Lactoperoxidase (LPO) (NM_001160102) Human Untagged Clone

CAT#: SC327144

LPO (untagged)-Human lactoperoxidase (LPO) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LPO
• Synonyms: SPO
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001160102, the custom clone sequence may differ by one or more nucleotides
  ATGAGGGTCCTTCTCCATCTCCCAGCCCTCCTGGCTTCCCTCATCTTGCTTCAGGCTGCA
  GCATCTACCACAAGAGATCCCAGCCTGGACTTGACTTCACTGTCTCTGGAGGTGGGCTGT
  GGTGCTCCTGCTCCCGTGGTGAGATGCGACCCGTGCAGCCCTTACCGCACCATTACGGGA
  GACTGCAATAACAGGAGGAAGCCTGCGCTGGGCGCCGCCAACAGGGCTCTGGCGCGCTGG
  CTGCCCGCGGAGTACGAGGACGGGCTCTCCCTGCCCTTCGGCTGGACGCCGGGGAAGACG
  CGCAACGGCTTCCCTCTCCCGCTGGCCCGGGAGGTATCTAACAAGATTGTTGGCTATCTG
  AATGAGGAGGGTGTTCTGGACCAAAACAGGTCCCTGCTCTTCATGCAGTGGGGTCAGATT
  GTGGATCATGACCTGGACTTTGCCCCTGACACCGAGCTGGGGAGTAGCGAGTACTCCAAA
  GCCCAGTGTGATGAGTACTGTATCCAGGGAGACAACTGCTTCCCCATCATGTTCCCACCC
  AATGACCCCAAGGCGGGGACTCAAGGGAAATGCATGCCTTTCTTCCGAGCTGGGTTCGTC
  TGCCCCACTCCACCCTACAAGTCCCTGGCCCGAGAGCAGATCAACGCTCTGACCTCCTTC
  CTGGATGCCAGCTTTGTGTACAGCTCCGAGCCAAGCCTGGCCAGCCGCCTCCGCAACCTC
  AGCAGCCCCCTGGGCCTCATGGCTGTCAACCAGGAGGTCTCAGACCATGGACTACCCTAC
  CTGCCCTATGACAGCAAGAAGCCAAGCCCCTGTGAGTTCATCAACACCACTGCCCGTGTG
  CCCTGCTTCCTGGCAGGAGATTCTCGAGCCTCAGAGCATATTCTGCTGGCCACATCCCAC
  ACCCTCTTTCTCCGCGAGCATAACCGGCTGGCCAGAGAACTAAAGAGACTCAACCCTCAG
  TGGGATGGAGAGAAGCTCTACCAGGAAGCCCGGAAAATCCTGGGAGCCTTCGTGCAGATT
  ATCACCTTTAGGGACTACCTACCCATTTTGCTAGGTGACCACATGCAGAAGTGGATACCC
  CCATATCAAGGCTACAGTGAATCTGTGGATCCCAGAATTTCCAATGTCTTCACCTTCGCC
  TTCCGCTTTGGCCACTTGGAGGTCCCCTCTAGTATGTTCCGCCTGGATGAGAATTATCAG
  CCATGGGGGCCAGAACCAGAACTCCCCCTCCACACCCTCTTCTTCAACACTTGGAGGATG
  GTCAAAGATGGTGGAATTGATCCTCTGGTGCGGGGCCTGCTGGCCAAGAAATCCAAGCTG
  ATGAAACAGAATAAAATGATGACTGGAGAGCTGCGCAACAAGCTTTTCCAGCCAACTCAC
  AGGATCCATGGCTTTGACCTGGCTGCCATCAACACACAGCGTTGCCGGGACCATGGGCAA
  CCTGGGTACAATTCCTGGAGAGCCTTCTGTGACCTCTCACAGCCGCAGACACTAGAGGAG
  TTGAACACAGTGCTGAAGAGCAAGATGCTGGCCAAGAAGTTACTGGGTCTCTACGGGACC
  CCTGACAACATCGACATCTGGATAGGGGCCATTGCTGAGCCGCTGGTGGAAAGGGGTCGG
  GTGGGGCCTCTCCTGGCCTGCCTCTTGGGCAAGCAGTTCCAGCAGATCCGTGATGGAGAC
  AGGTTCTGGTGGGAAAACCCTGGGGTCTTCACGAACGAGCAGAAGGACTCTCTACAGAAA
  ATGTCCTTCTCACGCCTTGTCTGTGACAACACCCGCATCACCAAGGTCCCACGGGACCCA
  TTCTGGGCCAACAGCTACCCCTATGACTTCGTGGATTGCTCAGCCATCGACAAGCTGGAC
  CTGTCACCCTGGGCCTCAGTGAAGAAT
  
• Restriction Sites: Please inquire
• ACCN: NM_001160102
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001160102.1, NP_001153574.1
• RefSeq Size: 2744 bp
• RefSeq ORF: 1890 bp
• Locus ID: 4025
• Cytogenetics: 17q22
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: 'This gene encodes a member of the peroxidase family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Following its secretion from salivary, mammary, and other mucosal glands, this enzyme catalyzes the generation of the antimicrobial substance hypothiocyanous acid. This gene is present in a gene cluster on chromosome 17. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]'
  Transcript Variant: This variant (3) lacks two alternate exons in the 5' coding region, compared to variant 1. The resulting isoform (3) lacks an internal segment near the N-terminus, compared to isoform 1. This isoform is thought to be secreted but the sites of proteolytic processing have not been determined.