Acinus (ACIN1) (NM_001164816) Human Untagged Clone

CAT#: SC327137

ACIN1 (untagged)-Human apoptotic chromatin condensation inducer 1 (ACIN1) transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACIN1
• Synonyms: ACINUS; ACN; fSAP152
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001164816, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCTCCGGCTGATCGCTGCCGCTCCGCCAATACAATAGAGCCAGCCACTACCAGCAGCCTGGCCCTCT
  TCCTCCTTCTCCAGAGAGACCAATCCAGCCGAACTCGGGGTTTGCCTGAGGAGAAGGAGGAAGTGACCAT
  GGACACAAGTGAAAACAGACCTGAAAATGATGTTCCAGAACCTCCCATGCCTATTGCAGACCAAGTCAGC
  AATGATGACCGCCCGGAGGGCAGTGTTGAAGATGAGGAGAAGAAAGAGAGCTCGCTGCCCAAATCATTCA
  AGAGGAAGATCTCCGTTGTCTCAGCTACCAAGGGGGTGCCAGCTGGAAACAGTGACACAGAGGGGGGCCA
  GCCTGGTCGGAAACGACGCTGGGGAGCCAGCACAGCCACCACACAGAAGAAACCTTCCATCAGTATCACC
  ACTGAATCACTAAAGAGCCTCATCCCCGACATCAAACCCCTGGCGGGGCAGGAGGCTGTTGTGGATCTTC
  ATGCTGATGACTCTCGCATCTCTGAGGATGAGACAGAGCGTAATGGCGATGATGGGACCCATGACAAGGG
  GCTGAAAATATGCCGGACAGTCACTCAGGTAGTACCTGCAGAGGGCCAGGAGAATGGGCAGAGGGAAGAA
  GAGGAAGAAGAGAAGGAACCTGAAGCAGAACCTCCTGTACCTCCCCAGGTGTCAGTAGAGGTGGCCTTGC
  CCCCACCTGCAGAGCATGAAGTAAAGAAAGTGACTTTAGGAGATACCTTAACTCGACGTTCCATTAGCCA
  GCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTGCCCTCCCCACCCCGG
  GGCAAGATTAGCAACATTGTCCATATCTCCAATTTGGTCCGTCCTTTCACTTTAGGCCAGCTAAAGGAGT
  TGTTGGGGCGCACAGGAACCTTGGTGGAAGAGGCCTTCTGGATTGACAAGATCAAATCTCATTGCTTTGT
  AACGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCTGCACGGGGTCAAATGGCCCCAGTCC
  AATCCCAAATTCCTTTGTGCTGACTATGCCGAGCAAGATGAGCTGGATTATCACCGAGGCCTCTTGGTGG
  ACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCACCCCCACCCCC
  GGTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGGGCAGTGCGGGAACAGTGGGCA
  GAACGGGAACGGGAAATGGAGCGGCGGGAGCGGACTCGATCAGAGCGTGAATGGGATCGGGACAAAGTTC
  GAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGCCGCCGCAAGGAACGTGCGAAGTCTAAAGAAAA
  GAAGAGTGAGAAGAAAGAGAAAGCCCAGGAGGAACCACCTGCCAAGCTGCTGGATGACCTTTTCCGAAAG
  ACCAAGGCAGCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGATCGTTCAGAAAGAGGCAGAGC
  GGGCCGAACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAAAAGGAGCGGGA
  GAAGGAAGCCGAGCGGGAACGGAACCGACAGCTGGAGCGAGAGAAACGTCGGGAGCACAGTCGGGAGAGG
  GACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAGATCGGGATAGGGAAAGGGACCGAG
  AACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACACCTGT
  GCGGGACCGGGGTGGGCGCCGCTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001164816
• ORF Size: 1845 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001164816.1, NP_001158288.1
• RefSeq Size: 2467
• RefSeq ORF: 1845
• Locus ID: 22985
• Protein Pathways: Spliceosome
• Gene Summary: Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
  Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (4), also known as ACINUS-S', has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.