Leupaxin (LPXN) (NM_001143995) Human Untagged Clone

CAT#: SC325866

LPXN (untagged)-Human leupaxin (LPXN), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LPXN
• Synonyms: LDPL
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001143995, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCTACATTATTGATCTCGTCTTCCGATGCCTTATTGGAGGAACTGGAACGCTCCACCCTTCAGGACA
  GTGATGAATATTCCAACCCAGCTCCTCTTCCCCTGGATCAGCATTCCAGAAAGGAGACTAACCTTGATGA
  GACTTCGGAGATCCTTTCTATTCAGGATAACACAAGTCCCTTGCCGGCGCAGCTCGTGTATACTACCAAT
  ATCCAGGAGCTCAATGTCTACAGTGAAGCCCAAGAGCCAAAGGAATCACCACCACCTTCTAAAACGTCAG
  CAGCTGCTCAGTTGGATGAGCTCATGGCTCACCTGACTGAGATGCAGGCCAAGGTTGCAGTGAGAGCAGA
  TGCTGGCAAGAAGCACTTACCAGACAAGCAGGATCACAAGGCCTCCCTGGACTCAATGCTTGGGGGTCTG
  GAGCAGGAATTGCAGGACCTTGGCATTGCCACAGTGCCCAAGGGCCATTGTGCATCCTGCCAGAAACCGA
  TTGCTGGGAAGGTGATCCATGCTCTAGGGCAATCATGGCATCCTGAGCATTTTGTCTGTACTCATTGCAA
  AGAAGAGATTGGCTCCAGTCCCTTCTTTGAGCGGAGTGGCTTGGCCTACTGCCCCAACGACTACCACCAA
  CTTTTTTCTCCACGCTGTGCTTACTGCGCTGCTCCCATCCTGGATAAAGTGCTGACAGCAATGAACCAGA
  CCTGGCACCCAGAGCACTTCTTCTGCTCTCACTGCGGAGAGGTGTTTGGTGCAGAAGGCTTTCATGAGAA
  GGACAAGAAGCCATATTGCCGAAAGGATTTCTTAGCCATGTTCTCACCCAAGTGTGGTGGCTGCAATCGC
  CCAGTGTTGGAAAACTACCTTTCAGCCATGGACACTGTCTGGCACCCAGAGTGCTTTGTTTGTGGGGACT
  GCTTCACCAGTTTTTCTACTGGCTCCTTCTTTGAACTGGATGGACGTCCATTCTGTGAGCTCCATTACCA
  TCACCGCCGGGGAACGCTCTGCCATGGGTGTGGGCAGCCCATCACTGGCCGTTGTATCAGTGCCATGGGG
  TACAAGTTCCATCCTGAGCACTTTGTGTGTGCTTTCTGCCTGACACAGTTGTCGAAGGGCATTTTCAGGG
  AGCAGAATGACAAGACCTATTGTCAACCTTGCTTCAATAAGCTCTTCCCACTGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001143995
• ORF Size: 1176 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001143995.2, NP_001137467.1
• RefSeq Size: 1965
• RefSeq ORF: 1176
• Locus ID: 9404
• Protein Families: Druggable Genome
• Gene Summary: The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (1) encodes the longest isoform (1).