SIRPB1 (NM_001135844) Human Untagged Clone

CAT#: SC325880

SIRPB1 (untagged)-Human signal-regulatory protein beta 1 (SIRPB1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SIRPB1
• Synonyms: CD172b; SIRP-BETA-1
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001135844 edited
  ATGCCCGTGCCAGCCTCCTGGCCCCACCTTCCTAGTCCTTTCCTGCTGATGACGCTACTG
  CTGGGGAGACTCACAGGGGTAGCTGGCGAGGAAGAGCTGCAGGTGATTCAGCCTGACAAG
  TCCATATCAGTTGCAGCTGGAGAGTCGGCCACTCTGCACTGCACTGTGACTTCCCTGATC
  CCTGTGGGGCCCATCCAGTGGTTCAGAGGAGCTGGACCAGGCCGGGAATTAATCTACAAT
  CAGAAAGAAGGCCACTTCCCACGGGTAACAACTGTTTCAGACCTCACAAAGAGAAACAAC
  ATGGACTTTTCCATCCGCATCAGTAACATCACCCCAGCAGATGCCGGCACCTACTACTGT
  GTGAAGTTCCGGAAAGGGAGCCCCGACCACGTGGAGTTTAAGTCTGGAGCAGGCACCGAG
  CTGTCTGTGCGTGCCAAACCCTCTGCCCCCGTGGTATCGGGCCCTGCGGCGAGGGCCACA
  CCTCAGCACACAGTGAGCTTCACCTGCGAGTCCCACGGCTTCTCACCCAGAGACATCACC
  CTGAAATGGTTCAAAAATGGGAATGAGCTCTCAGACTTCCAGACCAACGTGGACCCCGCA
  GGAGACAGTGTGTCCTACAGCATCCACAGCACAGCCAAGGTGGTGCTGACCCGCGAGGAC
  GTTCACTCTCAAGTCATCTGCGAGGTGGCCCACGTCACCTTGCAGGGGGACCCTCTTCGT
  GGGACTGCCAACTTGTCTGAGACCATCCGAGTTCCACCCACCTTGGAGGTTACTCAACAG
  CCCGTGAGGGCAGAGAACCAGGTGAATGTCACCTGCCAGGTGAGGAAGTTCTACCCCCAG
  AGACTACAGCTGACCTGGTTGGAGAATGGAAACGTGTCCAGGACAGAAACGGCCTCAACC
  CTTACAGAAAACAAGGATGGTACCTACAACTGGATGAGCTGGCTCCTGGTGAATGTATCT
  GCCCACAGGGATGATGTGAAGCTCACCTGCCAGGTGGAGCATGACGGGCAGCCAGCGGTC
  AGCAAAAGCCATGACCTGAAGGTCTCAGCCCACCCGAAGGAGCAGGGCTCAAATACTGCT
  CCTGGCCCAGCACTGGCTTCTGCTGCTCCACTTCTCATAGCTTTCCTCCTGGGCCCCAAG
  GTGCTGCTGGTGGTTGGTGTCTCTGTCATCTATGTCTACTGGAAGCAGAAGGCCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001135844
• ORF Size: 1197 bp
• Insert Size: 1200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001135844.1, NP_001129316.1
• RefSeq Size: 2241
• RefSeq ORF: 1197
• Locus ID: 10326
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
  Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The encoded isoform (3) is the same length as isoform 1, but these isoforms differ in their amino acid sequences. Both variants 3 and 4 encode the same isoform (3).