SARS2 (NM_001145901) Human Untagged Clone

CAT#: SC327060

SARS2 (untagged)-Human seryl-tRNA synthetase 2 mitochondrial (SARS2) nuclear gene encoding mitochondrial protein transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SARS2
• Synonyms: mtSerRS; SARS; SARSM; SerRS; SerRSmt; SERS; SYS
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001145901, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTGCGTCCATGGCGCGGCGCTTGTGGCCTTTGCTGACTCGTCGGGGGTTCCGGCCCCGGGGAGGCT
  GCATCTCCAACGATAGTCCAAGGAGAAGTTTCACTACAGAGAAACGAAACCGGAACCTCCTGTACGAGTA
  TGCGCGCGAGGGCTACAGCGCACTCCCTCAGCTGGACATAGAGCGGTTCTGCGCATGCCCAGAAGAGGCC
  GCACACGCCCTGGAGCTCCGCAAGGGGGAGCTGCGCTCGGCGGACCTGCCCGCGATCATCTCGACATGGC
  AGGAGCTGAGGCAGCTGCAGGAGCAGATCCGGAGCCTGGAGGAAGAGAAGGCAGCTGTGACTGAGGCAGT
  GCGGGCCCTGCTGGCAAACCAGGACAGTGGTGAAGTGCAGCAGGTGCGGCTGGATCCAGGTGCTGGCTCC
  ATATTTGGTCCTACGTTCCTCCCATTCCCAGGCCAGCTTTCTCTCCTTGTGGAGGCCCAGCTTGAGGAGC
  AGTTCTACCTGCAGGCGCTGAAGCTGCCCAACCAGACCCACCCAGACGTGCCCGTCGGGGATGAGAGCCA
  GGCTCGAGTGCTCCACATGGTCGGAGACAAGCCAGTTTTCTCCTTCCAACCTCGGGGCCACCTGGAAATT
  GGCGAGAAACTCGACATCATCCGTCAGAAGCGCCTGTCCCACGTGTCTGGCCACCGGTCCTATTACCTGC
  GCGGGGCTGGAGCCCTCCTGCAGCACGGCCTGGTCAACTTCACATTCAACAAGCTTCTCCGCCGGGGCTT
  CACCCCCATGACGGTGCCAGACCTTCTCCGCGGAGCAGTGTTTGAAGGCTGTGGGATGACACCAAATGCC
  AACCCATCCCAAATTTACAACATCGACCCTGCCCGCTTCAAAGATCTCAACCTGGCTGGAACAGCGGAGG
  TGGGGCTTGCAGGCTACTTCATGGACCACACCGTGGCCTTCAGGGACCTGCCAGTCAGGATGGTTTGCTC
  CAGCACCTGCTACCGGGCAGAGACAAACACGGGACAGGAACCCCGGGGGCTGTATCGAGTACACCACTTC
  ACCAAGGTGGAGATGTTTGGGGTGACAGGCCCTGGGCTGGAGCAGAGCTCACAGCTGCTGGAGGAGTTCC
  TGTCCCTTCAGATGGAGATCTTGACAGAGCTGGGCTTGCACTTCCGGGTCCTGGATATGCCCACCCAAGA
  ACTGGGCCTCCCCGCCTACCGCAAGTTTGACATTGAGGCCTGGATGCCAGGCCGAGGCCGCTTTGGAGAG
  GTCACCAGTGCTTCCAACTGCACAGACTTCCAGAGCCGCCGCCTCCACATCATGTTCCAGACCGAGGCTG
  GGGAGCTGCAGTTTGCCCACACGGTGAACGCCACCGCCTGTGCTGTCCCCCGCCTTCTCATCGCGCTCCT
  GGAGAGTAACCAGCAGAAGGACGGCTCAGTGCTCGTGCCCCCTGCCCTCCAGTCCTACCTCGGCACTGAT
  CGGATCACAGCCCCTACCCACGTGCCTCTCCAGTACATCGGCCCCAACCAGCCCCGGAAGCCTGGGCTGC
  CTGGCCAGCCTGCTGTAAGCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001145901
• ORF Size: 1563 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001145901.1, NP_001139373.1
• RefSeq Size: 2083
• RefSeq ORF: 1563
• Locus ID: 54938
• Protein Pathways: Aminoacyl-tRNA biosynthesis
• Gene Summary: This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).