SLC6A8 (NM_001142805) Human Untagged Clone

CAT#: SC326120

SLC6A8 (untagged)-Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC6A8
• Synonyms: CCDS1; CRT; CRTR; CT1; CTR5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001142805, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGAAGAAGAGCGCCGAGAACGGCATCTATAGCGTGTCCGGCGACGAGAAGAAGGGCCCCCTCATCG
  CGCCCGGGCCCGACGGGGCCCCGGCCAAGGGCGACGGCCCCGTGGGCCTGGGGACACCCGGCGGCCGCCT
  GGCCGTGCCGCCGCGCGAGACCTGGACGCGCCAGATGGACTTCATCATGTCGTGCGTGGGCTTCGCCGTG
  GGCTTGGGCAACGTGTGGCGCTTCCCCTACCTGTGCTACAAGAACGGCGGAGGTGTGTTCCTTATTCCCT
  ACGTCCTGATCGCCCTGGTTGGAGGAATCCCCATTTTCTTCTTAGAGATCTCGCTGGGCCAGTTCATGAA
  GGCCGGCAGCATCAATGTCTGGAACATCTGTCCCCTGTTCAAAGGCCTGGGCTACGCCTCCATGGTGATC
  GTCTTCTACTGCAACACCTACTACATCATGGTGCTGGCCTGGGGCTTCTATTACCTGGTCAAGTCCTTTA
  CCACCACGCTGCCCTGGGCCACATGTGGCCACACCTGGAACACTCCCGACTGCGTGGAGATCTTCCGCCA
  TGAAGACTGTGCCAATGCCAGCCTGGCCAACCTCACCTGTGACCAGCTTGCTGACCGCCGGTCCCCTGTC
  ATCGAGTTCTGGGAGAACAAAGTCTTGAGGCTGTCTGGGGGACTGGAGGTGCCAGGGGCCCTCAACTGGG
  AGGTGACCCTTTGTCTGCTGGCCTGCTGGGTGCTGGTCTACTTCTGTGTCTGGAAGGGGGTCAAATCCAC
  GGGAAAGATCGTGTACTTCACTGCTACATTCCCCTACGTGGTCCTGGTCGTGCTGCTGGTGCGTGGAGTG
  CTGCTGCCTGGCGCCCTGGATGGCATCATTTACTATCTCAAGCCTGACTGGTCAAAGCTGGGGTCCCCTC
  AGGTGTGGATAGATGCGGGGACCCAGATTTTCTTTTCTTACGCCATTGGCCTGGGGGCCCTCACAGCCCT
  GGGCAGCTACAACCGCTTCAACAACAACTGCTACAATGGGACCAGCTTCTTTGCTGGCTTCGTGGTCTTC
  TCCATCCTGGGCTTCATGGCTGCAGAGCAGGGCGTGCACATCTCCAAGGTGGCAGAGTCAGGGCCGGGCC
  TGGCCTTCATCGCCTACCCGCGGGCTGTCACGCTGATGCCAGTGGCCCCACTCTGGGCTGCCCTGTTCTT
  CTTCATGCTGTTGCTGCTTGGTCTCGACAGCCAGTTTGTAGGTGTGGAGGGCTTCATCACCGGCCTCCTC
  GACCTCCTCCCGGCCTCCTACTACTTCCGTTTCCAAAGGGAGATCTCTGTGGCCCTCTGTTGTGCCCTCT
  GCTTTGTCATCGATCTCTCCATGGTGACTGATGGCGGGATGTACGTCTTCCAGCTGTTTGACTACTACTC
  GGCCAGCGGCACCACCCTGCTCTGGCAGGCCTTTTGGGAGTGCGTGGTGGTGGCCTGGGTGTACGGAGCT
  GACCGCTTCATGGACGACATTGCCTGTATGATCGGGTACCGACCTTGCCCCTGGATGAAATGGTGCTGGT
  CCTTCTTCACCCCGCTGGTCTGCATGGGCATCTTCATCTTCAACGTTGTGTACTACGAGCCGCTGGTCTA
  CAACAACACCTACGTGTACCCGTGGTGGGGTGAGGCCATGGGCTGGGCCTTCGCCCTGTCCTCCATGCTG
  TGCGTGCCGCTGCACCTCCTGGGCTGCCTCCTCAGGGCCAAGGGCACCATGGCTGAGCGCTGGCAGCACC
  TGACCCAGCCCATCTGGGGCCTCCACCACTTGGAGTACCGAGCTCAGGACGCAGATGTCAGGGGCCTGAC
  CACCCTGACCCCAGTGTCCGAGAGCAGCAAGGTCGTCGTGGTGGAGAGTGTCATGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001142805
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001142805.1, NP_001136277.1
• RefSeq Size: 3550 bp
• RefSeq ORF: 1878 bp
• Locus ID: 6535
• Cytogenetics: Xq28
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: 'The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]'
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (2) lacks a 10-aa segment but has the same N- and C-termini, compared to isoform 1.