Girdin (CCDC88A) (NM_001135597) Human Untagged Clone

CAT#: SC326406

CCDC88A (untagged)-Human coiled-coil domain containing 88A (CCDC88A), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCDC88A
• Synonyms: APE; GIRDIN; GIV; GRDN; HkRP1; KIAA1212; PEHO; PEHOL
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001135597, the custom clone sequence may differ by one or more nucleotides
  ATGGAGAACGAAATTTTTACTCCCCTTCTGGAGCAGTTCATGACCAGCCCTTTGGTCACT
  TGGGTTAAAACGTTTGGACCTCTGGCCGCAGGAAATGGGACCAACCTTGATGAATATGTG
  GCTTTGGTGGATGGGGTATTCTTGAACCAGGTCATGCTCCAAATTAATCCTAAATTGGAG
  AGTCAGAGAGTAAATAAAAAAGTCAATAATGATGCCTCACTTAGAATGCACAATCTATCC
  ATTTTGGTGAGACAGATAAAATTTTATTACCAGGAGACTTTGCAGCAATTGATCATGATG
  TCGTTGCCAAATGTCTTAATCATTGGCAAAAATCCCTTTTCTGAACAAGGCACAGAAGAA
  GTTAAAAAACTGCTTTTACTTTTATTGGGTTGTGCAGTTCAGTGTCAGAAAAAAGAGGAA
  TTTATTGAAAGAATTCAAGGTTTAGATTTTGATACAAAAGCAGCGGTTGCCGCACATATT
  CAAGAGGTAACTCATAATCAGGAAAATGTGTTTGACCTGCAATGGATGGAAGTGACTGAT
  ATGTCGCAGGAGGACATAGAACCACTCTTGAAAAATATGGCATTGCATCTAAAAAGACTT
  ATAGATGAGAGAGATGAACATTCAGAGACTATCATAGAACTCTCTGAAGAGCGGGATGGT
  CTCCATTTTCTACCCCATGCCTCTTCATCTGCACAGTCACCCTGTGGTTCTCCAGGCATG
  AAGCGAACAGAAAGTCGACAACATCTGTCGGTGGAACTGGCAGATGCTAAAGCCAAGATA
  AGAAGGCTTAGGCAGGAATTGGAGGAAAAGACTGAGCAGTTGTTGGATTGTAAACAAGAA
  CTTGAGCAAATGGAAATAGAACTCAAAAGGCTGCAACAAGAGAACATGAATTTGCTTTCG
  GATGCTCGCTCTGCCAGAATGTACCGAGATGAATTAGATGCACTTCGAGAGAAAGCAGTC
  AGAGTCGATAAGCTTGAAAGTGAAGTCAGCAGATATAAAGAGAGACTACATGATATTGAA
  TTTTATAAGGCAAGAGTTGAGGAATTAAAAGAAGACAATCAAGTTTTATTAGAAACAAAA
  ACCATGTTGGAAGACCAACTAGAGGGAACTCGTGCTCGTTCTGATAAATTACATGAATTA
  GAAAAAGAGAACTTACAACTGAAAGCTAAACTTCATGATATGGAAATGGAACGAGATATG
  GATAGAAAAAAGATTGAAGAATTAATGGAAGAAAATATGACTTTGGAAATGGCACAGAAA
  CAAAGTATGGATGAATCATTACATCTTGGCTGGGAACTGGAACAGATATCCAGAACTAGT
  GAACTTTCCGAAGCACCCCAGAAATCCCTGGGCCATGAGGTGAATGAGTTGACATCAAGT
  AGATTATTGAAGCTAGAGATGGAAAATCAAAGTTTGACAAAAACCGTAGAAGAGCTTCGG
  ACTACTGTGGATTCTGTAGAAGGCAATGCTTCCAAAATCCTGAAAATGGAAAAAGAAAAT
  CAAAGGCTCAGTAAAAAGGTTGAGATTCTTGAAAATGAGATTGTTCAAGAAAAGCAAAGT
  CTTCAGAATTGTCAGAATTTAAGCAAGGATCTAATGAAGGAGAAAGCTCAGCTTGAAAAA
  ACAATAGAAACACTGAGAGAAAATTCAGAGAGACAGATTAAGATACTGGAACAGGAAAAT
  GAACATCTGAATCAAACAGTGTCTTCCTTAAGGCAGCGGTCCCAGATAAGTGCAGAAGCA
  AGAGTGAAAGACATTGAAAAAGAAAACAAAATTCTTCATGAATCTATCAAAGAAACAAGT
  AGCAAGCTAAGCAAGATTGAATTTGAAAAAAGACAAATTAAAAAAGAATTGGAACATTAT
  AAAGAAAAAGGAGAACGAGCTGAAGAACTTGAAAATGAATTGCATCATCTTGAAAAAGAA
  AATGAATTATTACAGAAAAAAATAACTAATTTAAAAATTACTTGTGAAAAAATTGAGGCC
  TTAGAACAAGAAAATTCAGAGCTAGAAAGAGAAAATAGAAAATTAAAAAAAACATTGGAT
  AGCTTTAAAAATCTGACCTTTCAGTTAGAATCCCTAGAAAAAGAGAATTCCCAACTTGAT
  GAGGAAAACTTAGAACTGCGAAGGAATGTAGAATCTTTGAAGTGTGCAAGCATGAAAATG
  GCTCAGCTACAGCTAGAAAACAAAGAACTGGAAAGTGAAAAAGAGCAACTTAAGAAGGGT
  TTGGAGCTCCTGAAAGCATCTTTCAAGAAAACAGAACGCTTAGAAGTTAGCTACCAGGGT
  TTAGATATAGAAAATCAAAGACTGCAAAAAACTTTAGAGAACAGCAATAAAAAAATCCAG
  CAATTAGAGAGTGAACTACAAGACTTAGAGATGGAAAATCAAACATTGCAGAAAAACCTA
  GAAGAACTAAAAATATCTAGCAAAAGACTAGAACAGCTGGAAAAAGAAAATAAATCATTA
  GAGCAAGAGACTTCTCAACTGGAAAAGGATAAGAAACAATTGGAGAAGGAAAATAAGAGA
  CTCCGACAACAAGCAGAAATTAAAGATACCACATTAGAAGAAAATAATGTGAAGATTGGA
  AATTTGGAAAAAGAAAACAAAACCCTATCCAAAGAAATTGGTATATATAAAGAATCTTGT
  GTCCGTCTGAAAGAACTAGAAAAAGAAAATAAGGAGCTTGTGAAAAGAGCAACTATTGAT
  ATAAAAACGTTGGTTACACTACGTGAGGATTTGGTGAGTGAAAAGTTGAAGACCCAACAG
  ATGAACAATGATCTCGAAAAATTAACTCATGAGCTTGAGAAGATAGGGTTAAATAAGGAG
  CGACTCTTACATGATGAACAAAGTACTGATGACAGGTATAAACTTTTGGAATCAAAATTA
  GAATCCACTCTTAAGAAGTCTCTTGAAATAAAAGAAGAAAAAATTGCTGCTTTAGAAGCT
  CGATTAGAAGAATCCACGAATTATAACCAGCAATTGCGCCAAGAACTTAAAACAGTGAAA
  AAAAATTATGAAGCTCTCAAACAGAGACAAGATGAGGAAAGGATGGTACAGAGCTCTCCT
  CCAATATCTGGTGAAGACAACAAATGGGAGCGAGAAAGTCAAGAAACGACTAGAGAACTT
  CTGAAAGTTAAAGACAGATTAATTGAAGTAGAAAGAAATAATGCTACACTGCAAGCAGAG
  AAGCAAGCGTTGAAAACTCAACTGAAGCAACTTGAGACACAGAACAATAATTTGCAGGCT
  CAGATTCTTGCACTTCAGAGGCAGACAGTGTCATTACAAGAACAGAATACCACTCTTCAA
  ACACAGAATGCCAAGCTTCAGGTTGAAAATTCCACCCTTAATTCCCAAAGTACCTCACTC
  ATGAACCAGAATGCCCAACTCCTAATCCAGCAGTCTTCCTTAGAAAATGAAAATGAATCT
  GTAATCAAAGAGCGAGAAGACCTAAAATCTCTCTATGATTCTCTGATCAAAGATCATGAA
  AAGCTGGAACTTCTTCATGAACGTCAGGCTTCAGAGTATGAATCTCTTATCTCTAAACAT
  GGAACTCTGAAGTCTGCCCACAAAAATCTTGAGGTGGAACATAGAGACCTTGAAGACCGT
  TACAATCAGTTATTAAAACAGAAAGGACAGTTGGAAGATTTGGAAAAAATGCTCAAAGTA
  GAACAGGAAAAAATGCTGCTTGAAAATAAAAATCATGAAACAGTAGCTGCAGAATACAAG
  AAACTTTGTGGTGAAAATGATAGGCTGAATCATACCTATAGTCAACTTTTAAAAGAGACT
  GAAGTTTTACAAACTGACCATAAAAATTTGAAAAGTCTTCTGAATAATTCCAAACTGGAA
  CAAACAAGATTAGAAGCTGAATTTTCAAAACTAAAGGAACAATACCAACAATTGGATATT
  ACATCAACCAAGCTGAATAACCAGTGTGAGTTGCTAAGCCAACTTAAAGGAAATTTAGAA
  GAAGAAAATCGGCATCTACTAGATCAAATTCAGACATTAATGCTACAGAACAGAACACTT
  TTGGAGCAGAATATGGAAAGCAAGGATCTTTTTCATGTTGAACAAAGACAGTACATTGAT
  AAGTTAAATGAATTAAGACGTCAGAAGGAGAAACTAGAAGAGAAAATTATGGATCAATAC
  AAATTTTATGACCCATCTCCTCCTAGAAGGAGAGGCAACTGGATTACTCTAAAAATGAGA
  AAATTGATAAAGTCTAAGAAAGATATTAATCGGGAACGCCAGAAATCTCTAACATTAACA
  CCCACCCGCTCAGACTCCAGTGAAGGATTTCTTCAGCTCCCTCATCAAGACAGTCAAGAT
  AGTTCTTCAGTAGGTTCAAACTCTTTAGAAGATGGCCAGACCTTGGGGACCAAGAAAAGC
  AGCATGGTTGCACTGAAAAGACTGCCCTTTTTGAGGAACAGACCGAAGGATAAAGACAAA
  ATGAAGGCCTGCTACCGTCGTTCCATGTCCATGAATGACCTGGTGCAGTCCATGGTCCTA
  GCAGGACAGTGGACAGGTAGTACTGAGAATTTGGAGGTTCCTGATGATATTTCAACGGGT
  AAAAGGAGAAAAGAATTGGGAGCTATGGCCTTCTCTACTACAGCCATCAACTTTTCAACT
  GTCAACTCTTCTGCAGGCTTCAGATCCAAGCAGTTGGTTAATAATAAAGATACTACATCC
  TTTGAAGACATAAGTCCACAAGGTGTTAGTGATGATTCTAGTACGGGATCAAGAGTTCAT
  GCTTCAAGACCAGCCAGCCTTGATAGTGGCAGAACATCCACTAGCAATAGCAATAATAAT
  GCTTCACTACATGAAGTCAAAGCAGGTGCAGTTAATAACCAAAGCAGGCCACAAAGCCAC
  AGCAGTGGAGAATTTAGCCTGCTTCATGACCATGAGGCTTGGTCCAGCAGTGGTAGCAGT
  CCAATCCAGTACTTGAAAAGACAGACCAGATCAAGCCCAGTGCTCCAGCACAAAATATCT
  GAAACACTGGAGAGTCGACATCACAAGATCAAAACTGGTTCCCCTGGAAGTGAAGTTGTT
  ACTCTACAACAGTTTTTGGAAGAAAGCAATAAGCTTACCTCAGTACAGATAAAGTCCTCA
  AGTCAAGAGAATCTTTTAGATGAAGTAATGAAAAGTTTGTCTGTCTCTTCTGACTTTTTG
  GGAAAAGACAAACCAGTTAGCTGTGGTCTGGCCAGGTCAGTAAGTGGAAAAACCCCAGGG
  GACTTCTATGATAGACGGACAACTAAGCCTGAGTTTTTGAGACCTGGTCCTCGAAAAACT
  GAAGATACCTACTTCATTAGTTCTGCGGGAAAACCTACACCAGGCACTCAAGGAAAAATA
  AAATTAGTAAAAGAATCTTCTCTGTCACGACAATCAAAAGATAGTAACCCTTATGCAACT
  TTACCTCGTGCAAGCAGCGTGATCTCAACTGCCGAAGGAACTACACGAAGGACAAGCATC
  CATGATTTTTTGACCAAGGACAGTAGACTGCCTATATCAGTTGATTCACCACCAGCTGCT
  GCTGACAGCAACACCACTGCAGCATCTAATGTGGACAAAGTACAAGAAAGCAGAAATTCA
  AAAAGCAGGTCTAGGGAGCAACAAAGCTCC
  
• Restriction Sites: Please inquire
• ACCN: NM_001135597
• ORF Size: 5613 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001135597.1, NP_001129069.1
• RefSeq Size: 9827
• RefSeq ORF: 5613
• Locus ID: 55704
• Gene Summary: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (1) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.