SOX6 (NM_001145819) Human Untagged Clone

CAT#: SC326501

SOX6 (untagged)-Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 4, mRNA

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SOX6
• Synonyms: HSSOX6; SOXD
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001145819, the custom clone sequence may differ by one or more nucleotides
  ATGAAAGGTCATGGTGAGCTTCAAGGACATGAAAGAAGAATGTCTTCCAAGCAAGCCACC
  TCTCCATTTGCCTGTGCAGCTGATGGAGAGGATGCAATGACCCAGGATTTAACCTCAAGG
  GAAAAGGAAGAGGGCAGTGATCAACATGTGGCCTCCCATCTGCCTCTGCACCCCATAATG
  CACAACAAACCTCACTCTGAGGAGCTACCAACACTTGTCAGTACCATTCAACAAGATGCT
  GACTGGGACAGCGTTCTGTCATCTCAGCAAAGAATGGAATCAGAGAATAATAAGTTATGT
  TCCCTATATTCCTTCCGAAATACCTCTACCTCACCACATAAGCCTGACGAAGGGAGTCGG
  GACCGTGAGATAATGACCAGTGTTACTTTTGGAACCCCAGAGCGCCGCAAAGGGAGTCTT
  GCCGATGTGGTGGACACACTGAAACAGAAGAAGCTTGAGGAAATGACTCGGACTGAACAA
  GAGGATTCCTCCTGCATGGAAAAACTACTTTCAAAAGATTGGAAGGAAAAAATGGAAAGA
  CTAAATACCAGTGAACTTCTTGGAGAAATTAAAGGTACACCTGAGAGCCTGGCAGAAAAA
  GAACGGCAGCTCTCCACCATGATTACCCAGCTGATCAGTTTACGGGAGCAGCTACTGGCA
  GCGCATGATGAACAGAAAAAACTGGCAGCGTCACAAATTGAGAAACAACGGCAGCAAATG
  GACCTTGCTCGCCAACAGCAAGAACAGATTGCGAGACAACAGCAGCAACTTCTGCAACAG
  CAGCACAAAATTAATCTCCTGCAGCAACAGATCCAGGTTCAGGGTCACATGCCTCCGCTC
  ATGATCCCAATTTTTCCACATGACCAGCGGACTCTGGCAGCAGCTGCTGCTGCCCAACAG
  GGATTCCTCTTCCCCCCTGGAATAACATACAAACCAGGTGATAACTACCCCGTACAGTTC
  ATTCCATCAACAATGGCAGCTGCTGCTGCTTCTGGACTCAGCCCTTTACAGCTCCAGAAG
  GGTCATGTCTCCCACCCACAAATTAACCAAAGGCTAAAGGGCCTAAGTGACCGTTTTGGC
  AGGAATTTGGACACCTTTGAACATGGTGGTGGCCACTCTTACAACCACAAACAGATTGAG
  CAGCTCTATGCCGCTCAGCTGGCCAGCATGCAGGTGTCACCTGGAGCAAAGATGCCATCA
  ACTCCACAGCCACCAAACACAGCAGGGACGGTCTCACCTACTGGGATAAAAAATGAAAAG
  AGAGGGACCAGCCCTGTAACTCAAGTTAAGGATGAAGCAGCAGCACAGCCTCTGAATCTC
  TCATCCCGACCCAAGACAGCAGAGCCTGTAAAGTCCCCAACGTCTCCCACCCAGAACCTC
  TTCCCAGCCAGCAAAACCAGCCCTGTCAATCTGCCAAACAAAAGCAGCATCCCTAGCCCC
  ATTGGAGGAAGCCTGGGAAGAGGATCCTCTTTAGATATCCTATCTAGTCTCAACTCCCCT
  GCCCTTTTTGGGGATCAGGATACAGTGATGAAAGCCATTCAGGAGGCGCGGAAGATGCGA
  GAGCAGATCCAGCGGGAGCAACAGCAGCAACAGCCACATGGTGTTGACGGGAAACTGTCC
  TCCATAAATAATATGGGGCTGAACAGCTGCAGGAATGAAAAGGAAAGAACGCGCTTTGAG
  AATTTGGGGCCCCAGTTAACGGGAAAGTCAAATGAAGATGGAAAACTGGGCCCAGGTGTC
  ATCGACCTTACTCGGCCAGAAGATGCAGAGGGAAGTAAAGCAATGAATGGCTCTGCAGCT
  AAACTACAGCAGTATTATTGTTGGCCAACAGGAGGTGCCACTGTGGCTGAAGCACGAGTC
  TACAGGGACGCCCGCGGCCGTGCCAGCAGCGAGCCACACATTAAGCGACCAATGAATGCA
  TTCATGGTTTGGGCAAAGGATGAGAGGAGAAAAATCCTTCAGGCCTTCCCCGACATGCAT
  AACTCCAACATTAGCAAAATCTTAGGATCTCGCTGGAAATCAATGTCCAACCAGGAGAAG
  CAACCTTATTATGAAGAGCAGGCCCGGCTAAGCAAGATCCACTTAGAGAAGTACCCAAAC
  TATAAATACAAACCCCGACCGAAACGCACCTGCATTGTTGATGGCAAAAAGCTTCGGATT
  GGGGAGTATAAGCAACTGATGAGGTCTCGGAGACAGGAGATGAGGCAGTTCTTTACTGTG
  GGGCAACAGCCTCAGATTCCAATCACCACAGGAACAGGTGTTGTGTATCCTGGTGCTATC
  ACTATGGCAACTACCACACCATCGCCTCAGATGACATCTGACTGCTCTAGCACCTCGGCC
  AGCCCGGAGCCCAGCCTCCCGGTCATCCAGAGCACTTATGGTATGAAGACAGATGGCGGA
  AGCCTAGCTGGAAATGAAATGATCAATGGAGAGGATGAAATGGAAATGTATGATGACTAT
  GAAGATGACCCCAAATCAGACTATAGCAGTGAAAATGAAGCCCCGGAGGCTGTCAGTGCC
  AAC
  
• Restriction Sites: Please inquire
• ACCN: NM_001145819
• ORF Size: 2526 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001145819.1, NP_001139291.1
• RefSeq Size: 8919
• RefSeq ORF: 2526
• Locus ID: 55553
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (4) differs in the 5' UTR and coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (a) has a distinct N-terminus and is longer than isoform b. Variants 4 and 6 both encode the same isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.