SLC4A4 (NM_001134742) Human Untagged Clone

CAT#: SC326337

SLC4A4 (untagged)-Human solute carrier family 4, sodium bicarbonate cotransporter, member 4 (SLC4A4), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC4A4
• Synonyms: hhNMC; HNBC1; KNBC; kNBC1; NBC1; NBC2; NBCe1-A; pNBC; SLC4A5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001134742, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGATGAAGCTGTCCTGGACAGAGGGGCTTCCTTCCTCAAGCATGTGTGTGATGAAGAAGAAGTAG
  AAGGCCACCATACCATTTACATCGGAGTCCATGTGCCGAAGAGTTACAGGAGAAGGAGACGTCACAAGAG
  AAAGACAGGGCACAAAGAAAAGAAGGAAAAGGAGAGAATCTCTGAGAACTACTCTGACAAATCAGATATT
  GAAAATGCTGATGAATCCAGCAGCAGCATCCTAAAACCTCTCATCTCTCCTGCTGCAGAACGCATCCGAT
  TCATCTTGGGAGAGGAGGATGACAGCCCAGCTCCCCCTCAGCTCTTCACGGAACTGGATGAGCTGCTGGC
  CGTGGATGGGCAGGAGATGGAGTGGAAGGAAACAGCCAGGTGGATCAAGTTTGAAGAAAAAGTGGAACAG
  GGTGGGGAAAGATGGAGCAAGCCCCATGTGGCCACATTGTCCCTTCATAGTTTATTTGAGCTGAGGACAT
  GTATGGAGAAAGGATCCATCATGCTTGATCGGGAGGCTTCTTCTCTCCCACAGTTGGTGGAGATGATTGT
  TGACCATCAGATTGAGACAGGCCTATTGAAACCTGAACTTAAGGATAAGGTGACCTATACTTTGCTCCGG
  AAGCACCGGCATCAAACCAAGAAATCCAACCTTCGGTCCCTGGCTGACATTGGGAAGACAGTCTCCAGTG
  CAAGTAGGATGTTTACCAACCCTGATAATGGTAGCCCAGCCATGACCCATAGGAATCTGACTTCCTCCAG
  TCTGAATGACATTTCTGATAAACCGGAGAAGGACCAGCTGAAGAATAAGTTCATGAAAAAATTGCCACGT
  GATGCAGAAGCTTCCAACGTGCTTGTTGGGGAGGTTGACTTTTTGGATACTCCTTTCATTGCCTTTGTTA
  GGCTACAGCAGGCTGTCATGCTGGGTGCCCTGACTGAAGTTCCTGTGCCCACAAGGTTCTTGTTCATTCT
  CTTAGGTCCTAAGGGGAAAGCCAAGTCCTACCACGAGATTGGCAGAGCCATTGCCACCCTGATGTCTGAT
  GAGGTGTTCCATGACATTGCTTATAAAGCAAAAGACAGGCACGACCTGATTGCTGGTATTGATGAGTTCC
  TAGATGAAGTCATCGTCCTTCCACCTGGGGAATGGGATCCAGCAATTAGGATAGAGCCTCCTAAGAGTCT
  TCCATCCTCTGACAAAAGAAAGAATATGTACTCAGGTGGAGAGAATGTTCAGATGAATGGGGATACGCCC
  CATGATGGAGGTCACGGAGGAGGAGGACATGGGGATTGTGAAGAATTGCAGCGAACTGGACGGTTCTGTG
  GTGGACTAATTAAAGACATAAAGAGGAAAGCGCCATTTTTTGCCAGTGATTTTTATGATGCTTTAAATAT
  TCAAGCTCTTTCGGCAATTCTCTTCATTTATCTGGCAACTGTAACTAATGCTATCACTTTTGGAGGACTG
  CTTGGGGATGCCACTGACAACATGCAGGGCGTGTTGGAGAGTTTCCTGGGCACTGCTGTCTCTGGAGCCA
  TCTTTTGCCTTTTTGCTGGTCAACCACTCACTATTCTGAGCAGCACCGGACCTGTCCTAGTTTTTGAGAG
  GCTTCTATTTAATTTCAGCAAGGACAATAATTTTGACTATTTGGAGTTTCGCCTTTGGATTGGCCTGTGG
  TCCGCCTTCCTATGTCTCATTTTGGTAGCCACTGATGCCAGCTTCTTGGTTCAATACTTCACACGTTTCA
  CGGAGGAGGGCTTTTCCTCTCTGATTAGCTTCATCTTTATCTATGATGCTTTCAAGAAGATGATCAAGCT
  TGCAGATTACTACCCCATCAACTCCAACTTCAAAGTGGGCTACAACACTCTCTTTTCCTGTACCTGTGTG
  CCACCTGACCCAGCTAATATCTCAATATCTAATGACACCACACTGGCCCCAGAGTATTTGCCAACTATGT
  CTTCTACTGACATGTACCATAATACTACCTTTGACTGGGCATTTTTGTCGAAGAAGGAGTGTTCAAAATA
  CGGAGGAAACCTCGTCGGGAACAACTGTAATTTTGTTCCTGATATCACACTCATGTCTTTTATCCTCTTC
  TTGGGAACCTACACCTCTTCCATGGCTCTGAAAAAATTCAAAACTAGTCCTTATTTTCCAACCACAGCAA
  GAAAACTGATCAGTGATTTTGCCATTATCTTGTCCATTCTCATCTTTTGTGTAATAGATGCCCTAGTAGG
  CGTGGACACCCCAAAACTAATTGTGCCAAGTGAGTTCAAGCCAACAAGTCCAAACCGAGGTTGGTTCGTT
  CCACCGTTTGGAGAAAACCCCTGGTGGGTGTGCCTTGCTGCTGCTATCCCGGCTTTGTTGGTCACTATAC
  TGATTTTCATGGACCAACAAATTACAGCTGTGATTGTAAACAGGAAAGAACATAAACTCAAGAAAGGAGC
  AGGGTATCACTTGGATCTCTTTTGGGTGGCCATCCTCATGGTTATATGCTCCCTCATGGCTCTTCCGTGG
  TATGTAGCTGCTACGGTCATCTCCATTGCTCACATCGACAGTTTGAAGATGGAGACAGAGACTTCTGCAC
  CTGGAGAACAACCAAAGTTTCTAGGAGTGAGGGAACAAAGAGTCACTGGAACCCTTGTGTTTATTCTGAC
  TGGTCTGTCAGTCTTTATGGCTCCCATCTTGAAGTTTATACCCATGCCTGTACTCTATGGTGTGTTCCTG
  TATATGGGAGTAGCATCCCTTAATGGTGTGCAGTTCATGGATCGTCTGAAGCTGCTTCTGATGCCTCTGA
  AGCATCAGCCTGACTTCATCTACCTGCGTCATGTTCCTCTGCGCAGAGTCCACCTGTTCACTTTCCTGCA
  GGTGTTGTGTCTGGCCCTGCTTTGGATCCTCAAGTCAACGGTGGCTGCTATCATTTTTCCAGTAATGATC
  TTGGCACTTGTAGCTGTCAGAAAAGGCATGGACTACCTCTTCTCCCAGCATGACCTCAGCTTCCTGGATG
  ATGTCATTCCAGAAAAGGACAAGAAAAAGAAGGAGGATGAGAAGAAAAAGAAAAAGAAGAAGGGAAGTCT
  GGACAGTGACAATGATGATGAGAAAGATCACCAACATTCCTTGAACGCCACACATCATGCTGATAAAATT
  CCTTTCCTTCAGTCACTCGGTATGCCAAGTCCTCCTAGAACTCCAGTAAAAGTTGTGCCTCAAATTAGAA
  TAGAACTTGAACCTGAAGACAATGATTATTTCTGGAGGAGCAAGGGAACAGAAACTACATTGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001134742
• ORF Size: 3285 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001134742.1, NP_001128214.1
• RefSeq Size: 7596
• RefSeq ORF: 3285
• Locus ID: 8671
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (3) lacks an alternate exon in the 3' coding region that results in a frameshift, compared to variant 1. It encodes isoform 3 which has a longer and distinct C-terminus compared to isoform 1.