TRPC4 (NM_001135956) Human Untagged Clone

CAT#: SC326246

TRPC4 (untagged)-Human transient receptor potential cation channel, subfamily C, member 4 (TRPC4), transcript variant gamma

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRPC4
• Synonyms: HTRP-4; HTRP4; TRP4
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001135956, the custom clone sequence may differ by one or more nucleotides
  ATGGCTCAGTTCTATTACAAAAGAAATGTTAATGCTCCCTATAGAGACCGCATCCCTCTA
  AGGATAGTAAGAGCAGAATCAGAACTCTCGCCATCAGAAAAAGCCTACTTGAATGCTGTG
  GAAAAGGGAGATTATGCCAGTGTCAAGAAATCCCTAGAGGAAGCTGAAATTTATTTTAAA
  ATCAATATTAATTGCATTGATCCTCTCGGAAGAACTGCTCTCCTCATTGCAATTGAAAAT
  GAGAACTTGGAGCTCATCGAACTACTCTTAAGCTTTAATGTCTATGTTGGAGATGCTCTA
  TTACATGCTATCAGAAAAGAAGTCGTCGGAGCTGTTGAGCTGTTATTGAACCACAAAAAA
  CCTAGTGGAGAAAAACAGGTGCCTCCTATACTCCTTGATAAGCAGTTCTCTGAATTCACT
  CCAGACATTACACCAATCATTTTGGCAGCCCATACAAATAATTATGAGATAATAAAACTC
  TTGGTTCAGAAAGGAGTCTCAGTGCCTCGACCCCACGAGGTCCGCTGTAACTGTGTGGAA
  TGCGTGTCCAGTTCAGATGTGGACAGCCTCCGTCACTCACGCTCCAGACTCAACATCTAC
  AAGGCCTTGGCCAGTCCCTCTCTCATTGCACTGTCAAGCGAAGATCCTTTTCTCACAGCC
  TTTCAGTTAAGTTGGGAACTTCAGGAACTGAGCAAGGTGGAAAATGAATTCAAGTCGGAG
  TATGAAGAGCTGTCACGGCAGTGCAAACAATTTGCTAAGGACCTACTGGATCAGACGAGA
  AGTTCCAGAGAACTGGAAATCATTCTTAATTACCGAGATGACAATAGTCTCATAGAAGAA
  CAAAGTGGAAATGATCTTGCAAGACTAAAATTGGCCATTAAGTACCGTCAAAAAGAGTTT
  GTTGCCCAGCCCAATTGTCAACAGCTGCTGGCATCTCGCTGGTACGATGAGTTTCCAGGC
  TGGAGGAGAAGACACTGGGCAGTGAAGATGGTGACATGTTTCATAATAGGACTTCTTTTT
  CCTGTCTTCTCTGTGTGCTACCTGATAGCTCCCAAAAGCCCACTTGGACTGTTCATCAGG
  AAGCCATTTATCAAGTTTATCTGCCACACAGCCTCCTATTTGACTTTTTTGTTCCTGCTG
  CTGCTTGCCTCTCAGCACATCGACAGGTCAGACTTGAACAGGCAAGGTCCACCACCAACC
  ATCGTCGAGTGGATGATATTACCGTGGGTCCTGGGCTTCATATGGGGAGAAATTAAACAG
  ATGTGGGATGGCGGACTTCAGGACTACATCCATGATTGGTGGAATCTAATGGACTTTGTA
  ATGAACTCCTTATATTTAGCAACAATCTCCTTGAAAATTGTTGCATTTGTAAAGTACAGT
  GCCCTTAATCCACGAGAATCATGGGACATGTGGCATCCCACTCTGGTGGCAGAGGCTTTA
  TTTGCTATTGCAAACATCTTCAGTTCTCTGCGTCTGATCTCACTGTTTACTGCAAATTCT
  CACCTGGGACCTCTGCAAATATCTCTGGGAAGAATGCTCCTGGACATTTTGAAGTTTCTA
  TTCATATACTGCCTTGTGTTGCTAGCATTTGCAAATGGCCTAAATCAATTGTACTTCTAT
  TATGAAGAAACGAAAGGGTTAACCTGCAAAGGCATAAGATGTGAAAAGCAGAATAATGCA
  TTTTCAACGTTATTTGAGACACTGCAGTCCCTGTTTTGGTCAATATTTGGGCTCATCAAT
  TTATATGTGACCAATGTCAAAGCACAGCATGAATTTACTGAGTTTGTTGGTGCCACCATG
  TTTGGGACATACAATGTCATCTCTCTGGTTGTTCTACTCAACATGTTAATAGCTATGATG
  AATAATTCTTACCAACTGATTGCTAGGCGAGCTGCTGATAACTTGAGAAGACATCACCAA
  TACCAAGAAGTTATGAGGAACCTGGTGAAGCGATACGTTGCTGCAATGATTAGAGATGCT
  AAAACTGAAGAAGGCCTGACCGAAGAGAACTTTAAGGAACTAAAGCAAGACATTTCTAGT
  TTCCGCTTTGAAGTCCTGGGATTACTAAGAGGAAGCAAACTTTCCACAATACAATCTGCG
  AATGCCTCGAAGGAGTCTTCAAATTCGGCAGACTCAGATGAAAAGAGTGATAGCGAAGAA
  GAAGTTGCTCGTCAACAGGCTGCAGGACCACTTGAGAGAAATATTCAACTGGAATCTCGA
  GGATTAGCTTCACGGGGTGACCTGAGCATTCCCGGTCTCAGTGAACAATGTGTGTTAGTA
  GACCATAGAGAAAGGAATACGGACACACTGGGGTTACAGGTAGGAAAGAGAGTGTGTCCA
  TTCAAGTCAGAGAAGGTGGTGGTGGAGGACACGGTTCCTATAATACCAAAGGAGAAACAT
  GCAAAAGAAGAGGACTCTAGTATAGACTATGATCTAAACCTCCCAGACACAGTCACCCAC
  GAAGATTACGTGACCACAAGATTG
  
• Restriction Sites: Please inquire
• ACCN: NM_001135956
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001135956.1, NP_001129428.1
• RefSeq Size: 3087 bp
• RefSeq ORF: 2487 bp
• Locus ID: 7223
• Cytogenetics: 13q13.3
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Gene Summary: 'This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]'
  Transcript Variant: This variant (3, also known as gamma) lacks two in-frame segments, compared to variant 1 (alpha). This encoded isoform (gamma) is shorter, compared to isoform alpha. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.