HNRPLL (HNRNPLL) (NM_001142650) Human Untagged Clone

CAT#: SC326043

HNRPLL (untagged)-Human heterogeneous nuclear ribonucleoprotein L-like (HNRPLL), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HNRNPLL
• Synonyms: HNRPLL; SRRF
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001142650, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTGGCTCGGGAGACGTACGAGGAGGACCGGGAGTACGAGAGCCAGGCCAAGCGTCTCAAGACCGAGG
  AGGGGGAGATCGACTACTCGGCCGAGGAAGGCGAGAACCGCCGGGAAGCGACGCCCCGGGGCGGGGGCGA
  TGGCGGCGGCGGCGGCCGGAGCTTCTCTCAGCCGGAGGCAGGTGGAAGTCATCATAAAGTTTCTGTTTCA
  CCCGTCGTCCATGTTCGAGGACTCTGTGAATCTGTGGTGGAAGCAGACCTCGTGGAAGCGCTGGAAAAAT
  TTGGGACAATATGCTATGTGATGATGATGCCATTTAAACGACAGGCTCTAGTGGAATTTGAAAACATAGA
  TAGTGCCAAAGAATGTGTGACATTTGCTGCAGATGAACCCGTGTACATTGCTGGTCAACAGGCTTTTTTC
  AACTATTCTACAAGCAAAAGGATCACTCGGCCAGGAAATACTGATGATCCATCAGGAGGCAACAAAGTTC
  TTCTGCTCTCAATTCAGAATCCGCTTTATCCAATTACAGTGGATGTTTTATATACTGTATGCAACCCTGT
  TGGCAAAGTGCAACGTATTGTTATATTCAAGAGAAATGGGATACAAGCAATGGTTGAGTTTGAATCAGTC
  CTTTGTGCCCAGAAAGCTAAAGCAGCACTCAATGGAGCTGATATATATGCTGGATGTTGCACACTAAAAA
  TTGAATATGCACGGCCAACTCGTCTAAATGTTATTAGGAATGACAATGACAGTTGGGACTACACTAAACC
  ATATTTGGGAAGACGAGATAGAGGAAAGGGTCGCCAGAGACAAGCCATTTTGGGAGAACACCCTTCTTCG
  TTTAGACATGATGGCTATGGATCCCATGGTCCATTATTGCCTTTACCAAGTCGTTACAGAATGGGCTCTC
  GAGATACACCTGAACTTGTTGCTTATCCATTACCACAGGCTTCTTCCTCTTACATGCATGGAGGAAATCC
  CTCTGGTTCAGTTGTAATGGTTAGTGGATTACATCAACTAAAAATGAATTGTTCAAGAGTCTTCAACCTG
  TTCTGCTTATATGGAAATATTGAGAAGGTAAAATTTATGAAGACCATTCCTGGTACAGCACTGGTAGAAA
  TGGGTGATGAGTATGCTGTAGAAAGAGCTGTCACACACCTTAATAATGTCAAATTATTTGGGAAAAGACT
  TAATGTTTGCGTGTCTAAACAACATTCAGTTGTTCCAAGTCAAATATTTGAGCTGGAGGATGGTACCAGC
  AGCTACAAAGATTTTGCAATGAGCAAAAATAATCGCTTTACAAGTGCTGGCCAAGCATCTAAGAATATAA
  TCCAGCCACCCTCCTGTGTTTTGCATTATTATAATGTTCCATTGTGTGTCACAGAAGAGACCTTCACAAA
  GTTGTGTAATGACCATGAAGTTCTTACATTCATCAAATATAAAGTGTTTGATGCAAAACCTTCAGCCAAA
  ACACTTTCTGGGCTATTAGAATGGGAGTGCAAAACTGATGCAGTAGAAGCCCTTACGGCACTGAATCACT
  ATCAGATAAGAGTGCCGAATGGTTCCAATCCCTATACATTGAAGCTTTGCTTTTCTACATCATCCCATTT
  ATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001142650
• ORF Size: 1614 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001142650.1, NP_001136122.1
• RefSeq Size: 2797
• RefSeq ORF: 1614
• Locus ID: 92906
• Gene Summary: HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]). [supplied by OMIM, Aug 2008]
  Transcript Variant: Compared to variant 1, this variant (2) lacks a segment of the 5' UTR which results in the use of an alternative translation initiation site. These differences result in a protein (isoform 2) with a shorter and distinct N-terminus, compared to isoform 1.