KIF7 (NM_198525) Human Untagged Clone

CAT#: SC328068

KIF7 (untagged)-Human kinesin family member 7 (KIF7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KIF7
• Synonyms: ACLS; AGBK; HLS2; JBTS12; UNQ340
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_198525, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGCTGGAGGCTCAGAGGCTGCCAGGGGCTGAGGAGGCCCCAGTGCGGGTTGCCCTGCGAGTTCGAC
  CACTGCTGCCCAAGGAGCTGCTGCACGGGCATCAGAGCTGCCTGCAGGTGGAGCCAGGGCTTGGCCGCGT
  CACTCTGGGCCGTGACCGACACTTTGGCTTCCACGTGGTGCTGGCCGAGGATGCGGGGCAGGAGGCCGTG
  TACCAGGCCTGCGTTCAGCCCCTCCTTGAGGCCTTCTTCGAGGGCTTCAATGCCACTGTCTTTGCCTATG
  GTCAGACGGGCTCAGGGAAGACATACACCATGGGGGAGGCCAGTGTGGCCTCCCTCCTTGAGGATGAGCA
  GGGCATTGTCCCGAGGGCCATGGCCGAGGCCTTCAAGCTCATCGATGAGAACGACCTGCTTGACTGTCTG
  GTACATGTGTCCTACCTGGAAGTGTACAAGGAGGAGTTCCGAGACCTGCTCGAGGTGGGCACTGCCAGCC
  GTGACATCCAGCTCCGGGAAGATGAGCGCGGGAATGTTGTGCTGTGCGGGGTGAAGGAGGTCGACGTGGA
  GGGCCTGGATGAGGTGCTGAGCCTCCTGGAGATGGGCAACGCGGCGCGGCACACGGGAGCCACGCACCTC
  AACCACCTGTCTAGCCGCTCACACACGGTCTTCACCGTGACCCTGGAGCAGCGGGGGCGCGCCCCCAGCC
  GCCTACCCCGCCCCGCCCCGGGCCAGCTGCTCGTCTCCAAGTTCCACTTCGTGGACCTGGCGGGCTCAGA
  GAGGGTGCTCAAGACGGGCAGCACCGGCGAGCGGCTCAAGGAGAGCATCCAGATCAACAGCAGCCTCCTG
  GCGCTGGGCAACGTCATCAGCGCCCTGGGGGACCCTCAGCGCCGGGGCAGCCACATACCCTACCGCGACT
  CCAAGATCACCCGGATCCTCAAAGACTCGCTGGGCGGGAACGCCAAGACGGTGATGATCGCCTGCGTCAG
  CCCTTCCTCCTCCGACTTCGACGAGACCCTCAACACCCTCAACTACGCCAGCCGCGCCCAGAACATCCGC
  AACCGCGCCACGGTCAACTGGCGGCCCGAGGCCGAGCGGCCACCCGAAGAGACGGCGAGCGGCGCGCGGG
  GTCCGCCACGGCACCGCTCCGAGACCCGCATCATCCACCGCGGCCGGCGCGCCCCAGGCCCAGCCACCGC
  CTCCGCGGCGGCCGCCATGCGCCTGGGCGCCGAGTGCGCGCGCTACCGGGCCTGCACCGACGCCGCCTAC
  AGCCTCTTGCGCGAGCTGCAGGCCGAGCCCGGGCTGCCCGGCGCCGCCGCCCGCAAGGTGCGCGACTGGC
  TGTGCGCCGTCGAGGGCGAGCGCAGCGCCCTGAGCTCCGCCTCCGGGCCCGATAGCGGCATCGAGAGCGC
  CTCCGTCGAGGACCAGGCGGCGCAGGGGGCCGGCGGGCGAAAGGAGGATGAGGGGGCGCAGCAGCTGCTG
  ACCCTGCAGAACCAGGTGGCGCGGCTGGAGGAGGAGAACCGAGACTTTCTGGCTGCGCTGGAGGACGCCA
  TGGAGCAGTACAAACTGCAGAGCGACCGGCTGCGTGAGCAGCAGGAGGAGATGGTGGAACTGCGGCTGCG
  GTTAGAGCTGGTGCGGCCAGGCTGGGGGGGCCCGCGGCTCCTGAATGGCCTGCCTCCCGGGTCCTTTGTG
  CCTCGACCTCATACAGCCCCCCTGGGGGGTGCCCACGCCCATGTGCTGGGCATGGTGCCGCCTGCCTGCC
  TCCCTGGAGATGAAGTTGGCTCTGAGCAGAGGGGAGAGCAGGTGACAAATGGCAGGGAGGCTGGAGCTGA
  GTTGCTGACTGAGGTGAACAGGCTGGGAAGTGGCTCTTCAGCTGCTTCAGAGGAGGAAGAGGAGGAGGAG
  GAGCCGCCCAGGCGGACCTTACACCTGCGCAGAAATAGGATCAGCAACTGCAGTCAGAGGGCGGGGGCAC
  GCCCAGGGAGTCTGCCAGAGAGGAAGGGCCCAGAGCTTTGCCTTGAGGAGTTGGATGCAGCCATTCCAGG
  GTCCAGAGCAGTTGGTGGGAGCAAGGCCCGAGTTCAGGCCCGCCAGGTCCCCCCTGCCACAGCCTCAGAG
  TGGCGGCTGGCCCAGGCCCAGCAGAAGATCCGGGAGCTGGCTATCAACATCCGCATGAAGGAGGAGCTTA
  TTGGCGAGCTGGTCCGCACAGGAAAGGCAGCTCAGGCCCTGAACCGCCAGCACAGCCAGCGTATCCGGGA
  GCTGGAGCAGGAGGCAGAGCAGGTGCGGGCCGAGCTGAGTGAAGGCCAGAGGCAGCTGCGGGAGCTCGAG
  GGCAAGGAGCTCCAGGATGCTGGCGAGCGGTCTCGGCTCCAGGAGTTCCGCAGGAGGGTCGCTGCGGCCC
  AGAGCCAGGTGCAGGTGCTGAAGGAGAAGAAGCAGGCTACGGAGCGGCTGGTGTCACTGTCGGCCCAGAG
  TGAGAAGCGACTGCAGGAGCTCGAGCGGAACGTGCAGCTCATGCGGCAGCAGCAGGGACAGCTGCAGAGG
  CGGCTTCGCGAGGAGACGGAGCAGAAGCGGCGCCTGGAGGCAGAAATGAGCAAGCGGCAGCACCGCGTCA
  AGGAGCTGGAGCTGAAGCATGAGCAACAGCAGAAGATCCTGAAGATTAAGACGGAAGAGATCGCGGCATT
  CCAGAGGAAGAGGCGCAGTGGCAGCAACGGCTCTGTGGTCAGCCTGGAACAGCAGCAGAAGATTGAGGAG
  CAGAAGAAGTGGCTGGACCAGGAGATGGAGAAGGTGCTACAGCAGCGGCGGGCGCTGGAGGAGCTGGGGG
  AGGAGCTCCACAAGCGGGAGGCCATCCTGGCCAAGAAGGAGGCCCTGATGCAGGAGAAGACGGGGCTGGA
  GAGCAAGCGCCTGAGATCCAGCCAGGCCCTCAACGAGGACATCGTGCGAGTGTCCAGCCGGCTGGAGCAC
  CTGGAGAAGGAGCTGTCCGAGAAGAGCGGGCAGCTGCGGCAGGGCAGCGCCCAGAGCCAGCAGCAGATCC
  GCGGGGAGATCGACAGCCTGCGCCAGGAGAAGGACTCGCTGCTCAAGCAGCGCCTGGAGATCGACGGCAA
  GCTGAGGCAGGGGAGTCTGCTGTCCCCCGAGGAGGAGCGGACGCTGTTCCAGTTGGATGAGGCCATCGAG
  GCCCTGGATGCTGCCATTGAGTATAAGAATGAGGCCATCACATGCCGCCAGCGGGTGCTTCGGGCCTCAG
  CCTCGTTGCTGTCCCAGTGCGAGATGAACCTCATGGCCAAGCTCAGCTACCTCTCATCCTCAGAGACCAG
  AGCCCTCCTCTGCAAGTATTTTGACAAGGTGGTGACGCTCCGAGAGGAGCAGCACCAGCAGCAGATTGCC
  TTCTCGGAACTGGAGATGCAGCTGGAGGAGCAGCAGAGGCTGGTGTACTGGCTGGAGGTGGCCCTGGAGC
  GGCAGCGCCTGGAGATGGACCGCCAGCTGACCCTGCAGCAGAAGGAGCACGAGCAGAACATGCAGCTGCT
  CCTGCAGCAGAGTCGAGACCACCTCGGTGAAGGGTTAGCAGACAGCAGGAGGCAGTATGAGGCCCGGATT
  CAAGCTCTGGAGAAGGAACTGGGCCGTTACATGTGGATAAACCAGGAACTGAAACAGAAGCTCGGCGGTG
  TGAACGCTGTAGGCCACAGCAGGGGTGGGGAGAAGAGGAGCCTGTGCTCGGAGGGCAGACAGGCTCCTGG
  AAATGAAGATGAGCTCCACCTGGCACCCGAGCTTCTCTGGCTGTCCCCCCTCACTGAGGGGGCCCCCCGC
  ACCCGGGAGGAGACGCGGGACTTGGTCCACGCTCCGTTACCCTTGACCTGGAAACGCTCGAGCCTGTGTG
  GTGAGGAGCAGGGGTCCCCCGAGGAACTGAGGCAGCGGGAGGCGGCTGAGCCCCTGGTGGGGCGGGTGCT
  TCCTGTGGGTGAGGCAGGCCTGCCCTGGAACTTTGGGCCTTTGTCCAAGCCCCGGCGGGAACTGCGACGA
  GCCAGCCCGGGGATGATTGATGTCCGGAAAAACCCCCTGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_198525
• ORF Size: 4032 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_198525.2, NP_940927.2
• RefSeq Size: 4575
• RefSeq ORF: 4032
• Locus ID: 374654
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011]