KRT72 (NM_001146226) Human Untagged Clone

CAT#: SC327024

KRT72 (untagged)-Human keratin 72 (KRT72) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KRT72
• Synonyms: K6irs; K6IRS2; KRT6; KRT6IRS2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001146226, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCCGCCAACTGACCCATTTCCCCCGCGGGGAGCGCCTGGGCTTCAGCGGTTGCTCCGCGGTCCTCT
  CTGGCGGGATCGGCAGCAGCTCCGCCTCATTCCGGGCCCGGGTCAAGGGCTCGGCCTCCTTTGGCAGCAA
  GAGCCTCTCCTGCCTTGGGGGCAGCCGAAGCCTGGCGCTCAGCGCTGCTGCACGGCGGGGCGGCGGCCGC
  CTGGGCGGCTTCGTGGGCACCGCCTTCGGCAGCGCCGGGCTGGGGCCCAAGTGTCCCTCCGTGTGCCCAC
  CCGGGGGCATCCCTCAGGTCACCGTCAACAAGAGCCTCCTGGCCCCGCTCAACGTGGAGATGGACCCCGA
  GATCCAGAGGGTGCGCGCCCAGGAGCGGGAGCAGATCAAGGCGCTAAACAACAAGTTCGCCTCCTTCATC
  GACAAGGTGCGGTTCCTGGAGCAGCAGAATCAGGTGCTAGAGACCAAGTGGAACCTCCTACAGCAGCTGG
  ACTTGAACAACTGCAGGAAGAACCTGGAGCCCATTTATGAGGGCTACATCAGCAACCTGCAGAAGCAGCT
  GGAGATGCTGTCTGGGGACGGGGTGAGGCTGGATTCGGAGCTGAGGAACATGCAGGATTTGGTGGAGGAC
  TACAAGAAGAGGTATGAGGTGGAGATTAACAGACGCACAGCTGCTGAGAATGAGTTTGTGGTGCTCAAGA
  AGGACGTGGATGCTGCTTACATGAATAAGGTTGAGCTCCAGGCCAAGGTGGACTCCTTGACAGATGAGAT
  TAAATTCTTCAAGTGCCTTTATGAAGGGGAGATCACTCAGATCCAGTCCCACATCAGCGACACGTCCATC
  GTCCTGTCAATGGACAACAACCGGGATCTGGACCTGGACAGCATCATTGCCGAGGTCCGTGCCCAGTACG
  AGGAGATTGCCCTAAAGAGCAAGGCCGAGGCTGAGACCCTGTACCAGACCAAGTGTGCCGATCTGGAGAC
  GGCCATCGCCGACGCTGAACAGCGGGGGGACTGCGCCCTGAAAGATGCCCGGGCCAAGCTGGATGAGCTG
  GAGGGCGCCCTGCACCAGGCCAAGGAGGAGCTGGCACGGATGCTGCGTGAGTACCAGGAGCTCGTGAGCC
  TGAAGCTGGCCCTGGATATGGAGATCGCCACCTACCGCAAGCTGCTGGAGAGCGAGGAGTGCAGGATGTC
  TGGCGAATATCCAAATTCTGTGAGCATCTCCGTCATCAGCAGCACCAATGCTGGGGCAGGAGGGGCTGGC
  TTCAGCATGGGCTTTGGCGCCTCAAGCAGTTATAGCTACAAAACTGCAGCTGCAGACGTCAAGACCAAAG
  GCAGCTGTGGCAGTGAGCTCAAGGATCCCCTTGCCAAAACCTCGGGGAGCAGCTGTGCCACCAAAAAGGC
  CTCCAGATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001146226
• ORF Size: 1410 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001146226.1, NP_001139698.1
• RefSeq Size: 1904
• RefSeq ORF: 1410
• Locus ID: 140807
• Gene Summary: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
  Transcript Variant: This variant (3) lacks an internal in-frame coding exon compared to variant 1, resulting in a shorter isoform (2) missing a 42 aa protein segment compared to isoform 1.