EME1 (NM_001166131) Human Untagged Clone

CAT#: SC327602

EME1 (untagged)-Human essential meiotic endonuclease 1 homolog 1 (S. pombe) (EME1) transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EME1
• Synonyms: MMS4L; SLX2A
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001166131, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTCTAAAGAAGTCATCACCCTCACTGGATTCTGGTGATAGTGACTCTGAGGAGTTGCCAACATTTG
  CCTTTCTGAAGAAGGAACCATCTTCAACAAAGAGGAGACAGCCTGAAAGGGAAGAGAAGATTGTAGTGGT
  TGACATCTCAGATTGTGAAGCCTCCTGTCCTCCAGCACCAGAGTTATTTTCACCACCTGTCCCAGAAATA
  GCTGAAACTGTCACACAAACACAGCCAGTCAGGTTGCTAAGCAGTGAAAGTGAAGATGAAGAAGAATTTA
  TTCCTCTGGCTCAAAGGCTTACATGTAAGTTTCTGACCCACAAGCAACTGAGCCCTGAGGACTCTAGCTC
  CCCAGTTAAAAGTGTTTTGGATCATCAAAATAATGAAGGTGCATCATGTGACTGGAAAAAGCCCTTTCCA
  AAGATCCCTGAAGTTCCCCTCCATGATACCCCAGAGAGGAGTGCAGCAGATAACAAGGACCTGATCTTAG
  ATCCATGCTGTCAGCTTCCAGCCTACCTGTCTACCTGCCCTGGCCAGAGCAGCAGCTTGGCAGTAACCAA
  AACAAATTCTGACATCCTTCCACCCCAGAAGAAAACCAAGCCGAGTCAGAAGGTCCAGGGAAGAGGCTCA
  CACGGATGCCGGCAGCAGAGACAAGCAAGGCAGAAGGAAAGCACCCTGAGAAGACAGGAAAGAAAGAATG
  CAGCACTGGTTACCAGGATGAAAGCCCAGAGGCCAGAGGAATGCTTAAAACACATCATTGTAGTGCTGGA
  TCCAGTGCTCTTACAGATGGAAGGTGGGGGCCAGCTCCTAGGAGCACTGCAGACCATGGAGTGCCGCTGT
  GTGATTGAGGCGCAGGCTGTGCCTTGCAGTGTCACTTGGAGGAGAAGGGCTGGGCCGTCTGAGGACAGAG
  AGGACTGGGTGGAGGAGCCAACAGTACTGGTGTTGCTCCGGGCAGAGGCATTTGTGTCCATGATCGACAA
  TGGAAAGCAGGGAAGCCTGGACAGCACTATGAAAGGGAAGGAAACGCTTCAGGGCTTTGTAACTGACATC
  ACAGCAAAGACAGCAGGGAAAGCTCTGTCACTGGTGATTGTGGATCAGGAGAAATGCTTCAGCCTGGAGC
  TGCTGTTCTTTGATTTCCTCCCCTGCACCAGTGCTCAGAATCCTCCAAGAAGAGGGAAACAGGGAGCAAA
  TAAACAGACCAAGAAGCAGCAGCAGAGACAACCAGAGGCCAGCATAGGGTCCATGGTATCCAGGGTAGAC
  GCTGAAGAGGCATTGGTGGATCTGCAGCTACACACAGAAGCCCAGGCTCAAATTGTGCAGAGCTGGAAAG
  AGCTGGCCGACTTCACATGCGCATTCACAAAGGCTGTGGCTGAGGCGCCCTTCAAGAAGCTCCGAGATGA
  AACTACCTTCTCCTTCTGTCTGGAGAGTGACTGGGCTGGAGGGGTGAAGGTGGACCTTGCTGGCAGGGGA
  CTCGCACTAGTCTGGAGGAGACAGATTCAGCAGCTGAACCGAGTCAGCCTGGAAATGGCCAGTGCAGTTG
  TGAATGCCTATCCCTCCCCACAGCTCCTGGTACAGGCTTATCAGCAGTGTTTTTCGGATAAAGAACGCCA
  GAATTTGCTCGCAGACATACAGGTGCGCCGTGGGGAAGGTGTGACATCCACTTCTCGCCGCATTGGACCA
  GAACTATCCAGGCGTATCTACCTTCAGATGACCACTTTACAGCCACATCTCTCTTTAGATAGTGCTGACT
  GA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001166131
• ORF Size: 1752 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001166131.1, NP_001159603.1
• RefSeq Size: 2371
• RefSeq ORF: 1752
• Locus ID: 146956
• Protein Pathways: Homologous recombination
• Gene Summary: This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).