NSMAF (NM_001144772) Human Untagged Clone

CAT#: SC326295

NSMAF (untagged)-Human neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NSMAF
• Synonyms: FAN; GRAMD5
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001144772, the custom clone sequence may differ by one or more nucleotides
  ATGACGGGCCAGGCCAGATTCCACCGCGGAGCCGAGGCATGCCGAGCTATCCGGCAGTGC
  AGGTCCCGGCGGCCGCGGGCAGCTCACCCGGAAGGCCGCGCGGGGTCCGGGCGTGGATCC
  CGGCACGCGAGCCCGGGCGTTCGCAGGGGAGGATTTTCCTTGCTGCTGCTTAACTTGGAG
  GAGTACTACTTTGAACAGCATAGAGCCAATCACATTTTGCACAAGGGCAGTCACCATGAA
  AGGAAAATCAGAGGCTCCTTAAAAATATGTTCAAAATCGGTGATTTTTGAACCAGATTCA
  ATATCCCAGCCCATCATCAAGATTCCTTTGAGAGACTGTATAAAAATAGGAAAGCATGGA
  GAAAATGGAGCCAATAGACACTTCACAAAGGCAAAATCTGGGGGTATTTCACTCATTTTC
  AGTCAGGTATATTTCATTAAAGAACATAATGTTGTTGCACCATATAAAATAGAAAGGGGC
  AAAATGGAATATGTTTTTGAATTGGATGTTCCCGGGAAAGTGGAAGATGTTGTGGAGACG
  TTGCTTCAGCTTCACAGAGCATCCTGCCTTGACAAATTGGGTGACCAAACCGCCATGATA
  ACAGCTATTTTGCAGTCTCGTTTAGCTAGAACATCATTTGACAAAAACAGGTTCCAAAAC
  ATTTCTGAAAAGCTGCACATGGAATGCAAAGCAGAAATGGTGACGCCTCTGGTGACTAAT
  CCTGGACACGTGTGCATCACGGACACAAACCTGTATTTTCAGCCCCTCAACGGCTACCCG
  AAACCTGTGGTCCAGATAACACTCCAAGATGTCCGCCGCATCTACAAAAGGAGGCACGGC
  CTCATGCCTCTGGGCTTGGAAGTATTTTGCACAGAAGATGATCTGTGTTCCGACATCTAC
  CTAAAGTTCTATGAACCTCAAGATAGAGATGATCTCTATTTTTACATTGCCACATACCTA
  GAGCACCATGTGGCGGAGCACACTGCTGAGAGCTACATGCTGCAGTGGCAGCGTGGACAC
  CTTTCCAACTATCAGTACCTCCTTCACCTCAACAACCTGGCCGACCGCAGCTGCAACGAC
  CTCTCCCAGTACCCTGTGTTTCCATGGATAATACATGATTATTCCAGCTCAGAACTAGAT
  TTGTCAAATCCAGGAACCTTCCGGGATCTCAGTAAGCCAGTAGGGGCCCTAAATAAGGAA
  CGGCTGGAGAGACTACTGACACGCTACCAGGAAATGCCTGAACCAAAGTTCATGTATGGG
  AGTCACTACTCTTCCCCGGGTTATGTACTTTTTTATCTTGTTAGGATTGCACCAGAGTAT
  ATGCTGTGCCTGCAGAATGGAAGATTTGATAATGCAGATAGAATGTTCAACAGTATTGCA
  GAAACTTGGAAAAACTGTCTGGATGGTGCAACGGATTTTAAAGAGTTAATTCCAGAATTC
  TATGGTGATGATGTGAGCTTTCTAGTCAATAGCCTGAAGTTGGATTTGGGAAAGAGACAA
  GGAGGACAGATGGTTGACGACGTGGAGCTTCCCCCTTGGGCTTCCAGTCCCGAGGACTTT
  CTCCAGAAGAGCAAAGATGCATTGGAAAGCAATTATGTGTCTGAACACCTTCACGAGTGG
  ATTGATCTAATATTTGGCTACAAACAAAAAGGGAGTGATGCAGTTGGGGCCCATAATGTA
  TTTCATCCCCTGACCTATGAAGGAGGTGTAGACTTGAACAGCATCCAGGATCCTGATGAG
  AAGGTAGCCATGCTTACGCAAATCTTGGAATTTGGGCAGACACCAAAACAACTATTTGTG
  ACACCACATCCTCGAAGGATCACCCCAAAGTTTAAAAGTTTGTCCCAGACCTCCAGTTAT
  AATGCTTCTATGGCAGATTCCCCAGGTGAAGAGTCTTTTGAAGACCTGACCGAAGAAAGC
  AAAACACTGGCCTGGAATAACATCACCAAACTGCAGTTACACGAGCACTATAAAATCCAC
  AAAGAAGCAGTTACTGGAATCACGGTCTCTCGCAATGGATCTTCAGTATTCACAACATCC
  CAAGATTCCACCTTGAAGATGTTTTCTAAAGAATCAAAAATGCTACAAAGAAGTATATCA
  TTTTCAAATATGGCTTTATCGTCTTGTTTACTTTTACCAGGAGATGCCACTGTCATAACT
  TCTTCATGGGATAATAATGTCTATTTTTATTCCATAGCATTTGGAAGACGCCAGGACACG
  TTAATGGGACATGATGATGCTGTTAGTAAGATCTGTTGGCATGACAACAGGCTATATTCT
  GCATCGTGGGACTCTACAGTGAAGGTGTGGTCTGGTGTTCCTGCAGAGATGCCAGGCACC
  AAAAGACACCACTTTGACTTGCTGGCCGAGCTGGAACATGATGTCAGTGTAGATACAATC
  AGTTTAAATGCTGCAAGCACACTGTTAGTTTCCGGCACCAAAGAAGGCACAGTGAATATT
  TGGGACCTCACAACGGCCACCTTAATGCACCAGATTCCATGCCATTCAGGGATTGTATGT
  GACACTGCTTTTAGCCCAGATAGTCGCCATGTCCTCAGCACAGGAACAGATGGCTGTCTT
  AATGTCATTGATGTGCAGACAGGAATGCTCATCTCCTCCATGACATCAGATGAGCCCCAG
  AGGTGCTTTGTCTGGGATGGAAATTCCGTTTTATCTGGCAGTCAGTCTGGTGAACTGCTC
  GTTTGGGACCTCCTTGGAGCAAAAATCAGTGAGAGAATACAGGGCCACACAGGTGCTGTG
  ACATGTATATGGATGAATGAACAGTGTAGCAGTATCATCACAGGAGGGGAAGACAGACAA
  ATTATATTCTGGAAATTGCAGTAT
  
• Restriction Sites: Please inquire
• ACCN: NM_001144772
• ORF Size: 2847 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001144772.1, NP_001138244.1
• RefSeq Size: 3522
• RefSeq ORF: 2847
• Locus ID: 8439
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (2) uses an alternate exon in the 5' UTR and coding region. Isoform 2 has a longer N-terminus, compared to isoform 1.