POLR3B (NM_001160708) Human Untagged Clone

CAT#: SC327695

POLR3B (untagged)-Human polymerase (RNA) III (DNA directed) polypeptide B (POLR3B) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POLR3B
• Synonyms: C128; HLD8; INMAP; RPC2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001160708, the custom clone sequence may differ by one or more nucleotides
  ATGAAAGCCAATGAAAAGGTTACAAGTGACGCTGACCCTATGTGGTACTTAAAATATCTT
  AATATCTATGTTGGGCTTCCTGATGTTGAAGAAAGCTTCAATGTAACTAGACCAGTGTCC
  CCTCATGAGTGCCGTTTGAGAGACATGACATACTCTGCCCCTATTACAGTGGATATTGAA
  TATACCCGAGGCAGCCAGAGGATCATCCGCAATGCCTTACCTATCGGCAGAATGCCCATA
  ATGCTACGTAGTTCAAACTGTGTTCTTACAGGAAAAACGCCAGCAGAATTTGCCAAACTG
  AACGAATGTCCCTTAGATCCAGGTGGCTACTTCATTGTTAAAGGAGTAGAAAAAGTTATT
  CTTATCCAAGAGCAGCTGTCTAAGAACAGGATCATCGTGGAGGCTGATAGAAAAGGGGCT
  GTTGGAGCTTCAGTTACCAGCTCTACCCATGAGAAAAAAAGCAGAACCAATATGGCTGTG
  AAACAAGGACGATTTTATTTGAGGCATAATACTTTGTCAGAAGATATACCCATTGTCATC
  ATATTTAAGGCCATGGGTGTTGAGAGTGACCAGGAAATTGTGCAGATGATTGGAACAGAG
  GAGCACGTGATGGCTGCATTTGGGCCCAGTCTGGAAGAGTGCCAGAAAGCTCAGATTTTC
  ACACAGATGCAGGCATTAAAATATATAGGGAACAAAGTAAGAAGGCAAAGGATGTGGGGA
  GGTGGACCAAAGAAAACCAAAATAGAAGAAGCAAGAGAGCTCCTGGCTTCCACCATTCTG
  ACCCATGTCCCAGTTAAGGAATTCAATTTCCGAGCCAAATGTATCTATACTGCAGTGATG
  GTGCGAAGAGTTATTCTGGCCCAAGGAGATAATAAAGTTGACGACAGAGATTATTATGGT
  AACAAGCGACTGGAATTGGCAGGACAGCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAA
  AAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCC
  CAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCT
  ATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAA
  GTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAG
  TTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATG
  CTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTT
  ATGACACACATCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTG
  GGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTT
  GTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACA
  TTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTT
  ACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATT
  GTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTAC
  AGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAA
  AATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAG
  ATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAAC
  CAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGA
  TACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCC
  ATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAAT
  GCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAAC
  AAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACG
  TTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCT
  ACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGT
  GAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATT
  CCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTAC
  AAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCT
  TTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGC
  AGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTT
  TGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATG
  ACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTC
  CACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGC
  CATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTA
  GAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGAT
  AAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGA
  CGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTAT
  GGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGAT
  GTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCC
  TGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAG
  TCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAATGAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001160708
• ORF Size: 3228 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001160708.1, NP_001154180.1
• RefSeq Size: 4133
• RefSeq ORF: 3228
• Locus ID: 55703
• Protein Families: Transcription Factors
• Protein Pathways: Cytosolic DNA-sensing pathway, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase
• Gene Summary: This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (2) differs in the 5' UTR and initiates translation at an in-frame downstream AUG, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.