCAGAAGATAATAACCCAAAATTTGAGCCTTCTGTTATAGTTACAC
  CACTGGTTGAGAGTAAGTCGTGTCATCTGGAGCCTTGCTTACCTAAAGAGACTCTAGATTCTTCACTTCA
  GCAGACTGAGTTAATGGACCACAGAATGGCAACTGGTGAAACAAACTCAGTATATCATGATGATGATAAC
  TCGGTTTTGAGCATTGACCTTAATCACCTGAGACCTATTCCAGAAGCCATCAGTCCTCTGAATAGTCCAG
  TGAGACCTGTAGCAAAAGTTCTTAGAAATGAAAGCCCACCTCAAGTTCCAGTGTATAATAACAGTCATAA
  AGATGTGTTTTTACCAAATTCAGCTCATTCTACCTCTAAGAGTCAGTCTGATCTCAATAAGGAAAATCAA
  AAGCCAATTTACAAATCTGACAAATGTACAGAAGCAGACACATGTAAGAATTCACCATTAGATGAATTAG
  AAGAAGGAGAAATTAGAAGTGATAGTGAAACATCTAAACCACAAGAAAGTTTTGAAAAAAATTCCAAACG
  TAGAGTGTCAGCTGATGTGCGGAAGTCAAAGACTATCCCACGACGTGGGAAAAGTACTGTGTGTTTAGAT
  AAAGACAGTAGGAAAACACATGTAAGAATCCATCAGACCAATAACAAATGGAATAAAAGACCTGATAAAT
  CTAGCAGATCTTCAAAAACAGAGAAGAAAGATAAAGTGATGAGCACTTCCAGCTTGGAAAAAATAGTTCC
  AATTATTGCTGTACCCTCTTCTGAACAAGAGATCATGCACATGTTACGAATGATAAGAAAACATGTAAGA
  AAAAATTATATGAAATTCAAGGCAAAATTTTCATTAATACAATTTCACAGAATTATTGAGTCAGCAATTT
  TGAGTTTTACATCTTTAATTAAACATCTCAACTTACACAAAATCTCTAAGTCAGTGACTACCTTACAGAA
  GAATCTCTGTGATATTATAGAGTCTAAACTTAAGCAAGTTAAAAAGAATGGCATAGTTGATCGTTTATTT
  GAACAGCAACTACCAGATATGAAAAAAAAATTGTGGAAGTTTGTAGATGACCAACTTGATTATTTGTTTG
  CAAAGCTTAAGAAAATCTTAGTATGTGATTCCAAAAGCTTTGGAAGAGATAGTGATGAAGGCAAACTTGA
  AAAAACAAGTAAACAGAATGCACAGTATTCAAATAGTCAGAAAAGGAGTGTGGACAACTCCAACAGAGAA
  TTGCTGAAAGAAAAATTATCAAAATCAGAAGACCCTGTTCATTATAAGTCTTTAGTGGGATGTAAAAAAT
  CTGAGGAAAATTATCAAGACCAAAATAACTCCAGTATTAACACTGTAAAGCATGACATTAAAAAAAATTT
  TAACATCTGCTTTGATAATATAAAGAACTCTCAATCCGAAGAGCGCTCCTTGGAAGTACACTGTCCAAGC
  ACCCCAAAGTCAGAAAAAAACGAAGGAAGCAGCATAGAGGATGCACAGACATCCCAGCATGCAACTTTGA
  AGCCAGAACGAAGTTTCGAGATTCTTACCGAACAGCAAGCATCGAGCCTTACTTTTAATTTAGTGAGTGA
  TGCACAAATGGGTGAAATATTTAAAAGTTTGTTGCAAGGTTCTGATCTTTTAGACAGCAGTGTTAACTGT
  ACTGAAAAAAGTGAGTGGGAGTTAAAGACTCCAGAGAAGCAGCTGCTAGAGACTCTTAAGTGCGAGTCTA
  TACCAGCTTGTACAACAGAAGAGCTAGTTTCAGGGGTGGCTTCTCCATGTCCTAAAATGATTAGTGATGA
  TAATTGGTCATTATTATCATCTGAAAAAGGTCCATCTCTGTCTTCAGGGCTTTCATTGCCGGTTCATCCT
  GATGTGTTGGATGAAAGTTGTATGTTTGAAGTGTCTACTAACCTACCTTTAAGTAAAGATAATGTGTGTA
  GTGTAGAAAAGAGCAAGCCCTGCGTTTCTTCCATACTTCTTGAAGATCTAGCAGTCTCTTTAACAGTACC
  ATCGCCTCTGAAGTCAGATGGTCATCTCAGTTTTTTAAAGCCTGATATGTCGTCCAGTTCAACTCCTGAA
  GAAGTCATTAGTGCTCATTTTAGTGAAGATGCCTTACTTGAGGAAGAGGATGCATCTGAGCAAGATATTC
  ATTTAGCTCTGGAGTCTGATAATTCAAGCAGTAAATCAAGTTGTTCTTCTTCCTGGACAAGCCGATCTGT
  TGCTCCAGGCTTTCAGTACCACCCTAATCTACCTATGCATGCCGTCATAATGGAAAAGTCCAATGATCAT
  TTCATTGTGAAAATACGACGTGCAACACCATCTACCTCTTCTGGCCTTAAACAGAGTATGATGCCTGATG
  AATTATTGACATCTTTGCCCAGACATGGAAAGGAAGCTGATGAAGGACCAGAGAAAGAATATATTTCATG
  TCAGAACACAGTTTTTAAATCTGTGGAGGAATTGGAAAACTCCAACAAAAATGTTGATGGCAGCAAGTCA
  ACTCATGAAGAACAGAGCTCTATGATACAAACACAGGTTCCTGATATATATGAATTTCTTAAAGATGCTT
  CAGATAAGATGGGTCATAGTGATGAAGTGGCTGATGAATGTTTCAAATTGCATCAAGTATGGGAAACAAA
  AGTGCCTGAAAGCATTGAAGAATTGCCTTCAATGGAAGAAATCTCACACTCTGTTGGGGAACATCTTCCA
  AACACATACGTAGATCTAACGAAAGATCCAGTCACTGAAACCAAAAACTTGGGGGAATTCATAGAAGTAA
  CAGTTTTACATATTGATCAGTTGGGATGTTCTGGAGGCAATTTAAATCAGAGTGCTCAAATATTAGACAA
  TTCTTTGCAGGCTGATACTGTAGGTGCTTTTATTGATTTGACACAAGATGCTTCAAGTGAGGCTAAAAGT
  GAAGGTAATCATCCTGCATTAGCTGTGGAAGACTTGGGATGTGGGGTGATACAGGTAGATGAAGATAATT
  GTAAGGAAGAAAAGGCACAAGTGGCAAACAGGCCTTTAAAATGCATTGTTGAGGAAACCTATATCGACTT
  GACCACAGAATCTCCCAGTTCATGTGAAGTAAAAAAAGATGAGTTAAAATCAGAGCCAGGATCAAATTGT
  GATAACTCGGAGTTGCCTGGGACTTTGCATAATTCTCACAAAAAGAGAAGAAACATTTCTGATCTAAATC
  ATCCTCATAAAAAACAAAGAAAGGAAACAGACTTAACTAATAAGGAAAAGACCAAGAAACCTACCCAAGA
  TTCTTGTGAGAATACTGAAGCTCACCAAAAGAAAGCCAGTAAGAAGAAGGCCCCTCCTGTGACTAAAGAT
  CCCTCATCATTAAAGGCAACCCCAGGGATTAAGGATTCATCAGCAGCACTTGCCACTTCTACAAGTCTTT
  CTGCAAAAAATGTTATTAAAAAGAAGGGAGAAATTATCATTTTATGGACAAGAAATGATGACCGGGAAAT
  TTTATTGGAGTGTCAGAAAAGAGGGCCATCATTTAAAACATTTGCATATTTAGCCGCCAAGTTGGATAAA
  AATCCAAATCAGGTCTCAGAAAGATTCCAGCAGCTAATGAAGCTCTTTGAAAAGTCAAAATGCAGATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001137668
• ORF Size: 5949 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001137668.1, NP_001131140.1
• RefSeq Size: 6649
• RefSeq ORF: 5949
• Locus ID: 9994
• Protein Families: Druggable Genome
• Gene Summary: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1.