Acinus (ACIN1) (NM_001164815) Human Untagged Clone

CAT#: SC327305

ACIN1 (untagged)-Human apoptotic chromatin condensation inducer 1 (ACIN1) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACIN1
• Synonyms: ACINUS; ACN; fSAP152
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001164815, the custom clone sequence may differ by one or more nucleotides
  ATGTGGAGACGGAAACATCCGAGGACATCCGGAGGAACCCGGGGAGTTCTGAGTGGTAAT
  CGAGGGGTAGAGTATGGCAGTGGGCGGGGTCATCTCGGTACGTTCGAAGGGCGTTGGCGG
  AAATTACCGAAGATGCCCGAAGCCGTCGGGACGGACCCGAGTACCTCACGCAAGATGGCG
  GAGCTGGAGGAGGTGACTCTGGACGGGAAGCCTCTTCAGGCGCTGCGGGTGACCGACCTG
  AAGGCCGCACTGGAGCAGCGAGGCCTAGCCAAGAGCGGGCAGAAGAGTGCCCTGGTCAAG
  CGGCTCAAAGGGGCTCTAATGCTAGAAAATTTACAGAAACACTCAACACCCCATGCTGCA
  TTCCAGCCAAATTCCCAGATTGGTGAGGAAATGAGCCAGAACAGTTTCATAAAACAGTAT
  CTGGAAAAGCAGCAGGAGCTACTTAGGCAGCGTCTGGAACGTGAAGCTCGAGAAGCTGCA
  GAACTTGAAGGAAAAAGCTCCTCAATTTCTGAAGAGAAAGGTGACTCTGATGATGAGAAA
  CCAAGGAAAGGAGAAAGACGATCATCTAGGGTCAGACAGGCAAGAGCAGCTAAACTGTCT
  GAGGGCAGCCAACCTGCTGAGGAGGAAGAGGATCAAGAAACACCTTCCAGAAACCTAAGG
  GTCAGAGCAGATCGAAATTTGAAAACAGAGGAGGAAGAAGAGGAGGAGGAGGAGGAGGAA
  GAAGATGATGAAGAAGAGGAAGGTGATGATGAGGGACAAAAATCTAGGGAGGCACCAATC
  CTGAAAGAGTTTAAGGAAGAAGGGGAAGAGATACCTAGAGTAAAACCAGAGGAGATGATG
  GATGAGAGACCCAAAACAAGATCCCAGGAACAGGAGGTGTTAGAGAGAGGAGGGAGATTT
  ACAAGATCCCAGGAAGAGGCTAGAAAAAGTCATCTGGCCAGACAGCAGCAGGAGAAGGAA
  ATGAAAACAACATCTCCCCTTGAGGAGGAAGAAAGAGAAATAAAATCTTCACAAGGCTTA
  AAGGAAAAATCGAAGTCTCCTTCCCCTCCTCGACTGACTGAAGATCGAAAGAAGGCCTCA
  CTTGTAGCGCTGCCAGAGCAAACTGCCAGCGAGGAGGAGACTCCTCCACCTTTACTAACA
  AAGGAAGCATCTTCTCCACCACCTCATCCACAGCTCCATAGCGAAGAAGAAATAGAGCCC
  ATGGAAGGCCCAGCCCCCCCTGTCCTCATTCAGTTATCTCCTCCTAATACAGATGCTGAC
  ACCAGGGAGCTATTAGTATCTCAGCATACTGTCCAGTTGGTAGGAGGCCTGTCTCCTTTG
  TCAAGTCCTTCAGACACCAAAGCAGAATCTCCAGCAGAGAAAGTGCCAGAGGAGAGTGTC
  CTGCCTCTGGTTCAGAAAAGCACACTGGCTGACTACTCAGCCCAGAAGGATCTTGAACCT
  GAGTCAGACAGATCTGCTCAGCCCCTCCCTCTAAAAATTGAGGAATTAGCACTGGCCAAA
  GGAATCACTGAAGAATGTCTGAAACAGCCATCTTTGGAACAGAAGGAAGGCAGAAGAGCT
  TCTCATACCCTTCTCCCAAGCCACAGATTGAAACAGTCAGCTGATTCATCCTCTAGCCGG
  TCCTCCTCATCTTCCTCCTCCAGTTCTAGATCAAGATCTCGCTCTCCTGACAGTTCAGGT
  TCTCGGTCTCATTCACCGCTCAGATCCAAGCAGAGAGATGTAGCCCAGGCACGTACTCAT
  GCCAACCCTCGTGGTAGACCCAAGATGGGCTCCAGATCAACATCAGAGTCCAGATCAAGG
  TCACGTTCACGTTCTCGTTCAGCATCAAGCAACAGCAGAAAATCTCTGAGCCCTGGAGTC
  TCCAGGGACAGCAGCACCAGCTATACTGAAACCAAAGATCCCTCTTCTGGTCAGGAGGTT
  GCAACTCCACCAGTGCCACAACTGCAGGTCTGTGAGCCAAAGGAGAGGACTTCCACCTCC
  TCATCCTCTGTCCAAGCAAGGCGTCTGAGTCAGCCTGAATCAGCTGAAAAGCATGTGACC
  CAGAGGTTACAGCCTGAGCGGGGGAGCCCAAAGAAGTGTGAAGCTGAAGAGGCAGAGCCA
  CCAGCTGCCACACAGCCCCAAACCTCAGAGACTCAGACCTCTCATCTGCCAGAATCAGAA
  AGAATTCATCACACTGTTGAGGAGAAGGAGGAAGTGACCATGGACACAAGTGAAAACAGA
  CCTGAAAATGATGTTCCAGAACCTCCCATGCCTATTGCAGACCAAGTCAGCAATGATGAC
  CGCCCGGAGGGCAGTGTTGAAGATGAGGAGAAGAAAGAGAGCTCGCTGCCCAAATCATTC
  AAGAGGAAGATCTCCGTTGTCTCAGCTACCAAGGGGGTGCCAGCTGGAAACAGTGACACA
  GAGGGGGGCCAGCCTGGTCGGAAACGACGCTGGGGAGCCAGCACAGCCACCACACAGAAG
  AAACCTTCCATCAGTATCACCACTGAATCACTAAAGAGCCTCATCCCCGACATCAAACCC
  CTGGCGGGGCAGGAGGCTGTTGTGGATCTTCATGCTGATGACTCTCGCATCTCTGAGGAT
  GAGACAGAGCGTAATGGCGATGATGGGACCCATGACAAGGGGCTGAAAATATGCCGGACA
  GTCACTCAGGTAGTACCTGCAGAGGGCCAGGAGAATGGGCAGAGGGAAGAAGAGGAAGAA
  GAGAAGGAACCTGAAGCAGAACCTCCTGTACCTCCCCAGGTGTCAGTAGAGGTGGCCTTG
  CCCCCACCTGCAGAGCATGAAGTAAAGAAAGTGACTTTAGGAGATACCTTAACTCGACGT
  TCCATTAGCCAGCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCC
  CAGGTGCCCTCCCCACCCCGGGGCAAGATTAGCAACATTGTCCATATCTCCAATTTGGTC
  CGTCCTTTCACTTTAGGCCAGCTAAAGGAGTTGTTGGGGCGCACAGGAACCTTGGTGGAA
  GAGGCCTTCTGGATTGACAAGATCAAATCTCATTGCTTTGTAACGTACTCAACAGTAGAG
  GAAGCTGTTGCCACCCGCACAGCTCTGCACGGGGTCAAATGGCCCCAGTCCAATCCCAAA
  TTCCTTTGTGCTGACTATGCCGAGCAAGATGAGCTGGATTATCACCGAGGCCTCTTGGTG
  GACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCA
  CCCCCACCCCCGGTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGG
  GCAGTGCGGGAACAGTGGGCAGAACGGGAACGGGAAATGGAGCGGCGGGAGCGGACTCGA
  TCAGAGCGTGAATGGGATCGGGACAAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCC
  CGTGACCGCCGCCGCAAGGAACGTGCGAAGTCTAAAGAAAAGAAGAGTGAGAAGAAAGAG
  AAAGCCCAGGAGGAACCACCTGCCAAGCTGCTGGATGACCTTTTCCGAAAGACCAAGGCA
  GCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGATCGTTCAGAAAGAGGCAGAG
  CGGGCCGAACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAA
  AAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACCGACAGCTGGAGCGAGAGAAACGT
  CGGGAGCACAGTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGG
  GACCGAGATCGGGATAGGGAAAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGAC
  ACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACACCTGTGCGGGACCGGGGTGGGCGC
  CGC
  
• Restriction Sites: Please inquire
• ACCN: NM_001164815
• ORF Size: 3906 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001164815.1, NP_001158287.1
• RefSeq Size: 4828
• RefSeq ORF: 3906
• Locus ID: 22985
• Protein Pathways: Spliceosome
• Gene Summary: Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
  Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.