PCDH15 (NM_001142771) Human Untagged Clone

CAT#: SC326396

PCDH15 (untagged)-Human protocadherin-related 15 (PCDH15), transcript variant K

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDH15
• Synonyms: CDHR15; DFNB23; USH1F
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001142771, the custom clone sequence may differ by one or more nucleotides
  ATGTTTCGACAGTTTTATCTCTGGACATGTTTAGCTTCAGGGATCATCCTGGGCTCTCTC
  TTTGAAATCTGCTTGGGCCAGTATGATGATGACTGGCAATATGAGGATTGCAAACTAGCT
  AGGGGAGGACCACCAGCTACCATAGTTGCTATTGATGAAGAAAGTCGGAATGGTACAATT
  CTGGTGGACAACATGCTGATCAAAGGGACTGCTGGAGGACCAGACCCCACCATAGAACTT
  TCTTTAAAGGATAATGTGGATTACTGGGTGTTGATGGATCCTGTTAAGCAAATGCTTTTC
  CTGAACAGCACCGGAAGAGTTCTGGATAGAGATCCACCGATGAACATACACTCCATTGTG
  GTGCAGGTCCAGTGCATCAACAAAAAAGTGGGCACTATTATCTACCATGAAGTGCGAATA
  GTGGTGAGAGACAGGAATGACAACTCACCCACTTTCAAGCATGAAAGCTACTATGCCACA
  GTGAATGAGCTCACTCCAGTTGGTACCACAATATTCACAGGATTTTCAGGAGACAATGGA
  GCTACAGATATAGATGATGGACCAAATGGACAGATAGAGTATGTTATTCAGTATAATCCA
  GATGATCCGACATCCAATGACACCTTTGAAATTCCCCTAATGTTGACTGGAAATATAGTG
  TTAAGGAAGAGGCTCAACTATGAAGATAAGACTCGCTACTTTGTCATAATCCAAGCTAAT
  GACCGTGCCCAAAATCTGAATGAGAGGCGAACCACCACCACCACTCTCACAGTGGATGTT
  CTGGATGGAGATGACTTGGGTCCAATGTTTCTTCCTTGTGTCCTTGTGCCAAACACTCGT
  GATTGCCGTCCACTCACTTATCAAGCTGCCATACCTGAGTTGAGAACTCCGGAAGAACTG
  AACCCCATTATTGTTACGCCACCAATCCAAGCCATTGATCAGGACCGGAATATTCAACCG
  CCATCAGATAGGCCAGGAATCCTCTATTCCATCCTTGTTGGGACTCCTGAGGATTACCCA
  CGATTTTTCCATATGCATCCTAGGACAGCAGAACTTAGTCTCCTGGAGCCAGTAAACAGA
  GACTTTCACCAGAAATTTGATTTGGTTATTAAGGCTGAACAAGACAATGGTCATCCTCTT
  CCTGCCTTTGCCGGTCTACACATTGAAATACTGGATGAAAACAATCAAAGTCCATATTTT
  ACAATGCCCAGTTATCAAGGCTATATCCTGGAATCTGCCCCAGTGGGAGCAACCATTTCG
  GACAGTCTCAATTTGACTTCACCTTTAAGAATAGTAGCTCTGGACAAGGACATAGAAGAT
  ACAAAAGACCCAGAGCTTCACCTTTTTCTGAATGACTACACCTCAGTCTTCACCGTCACA
  CAGACTGGTATTACTCGCTACCTCACCTTACTTCAACCAGTGGACAGGGAAGAACAGCAA
  ACTTACACCTTTTCGATAACAGCATTTGATGGTGTACAAGAAAGTGAGCCAGTCATCGTC
  AATATTCAAGTGATGGATGCAAATGATAACACGCCAACCTTCCCTGAAATATCCTATGAT
  GTGTATGTTTATACAGACATGAGACCTGGGGACAGTGTCATACAGCTCACTGCAGTCGAC
  GCAGACGAAGGGTCAAATGGGGAGATCACATATGAAATCCTTGTTGGGGCTCAGGGAGAC
  TTCATCATCAATAAAACAACAGGGCTTATCACCATCGCTCCAGGGGTGGAAATGATAGTC
  GGGCGGACTTACGCACTCACGGTCCAAGCAGCGGATAATGCTCCTCCTGCAGAGCGAAGG
  AACTCCATCTGCACTGTGTATATTGAAGTGCTTCCACCAAATAATCAAAGCCCTCCTCGC
  TTCCCACAGCTGATGTATAGCCTTGAAATTAGTGAAGCCATGAGGGTTGGTGCTGTTTTA
  TTAAATCTACAGGCAACTGATCGAGAGGGAGACTCAATAACATATGCCATTGAGAATGGA
  GATCCTCAGAGAGTTTTTAATCTTTCAGAAACCACGGGGATTCTAACCTTAGGGAAAGCA
  CTGGACAGGGAAAGCACTGATCGCTACATTCTGATCATCACAGCTTCAGATGGCAGGCCA
  GATGGGACCTCAACTGCCACAGTAAACATAGTGGTGACAGATGTCAATGACAATGCTCCA
  GTGTTTGATCCTTATCTGCCAAGAAATTTATCTGTGGTGGAAGAAGAAGCCAATGCCTTT
  GTGGGTCAAGTAAAAGCAACAGACCCTGATGCTGGAATAAATGGTCAAGTGCACTACAGT
  TTGGGTAACTTTAATAATCTTTTTCGTATCACATCCAATGGGAGCATTTACACAGCAGTG
  AAGCTTAACAGAGAAGTCAGGGACTACTATGAACTTGTTGTTGTGGCAACAGATGGAGCA
  GTACACCCTCGTCATTCAACTCTAACCTTGGCCATCAAGGTTTTGGACATTGATGATAAC
  AGTCCTGTGTTCACCAATTCAACATACACTGTCCTTGTTGAAGAGAATTTGCCAGCTGGG
  ACTACCATCCTTCAAATAGAGGCCAAAGATGTCGACCTTGGAGCAAATGTGTCTTACCGG
  ATAAGAAGCCCAGAAGTGAAGCACTTTTTTGCACTACATCCATTTACAGGAGAACTATCG
  CTTTTAAGGAGTTTAGATTATGAGGCATTTCCAGACCAAGAAGCAAGTATCACTTTTCTG
  GTAGAGGCCTTTGATATTTATGGAACAATGCCACCTGGTATTGCTACTGTCACAGTGATT
  GTAAAGGATATGAATGATTATCCTCCTGTCTTTAGTAAACGAATATACAAAGGGATGGTG
  GCTCCGGATGCAGTCAAGGGTACACCTATCACAACAGTTTATGCTGAAGATGCAGACCCT
  CCTGGATTACCTGCAAGTCGTGTGAGGTATAGAGTAGATGATGTACAGTTTCCTTACCCT
  GCCAGTATTTTTGAAGTGGAAGAAGATTCTGGAAGAGTAATAACACGAGTCAATCTTAAT
  GAAGAACCTACAACAATTTTTAAGTTGGTGGTGGTTGCTTTTGATGATGGGGAGCCTGTG
  ATGTCCAGCAGTGCCACAGTGAAGATTCTTGTCTTACATCCTGGTGAGATCCCACGCTTC
  ACACAGGAGGAATATAGACCTCCTCCAGTAAGTGAACTTGCCACCAAAGGGACCATGGTT
  GGTGTAATTTCTGCTGCTGCCATTAATCAAAGTATTGTGTACTCCATTGTTTCAGGAAAT
  GAAGAAGATACATTTGGAATTAATAACATCACAGGTGTTATCTATGTGAATGGACCTCTG
  GATTATGAGACCAGGACAAGCTATGTACTTCGAGTCCAAGCTGATTCCCTGGAAGTGGTC
  CTTGCCAATCTCCGAGTTCCTTCAAAAAGCAATACAGCTAAAGTATACATTGAGATTCAG
  GATGAAAATAATCATCCCCCAGTGTTTCAGAAAAAATTCTACATCGGAGGTGTATCTGAA
  GATGCAAGAATGTTTACTTCTGTACTCAGAGTGAAGGCTACTGATAAAGATACTGGCAAT
  TATAGTGTCATGGCCTACAGACTCATAATACCACCAATTAAAGAGGGAAAAGAAGGATTT
  GTAGTGGAAACATATACAGGGCTTATCAAAACTGCTATGCTCTTCCATAATATGAGGAGA
  TCCTACTTCAAGTTTCAAGTTATTGCAACTGACGACTATGGGAAGGGACTGAGCGGCAAA
  GCCGATGTACTCGTCTCCGTGGTCAATCAGCTGGATATGCAAGTCATTGTTTCCAATGTG
  CCTCCTACTCTAGTGGAAAAAAAGATAGAAGATCTTACAGAGATCTTGGATCGCTATGTT
  CAGGAACAAATTCCTGGTGCCAAGGTCGTAGTGGAGTCCATTGGAGCTCGCCGGCATGGA
  GATGCCTTTTCCCTAGAAGATTACACCAAATGTGACTTGACTGTCTATGCAATTGACCCC
  CAAACCAACAGAGCCATCGATAGAAATGAGCTTTTTAAATTTTTGGATGGCAAACTACTT
  GATATCAATAAAGACTTTCAGCCGTATTATGGGGAAGGAGGACGCATTCTGGAGATCCGG
  ACTCCAGAGGCAGTGACCAGCATTAAAAAGAGAGGAGAAAGTCTAGGATACACAGAAGGG
  GCCTTGTTGGCTCTGGCCTTCATCATCATCCTCTGCTGCATTCCTGCCATCTTGGTGGTT
  TTGGTCAGCTACAGACAGTTTAAAGTACGTCAAGCTGAGTGTACAAAGACTGCACGAATT
  CAGGCCGCATTACCCGCGGCTAAACCAGCAGTGCCGGCTCCTGCACCAGTGGCAGCGCCC
  CCGCCGCCGCCGCCGCCTCCGCCAGGTGCGCATCTCTATGAAGAACTTGGAGACAGCTCA
  ATGCATAAGTATGAAATGCCTCAATATGGGAGTCGCCGTCGATTGTTACCACCAGCTGGA
  CAGGAGGAATATGGTGAGGTGGTTGGTGAAGCTGAGGAAGAATATGAGGAGGAAGAGTGG
  GCAAGAAAAAGAATGATCAAGTTAGTTGTTGATCGAGAGTATGAAACCAGCTCAACTGGA
  GAAGACAGTGCTCCTGAATGTCAGAGAAACCGTCTTCACCATCCTAGTATCCACAGTAAT
  ATCAACGGCAATATATATATTGCACAGAATGGTTCTGTGGTGAGAACCCGCCGTGCCTGC
  CTCACGGACAACTTAAAAGTTGCTTCCCCTGTTCGACTGGGAGGGCCCTTTAAGAAACTA
  GACAAGTTGGCAGTGACACATGAGGAGAATGTACCTCTGAACACATTATCAAAGGGGCCA
  TTTTCTACTGAAAAAATGAATGCAAGACCAACTCTGGTTACATTTGCCCCTTGCCCTGTG
  GGGACTGACAATACAGCGGTGAAGCCACTAAGGAACAGGCTGAAAAGCACAGTTGAACAG
  GAGTCCATGATTGACAGTAAGAACATCAAGGAGGCTTTGGAATTTCATAGTGACCACACA
  CAGTCTGATGATGAAGAGCTTTGGATGGGCCCCTGGAACAACCTCCATATACCAATGACA
  AAACTG
  
• Restriction Sites: Please inquire
• ACCN: NM_001142771
• ORF Size: 5049 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001142771.1, NP_001136243.1
• RefSeq Size: 9252
• RefSeq ORF: 5049
• Locus ID: 65217
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. [provided by RefSeq, Dec 2008]
  Transcript Variant: This variant (K) has a distinct 3' splice pattern, compared to variant A. The resulting isoform (CD3-1) has a distinct and longer C-terminus, compared to isoform CD1-1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on orthologous data.