VAV2 (NM_001134398) Human Untagged Clone

CAT#: SC326266

VAV2 (untagged)-Human vav 2 guanine nucleotide exchange factor (VAV2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VAV2
• Synonyms: VAV-2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001134398, the custom clone sequence may differ by one or more nucleotides
  ATGGAGCAGTGGCGGCAGTGCGGCCGCTGGCTCATCGATTGCAAGGTCCTGCCGCCCAAC
  CACCGGGTGGTGTGGCCCTCGGCCGTGGTCTTCGACCTGGCGCAGGCGCTGCGCGACGGG
  GTCCTTCTGTGCCAGCTGCTGCACAACCTCTCCCCCGGCTCCATCGACCTCAAGGACATC
  AACTTCCGGCCGCAGATGTCCCAGTTTCTGTGTTTGAAGAACATACGCACCTTCCTGAAA
  GTCTGCCACGATAAATTTGGATTAAGGAACAGCGAGCTGTTTGACCCCTTTGACCTCTTC
  GATGTGCGAGACTTTGGAAAGGTCATCTCCGCGGTGTCGAGGCTCTCCCTGCACAGCATC
  GCGCAGAACAAAGGGATCAGGCCTTTTCCCTCAGAGGAGACCACAGAGAATGACGATGAC
  GTCTACCGCAGCCTGGAGGAGCTGGCCGACGAGCATGACCTGGGGGAGGACATCTACGAC
  TGCGTCCCGTGTGAGGATGGAGGGGACGACATCTACGAGGACATCATCAAGGTGGAGGTG
  CAGCAGCCCATGATTAGATACATGCAGAAAATGGGCATGACTGAAGATGACAAGAGGAAC
  TGCTGCCTGCTGGAGATCCAGGAGACCGAGGCCAAGTACTACCGCACCCTGGAGGACATT
  GAGAAGAACTACATGAGCCCCCTGCGGCTGGTGCTGAGCCCGGCGGACATGGCAGCTGTC
  TTCATTAACCTGGAGGACCTGATCAAGGTGCATCACAGCTTCCTGAGGGCCATCGACGTG
  TCCGTGATGGTGGGGGGCAGCACGCTGGCCAAGGTCTTCCTCGATTTCAAGGAAAGGCTT
  CTGATCTACGGGGAGTACTGCAGCCACATGGAGCACGCCCAGAACACACTGAACCAGCTC
  CTGGCCAGCCGGGAGGACTTCAGGCAGAAAGTCGAGGAGTGCACACTGAAGGTCCAGGAT
  GGAAAATTTAAGCTGCAAGACCTGCTGGTGGTCCCCATGCAGAGGGTGCTCAAATACCAC
  CTGCTCTTGAAGGAGCTTCTGAGCCATTCTGCGGAACGGCCTGAGAGGCAGCAGCTCAAA
  GAAGCACTGGAAGCCATGCAGGACTTGGCGATGTACATCAATGAAGTTAAACGGGACAAG
  GAGACCTTGAGGAAAATCAGCGAATTTCAGAGTTCTATAGAAAATTTGCAAGTGAAACTG
  GAGGAATTTGGAAGACCAAAGATTGACGGGGAACTGAAAGTCCGGTCCATAGTCAACCAC
  ACCAAGCAGGACAGGTACTTGTTCCTGTTTGACAAGGTGGTCATCGTCTGCAAGCGGAAG
  GGCTACAGCTACGAGCTCAAGGAGATCATCGAGCTGCTGTTCCACAAGATGACCGACGAC
  CCCATGAACAACAAGGACGTCAAGAAGTCTCACGGGAAAATGTGGTCCTACGGCTTCTAC
  CTAATTCACCTTCAAGGAAAGCAGGGCTTCCAGTTTTTCTGCAAAACAGAAGATATGAAG
  AGGAAGTGGATGGAGCAGTTTGAGATGGCCATGTCAAACATCAAGCCAGACAAAGCCAAT
  GCCAACCACCACAGTTTCCAGATGTACACGTTTGACAAGACCACCAACTGCAAAGCCTGC
  AAAATGTTCCTCAGGGGCACCTTCTACCAGGGATACATGTGTACCAAGTGTGGCGTCGGG
  GCACACAAGGAGTGCCTGGAAGTGATACCTCCCTGCAAGTTCACTTCTCCTGCAGATCTG
  GACGCCTCCGGAGCGGGACCAGGTCCCAAGATGGTGGCCATGCAGAATTACCATGGCAAC
  CCAGCCCCTCCCGGGAAGCCTGTGCTGACCTTCCAGACGGGCGACGTGCTTGAGCTGCTG
  AGGGGCGACCCTGAGTCTCCGTGGTGGGAGGGTCGTCTGGTACAAACCAGGAAGTCAGGG
  TATTTCCCCAGCTCATCTGTGAAGCCCTGCCCTGTGGATGGAAGGCCGCCCATCAGCCGG
  CCGCCATCCCGGGAGATCGACTACACTGCATACCCCTGGTTTGCAGGTAACATGGAGAGG
  CAGCAGACGGACAACCTGCTCAAGTCCCACGCCAGCGGGACCTACCTGATCAGGGAGCGG
  CCTGCCGAGGCTGAGCGCTTTGCAATAAGCATCAAGTTCAATGATGAGGTGAAGCACATC
  AAGGTGGTGGAGAAGGACAACTGGATCCACATCACAGAGGCCAAGAAATTCGACAGCCTC
  CTGGAGTTGGTGGAGTACTACCAGTGCCACTCACTGAAGGAGAGCTTCAAGCAGCTGGAC
  ACCACACTCAAGTACCCCTACAAGTCCCGGGAACGTTCGGCCTCCAGGGCCTCCAGCCGG
  TCCCCAGCTTCCTGTGCTTCCTACAACTTTTCTTTTCTCAGTCCTCAGGGCCTCAGCTTT
  GCTTCTCAGGGCCCCTCCGCTCCCTTCTGGTCAGTGTTCACGCCCCGCGTCATCGGCACA
  GCTGTGGCCAGGTATAACTTTGCCGCCCGAGATATGAGGGAGCTTTCGCTGCGGGAGGGT
  GACGTGGTGAGGATCTACAGCCGCATCGGCGGAGACCAGGGCTGGTGGAAGGGCGAGACC
  AACGGACGGATTGGCTGGTTTCCTTCAACGTACGTAGAAGAGGAGGGCATCCAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001134398
• ORF Size: 2637 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001134398.1, NP_001127870.1
• RefSeq Size: 4865
• RefSeq ORF: 2637
• Locus ID: 7410
• Protein Families: Druggable Genome
• Protein Pathways: B cell receptor signaling pathway, Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, T cell receptor signaling pathway
• Gene Summary: VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1).