TULP3 (NM_001160408) Human Untagged Clone

CAT#: SC327050

TULP3 (untagged)-Human tubby like protein 3 (TULP3) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TULP3
• Synonyms: TUBL3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001160408, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGCTTCGCGCTGCCGGCTCAGTCCCAGCGGCGACAGTGTCTTCCATGAAGAAATGATGAAGATGC
  GACAGGCTAAGCTGGATTATCAGAGGCTACTACTTGAGAAGAGGCAAAGGAAAAAGCGCCTTGAGCCATT
  TATGGTGCAGCCCAATCCAGAAGCCAGGCTACGTCGGGCAAAGCCAAGGGCCAGTGATGAGCAGACTCCC
  TTGGTGAACTGTCATACTCCCCACAGCAATGTCATCTTACATGGTATTGATGGTCCAGCTGCTGTCCTGA
  AACCAGACGAAGTTCATGCTCCATCAGTAAGCTCCTCTGTTGTGGAAGAAGATGCTGAAAACACCGTGGA
  TACTGCTTCCAAGCCAGGACTTCAGGAGCGTCTCCAAAAGCATGATATCTCTGAAAGTGTGAACTTCGAT
  GAGGAGACTGATGGAATATCCCAGTCAGCATGTTTAGAAAGACCCAATTCTGCATCAAGCCAGAATTCAA
  CCGATACAGGCACTTCCGGTTCTGCTACTGCCGCCCAACCAGCTGATAACCTCCTGGGAGACATAGACGA
  CCTGGAGGACTTTGTGTATAGTCCTGCCCCTCAAGGTGTCACAGTAAGATGTCGGATAATCCGGGATAAA
  AGGGGAATGGATCGGGGTCTCTTCCCCACCTACTATATGTACTTGGAAAAAGAAGAAAATCAGAAGATAT
  TTCTTCTTGCAGCTAGAAAGCGGAAAAAGAGCAAAACAGCCAACTACCTTATCTCCATTGATCCAGTTGA
  TTTATCTCGTGAAGGAGAAAGTTATGTCGGCAAGCTTAGATCCAACCTCATGGGGACCAAGTTTACAGTT
  TATGACCGTGGCATCTGCCCCATGAAGGGCCGGGGTTTGGTAGGAGCGGCCCACACCCGGCAGGAGCTGG
  CTGCCATCTCCTATGAAACAAACGTACTTGGATTTAAAGGTCCTAGGAAAATGTCTGTGATCATTCCTGG
  AATGACACTGAATCATAAGCAGATCCCCTATCAGCCACAAAACAACCATGACAGTTTGCTCTCAAGGTGG
  CAGAACAGAACTATGGAAAATCTGGTTGAGCTGCACAACAAGGCCCCCGTCTGGAACAGTGACACTCAGT
  CCTATGTCCTCAACTTCCGTGGCCGGGTCACTCAGGCGTCTGTGAAGAACTTCCAGATAGTCCACAAAAA
  TGACCCTGATTATATAGTCATGCAGTTTGGACGTGTGGCAGATGACGTGTTCACACTGGATTACAACTAC
  CCACTTTGTGCAGTACAGGCCTTTGGCATCGGTCTTTCTAGCTTTGACAAATGTATCCAAACCTTGAGAA
  TGCAGGAGCTCTGTGAGCTCCACCGTCAGCACCATTCAGCTGCATCCCTTGTGCACAGAACTGTTTGCCA
  GCGTTGGGTGGGACACCCGTGGCGGCTGCTCCCTCAGACCTCCCTTCTGTGGACTGACCTCTCACCTCCG
  CCTGTTGTTCCTGCACCACATCAGATAAGCATGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001160408
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001160408.1, NP_001153880.1
• RefSeq Size: 2001 bp
• RefSeq ORF: 1506 bp
• Locus ID: 7289
• Cytogenetics: 12p13.33
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009]'
  Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a longer and distinct C-terminus compared to isoform 1.