USP46 (NM_001134223) Human Untagged Clone

CAT#: SC325818

USP46 (untagged)-Human ubiquitin specific peptidase 46 (USP46), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: USP46
• Synonyms: FLJ11850; FLJ12552; FLJ14283; FLJ39393
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001134223, the custom clone sequence may differ by one or more nucleotides
  ATGAATTGTTTTCAGGGCACCAATGCCTCTGCTCTGGAAAAAGACATTGGTCCAGAGCAG
  TTTCCAATCAATGAACACTATTTCGGATTGGTCAATTTTGGAAACACATGCTACTGTAAC
  TCCGTGCTTCAGGCATTGTACTTCTGCCGTCCATTCCGGGAGAATGTGTTGGCATACAAG
  GCCCAGCAAAAGAAGAAGGAAAACTTGCTGACGTGCCTGGCGGACCTTTTCCACAGCATT
  GCCACACAGAAGAAGAAGGTTGGCGTCATCCCACCAAAGAAGTTCATTTCAAGGCTGAGA
  AAAGAGAATGATCTCTTTGATAACTACATGCAGCAGGATGCTCATGAATTTTTAAATTAT
  TTGCTAAACACTATTGCGGACATCCTTCAGGAGGAGAAGAAACAGGAAAAACAAAATGGA
  AAATTAAAAAATGGCAACATGAACGAACCTGCGGAAAATAATAAACCAGAACTCACCTGG
  GTCCATGAGATTTTTCAGGGAACGCTTACCAATGAAACTCGATGCTTGAACTGTGAAACT
  GTTAGTAGCAAAGATGAAGATTTTCTTGACCTTTCTGTTGATGTGGAGCAGAATACATCC
  ATTACCCACTGTCTAAGAGACTTCAGCAACACAGAAACACTGTGTAGTGAACAAAAATAT
  TATTGTGAAACATGCTGCAGCAAACAAGAAGCCCAGAAAAGGATGAGGGTAAAAAAGCTG
  CCCATGATCTTGGCCCTGCACCTAAAGCGGTTCAAGTACATGGAGCAGCTGCACAGATAC
  ACCAAGCTGTCTTACCGTGTGGTCTTCCCTCTGGAACTCCGGCTCTTCAACACCTCCAGT
  GATGCAGTGAACCTGGACCGCATGTATGACTTGGTTGCGGTGGTCGTTCACTGTGGCAGT
  GGTCCTAATCGTGGGCATTATATCACTATTGTGAAAAGTCACGGCTTCTGGCTTTTGTTT
  GATGATGACATTGTAGAGAAAATAGATGCTCAAGCTATTGAAGAATTCTATGGCCTGACG
  TCAGATATATCAAAAAATTCAGAATCTGGATATATTTTATTCTATCAGTCAAGAGAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001134223
• ORF Size: 1080 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001134223.1, NP_001127695.1
• RefSeq Size: 8057
• RefSeq ORF: 1080
• Locus ID: 64854
• Protein Families: Druggable Genome, Protease
• Gene Summary: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]). [supplied by OMIM, Jun 2009]
  Transcript Variant: This variant (2) contains an alternate 5'-terminal exon and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.