STAU2 (NM_001164384) Human Untagged Clone

CAT#: SC327560

STAU2 (untagged)-Human staufen RNA binding protein homolog 2 (Drosophila) (STAU2) transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STAU2
• Synonyms: 39K2; 39K3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001164384, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTTCAAATAAATCAGATGTTCTCAGTGCAGCTGAGTCTTGGTGAGCAGACATGGGAATCCGAAGGCA
  GCAGTATAAAGAAGGCTCAGCAGGCTGTTGCCAATAAAGCTTTGACTGAATCTACGCTTCCCAAACCAGT
  TCAGAAGCCACCCAAAAGTAATGTTAACAATAACCCAGGCAGTATAACTCCAACTGTGGAACTGAATGGG
  CTTGCTATGAAAAGGGGAGAGCCTGCCATCTACAGGCCATTAGATCCAAAGCCATTCCCAAATTATAGAG
  CTAATTACAACTTTCGGGGCATGTACAATCAGAGGTATCATTGCCCAGTGCCTAAGATCTTTTATGTTCA
  GCTCACTGTAGGAAATAATGAATTTTTTGGGGAAGGAAAGACTCGACAAGCTGCTAGACACAATGCTGCA
  ATGAAAGCCCTCCAAGCACTGCAGAATGAACCTATTCCAGAAAGATCTCCTCAGAATGGTGAATCAGGAA
  AGGATGTGGATGATGACAAAGATGCAAATAAGTCTGAGATCAGCTTAGTGTTTGAAATTGCTCTGAAGCG
  AAATATGCCTGTCAGTTTTGAGGTTATTAAAGAAAGTGGACCACCACATATGAAAAGCTTTGTTACTCGA
  GTGTCAGTAGGAGAGTTCTCTGCAGAAGGAGAAGGAAATAGCAAAAAACTCTCCAAGAAGCGCGCTGCGA
  CCACCGTCTTACAGGAGCTTAAAAAACTTCCACCTCTTCCTGTGGTGGAAAAGCCAAAACTATTTTTTAA
  AAAACGCCCTAAAACAATAGTAAAGGCCGGACCAGAATATGGCCAAGGGATGAACCCTATTAGCCGCCTG
  GCGCAAATTCAACAGGCCAAAAAGGAAAAGGAGCCGGATTATGTTTTGCTTTCAGAAAGAGGAATGCCTC
  GACGTCGAGAATTTGTGATGCAGGTGAAGGTAGGCAATGAAGTTGCTACAGGAACAGGACCTAATAAAAA
  GATAGCCAAAAAAAATGCTGCAGAAGCAATGCTGTTACAACTTGGTTATAAAGCATCCACTAATCTTCAG
  GATCAACTTGAGAAGACAGGGGAAAACAAAGGATGGAGTGGTCCAAAGCCTGGGTTTCCTGAACCAACAA
  ATAATACTCCAAAAGGAATTCTTCATTTGTCTCCTGATGTTTATCAAGAGATGGAAGCCAGCCGCCACAA
  AGTAATCTCTGGCACTACTCTAGGCTATTTGTCACCCAAAGATATGAACCAACCTTCAAGCTCTTTCTTC
  AGTATATCTCCCACATCGAATAGTTCAGCTACAATTGCCAGGGAACTCCTTATGAATGGAACATCTTCTA
  CAGCTGAAGCCATAGGTTTAAAAGGAAGTTCTCCTACTCCCCCTTGTTCTCCAGTACAACCTTCAAAACA
  ACTGGAATATTTAGCAAGGATTCAAGGCTTTCAGGTATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001164384
• ORF Size: 1440 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001164384.1, NP_001157856.1
• RefSeq Size: 4225
• RefSeq ORF: 1440
• Locus ID: 27067
• Protein Families: Transcription Factors
• Gene Summary: Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
  Transcript Variant: This variant (6) differs in the 5' and 3' UTRs and coding sequence compared to variant 1. The resulting isoform (e) has shorter and distinct N- and C-termini compared to isoform a. Variants 5 and 6 both encode the same isoform (e).