p114RhoGEF (ARHGEF18) (NM_001130955) Human Untagged Clone

CAT#: SC326348

ARHGEF18 (untagged)-Human Rho/Rac guanine nucleotide exchange factor (GEF) 18 (ARHGEF18), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARHGEF18
• Synonyms: P114-RhoGEF; p114RhoGEF; RP78; SA-RhoGEF
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001130955, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTCACAGTGGGGACCAATATCCTGCCCTCCAGACCCGCTGCTTCAGCCAATACAGCAAGGGAAGACG
  CAGCTCTGTTTTCTAGAAGGATCCCACCGAGGCATAAAAACGGCGCAGCCCAGCCTGGCGCCGCGCCGGG
  TCCCGGAGCCCCGGGCGCGAACATGGGGAATGCGCACTCCAAAAGCGGGGACAGGCACAGCGCGCTCCCC
  GGCCGCCCCGAGCTGTCTTTTTACGGCTCTTTCCCCAGGAAATGGAGCGAGAACGTCTTCTTGGATAACG
  AGCTGCTGACCTCCAAGATCCTGTCTGTGCTGCGGCCGCAGTCGGAGCGGGGCTTCCGCGCCGGGGACCT
  CCGCTACCCGACCCACTTTCTCAGCACCAACTCTGTCCTTGCCTCTGTCACAGCCTCGCTCAAGGAGCAC
  CCCCGGGGCACCCTCCTGTCCGATGGCAGCCCGGCCCTGTCCAGGAATGTCGGTATGACGGTCTCTCAGA
  AAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACGCAACTCGGACCAATCACAGGAGAGAT
  GGATGAAGCCGATTCTGCGTTTTTAAAATTTAAGCAGACAGCTGATGACTCTCTGTCCCTTACATCTCCA
  AACACCGAGTCCATTTTTGTAGAAGATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCC
  ACGAGTTTGAAGCTGAGTCCTGGAGCCTCGCCGTGGATGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGT
  GGTGAAAAGACAAGATGTCCTTTATGAGCTGATGCAGACAGAGGTGCACCACGTGCGGACGCTCAAGATC
  ATGCTGAAGGTGTACTCCAGGGCCCTGCAGGAGGAGCTGCAGTTCAGCAGCAAGGCCATTGGCCGCCTCT
  TCCCATGCGCTGACGACCTGCTGGAGACGCACAGCCACTTCCTCGCTCGGCTCAAGGAGCGCCGCCAGGA
  GTCCCTGGAGGAGGGCAGTGACCGGAATTATGTCATCCAGAAAATCGGCGACCTCCTGGTTCAGCAGTTT
  TCAGGTGAAAATGGGGAGAGAATGAAAGAAAAGTACGGTGTGTTTTGTAGTGGCCACAATGAAGCTGTTA
  GTCATTACAAGTTGCTGCTTCAGCAAAACAAGAAATTTCAAAACTTGATCAAGAAAATTGGCAACTTCTC
  CATCGTGCGGCGGCTTGGCGTGCAGGAGTGCATTCTCCTGGTTACACAACGCATAACCAAATACCCAGTG
  CTGGTGGAGCGCATCATCCAGAACACGGAAGCTGGCACTGAGGACTATGAAGACCTGACCCAGGCCTTGA
  ACCTCATCAAAGATATCATCTCACAAGTGGACGCCAAGGTCAGTGAGTGTGAGAAGGGCCAGCGCCTCAG
  GGAGATCGCAGGGAAGATGGACCTGAAGTCTTCCAGCAAACTCAAGAACGGGCTCACCTTCCGCAAGGAA
  GACATGCTTCAGCGGCAGCTCCACCTGGAGGGCATGCTATGCTGGAAGACCACATCAGGGCGCTTGAAAG
  ATATCCTGGCTATCCTGCTGACCGACGTACTTTTGCTGCTACAAGAAAAAGATCAGAAATACGTCTTTGC
  TTCTGTGGACTCAAAGCCACCCGTCATCTCGTTACAAAAGCTCATCGTGAGGGAAGTGGCCAACGAGGAG
  AAAGCGATGTTTCTGATCAGCGCCTCCTTGCAAGGGCCGGAGATGTATGAAATCTACACGAGCTCCAAAG
  AGGACAGGAACGCCTGGATGGCCCACATCCAAAGGGCTGTGGAGAGCTGCCCTGACGAGGAGGAGGGGCC
  CTTCAGCCTGCCCGAAGAGGAAAGGAAGGTGGTCGAGGCCCGCGCCACGAGACTCCGGGACTTTCAAGAG
  CGGTTGAGCATGAAAGACCAGCTGATCGCACAGAGCCTCCTAGAGAAACAGCAGATCTACCTGGAGATGG
  CCGAGATGGGCGGCCTCGAAGACCTGCCCCAGCCCCGAGGCCTATTCCGTGGAGGGGACCCATCCGAGAC
  CCTGCAGGGGGAGCTAATTCTCAAGTCGGCCATGAGCGAGATCGAGGGCATCCAGAGCCTGATCTGCAGG
  CAGCTGGGCAGCGCCAACGGCCAGGCGGAAGACGGAGGCAGCTCCACAGGCCCGCCCAGGAGGGCTGAGA
  CCTTCGCGGGCTACGACTGCACAAACAGCCCCACCAAGAATGGCAGTTTCAAGAAGAAAGTCAGCAGCAC
  TGACCCCAGGCCCCGAGACTGGCGAGGCCCCCCAAACAGCCCGGACTTGAAGCTCAGTGACAGTGACATT
  CCTGGGAGCTCTGAGGAATCGCCGCAGGTGGTGGAGGCGCCAGGCACGGAATCCGATCCCCGTCTGCCCA
  CCGTCCTGGAGTCGGAGCTTGTCCAGCGGATCCAGACACTGTCCCAGCTGCTCCTGAACCTTCAGGCGGT
  AATCGCCCACCAGGACAGCTATGTGGAGACGCAGCGGGCTGCCATCCAGGAGCGGGAGAAGCAGTTCCGG
  CTGCAGTCGACGCGTGGGAACCTGCTGCTGGAGCAGGAGCGGCAACGCAACTTCGAGAAGCAGCGGGAGG
  AGCGCGCGGCCCTGGAGAAGCTGCAGAGCCAGCTGCGGCACGAGCAGCAGCGCTGGGAGCGCGAGCGCCA
  GTGGCAGCACCAGGAGCTGGAGCGTGCGGGCGCGCGGCTGCAGGAGCGCGAGGGCGAGGCGCGGCAGCTA
  CGCGAGCGGCTGGAGCAGGAGCGGGCCGAGCTGGAGCGCCAGCGCCAGGCCTACCAGCACGACCTGGAGC
  GGCTGCGCGAGGCCCAGCGTGCCGTGGAGCGCGAGCGGGAGCGCCTGGAGCTGCTGCGCCGCCTCAAGAA
  GCAGAACACCGCGCCAGGCGCGCTGCCGCCCGACACACTGGCCGAGGCCCAGCCCCCAAGCCACCCTCCC
  AGCTTCAACGGGGAAGGGCTGGAGGGCCCTCGTGTGAGCATGCTGCCATCCGGCGTGGGGCCAGAGTACG
  CAGAGCGCCCCGAGGTGGCTCGCCGGGACAGCGCCCCCACCGAGAACCGGCTGGCCAAGAGCGATGTGCC
  CATCCAGCTGCTCAGCGCCACCAACCAGTTCCAGAGGCAGGCGGCCGTGCAGCAGCAGATCCCCACCAAG
  CTGGCGGCCTCCACCAAGGGTGGCAAGGACAAGGGCGGCAAGAGCAGGGGCTCTCAGCGCTGGGAGAGCT
  CAGCGTCCTTCGACCTGAAGCAGCAGCTGCTGCTCAACAAGCTCATGGGGAAAGATGAGAGCACCTCACG
  GAACCGCCGCTCGCTGAGCCCTATCCTGCCCGGCAGACACAGTCCTGCGCCCCCACCAGACCCTGGCTTC
  CCCGCCCCGAGCCCACCGCCAGCTGACAGCCCCTCCGAGGGCTTCTCTCTCAAGGCCGGGGGCACAGCCC
  TCCTGCCCGGGCCCCCAGCTCCCTCGCCACTGCCGGCCACACCACTCAGCGCCAAGGAGGACGCCAGCAA
  AGAAGACGTCATCTTCTTCTAA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001130955
• ORF Size: 3522 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001130955.1, NP_001124427.1
• RefSeq Size: 5773
• RefSeq ORF: 3522
• Locus ID: 23370
• Gene Summary: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GEF family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2018]
  Transcript Variant: This variant (2) differs in the 5' UTR and the 5' coding region, compared to variant 1. The resulting isoform (b) contains a distinct N-terminus, compared to isoform a.