NR1D2 (NM_001145425) Human Untagged Clone

CAT#: SC326486

NR1D2 (untagged)-Human nuclear receptor subfamily 1, group D, member 2 (NR1D2), transcript variant 2, mRNA

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NR1D2
• Synonyms: BD73; EAR-1R; REVERBB; REVERBbeta; RVR
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001145425, the custom clone sequence may differ by one or more nucleotides
  ATGAAAACAAGCAAATCGAGTGCACCTGGGATGACAAAAAGTCATAGTGGTGTGACAAAA
  TTTAGTGGCATGGTTCTACTGTGTAAAGTCTGTGGGGATGTGGCGTCAGGATTCCACTAT
  GGAGTTCATGCTTGCGAAGGCTGTAAGGGTTTCTTTCGGAGAAGTATTCAACAAAACATC
  CAGTACAAGAAGTGCCTGAAGAATGAAAACTGTTCTATAATGAGAATGAATAGGAACAGA
  TGTCAGCAATGTCGCTTCAAAAAGTGTCTGTCTGTTGGAATGTCAAGAGATGCTGTTCGG
  TTTGGTCGTATTCCTAAGCGTGAAAAACAGAGGATGCTAATTGAAATGCAAAGTGCAATG
  AAGACCATGATGAACAGCCAGTTCAGTGGTCACTTGCAAAATGACACATTAGTAGAACAT
  CATGAACAGACAGCCTTGCCAGCCCAGGAACAGCTGCGACCCAAGCCCCAACTGGAGCAA
  GAAAACATCAAAAGCTCTTCTCCTCCATCTTCTGATTTTGCAAAGGAAGAAGTGATTGGC
  ATGGTGACCAGAGCTCACAAGGATACCTTTATGTATAATCAAGAGCAGCAAGAAAACTCA
  GCTGAGAGCATGCAGCCCCAGAGAGGAGAACGGATTCCCAAGAACATGGAGCAATATAAT
  TTAAATCATGATCATTGCGGCAATGGGCTTAGCAGCCATTTTCCCTGTAGTGAGAGCCAG
  CAGCATCTCAATGGACAGTTCAAAGGGAGGAATATAATGCATTACCCAAATGGTCATGCC
  ATTTGTATTGCAAATGGACATTGTATGAACTTCTCCAATGCTTATACTCAAAGAGTATGT
  GATAGAGTTCCGATAGATGGATTTTCTCAGAATGAGAACAAGAATAGTTACCTGTGCAAC
  ACTGGAGGAAGAATGCATCTGGTTTGTCCAATGAGTAAGTCTCCATATGTGGATCCTCAT
  AAATCAGGACATGAAATCTGGGAAGAATTTTCGATGAGCTTCACTCCAGCAGTGAAAGAA
  GTGGTGGAATTTGCAAAGCGTATTCCTGGGTTCAGAGATCTCTCTCAGCATGACCAGGTC
  AACCTTTTAAAGGCTGGGACTTTTGAGGTTTTAATGGTACGGTTCGCATCATTATTTGAT
  GCAAAGGAACGTACTGTCACCTTTTTAAGTGGAAAGAAATATAGTGTGGATGATTTACAC
  TCAATGGGAGCAGGGGATCTGCTAAACTCTATGTTTGAATTTAGTGAGAAGCTAAATGCC
  CTCCAACTTAGTGATGAAGAGATGAGTTTGTTTACAGCTGTTGTCCTGGTATCTGCAGAT
  CGATCTGGAATAGAAAACGTCAACTCTGTGGAGGCTTTGCAGGAAACTCTCATTCGTGCA
  CTAAGGACCTTAATAATGAAAAACCATCCAAATGAGGCCTCTATTTTTACAAAACTGCTT
  CTAAAGTTGCCAGATCTTCGATCTTTAAACAACATGCACTCTGAGGAGCTCTTGGCCTTT
  AAAGTTCACCCT
  
• Restriction Sites: Please inquire
• ACCN: NM_001145425
• ORF Size: 1515 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001145425.1, NP_001138897.1
• RefSeq Size: 5066
• RefSeq ORF: 1515
• Locus ID: 9975
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Gene Summary: This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
  Transcript Variant: This variant (2) contains an alternate first exon and initiates translation at a downstream start codon compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.