ZFYVE27 (NM_001174119) Human Untagged Clone

CAT#: SC328594

ZFYVE27 (untagged)-Human zinc finger FYVE domain containing 27 (ZFYVE27) transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZFYVE27
• Synonyms: PROTRUDIN; SPG33
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001174119, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAGACATCAGAACGTGAGGGGAGTGGGCCGGAGCTGAGCCCCAGCGTGATGCCCGAGGCTCCCCTGG
  AGTCTCCACCTTTTCCTACCAAGTCCCCAGCGTTTGACCTTTTCAACTTGGTTCTCTCCTACAAGAGGCT
  GGAGATCTACCTGGAACCCTTGAAGGATGCAGGTGCATGGTACTCAGTAGGTGCCCTGATGATTTCAGTG
  CCCGCCCTGCTGGGCTACCTTCAGGAGGTTTGCCGGGCACGGCTGCCTGATTCCGAGCTGATGCGGAGGA
  AGTATCATAGCGTGAGGCAGGAGGACCTGCAGAGAGGTCGCCTGTCTCGTCCCGAGGCCGTGGCTGAGGT
  GAAGAGCTTCTTGATCCAGCTGGAGGCCTTCCTGAGCCGCCTGTGCTGCACATGTGAAGCCGCCTACCGC
  GTGCTGCACTGGGAGAACCCCGTCGTGTCCTCACAGTTCTATGGGGCTCTTCTGGGCACAGTCTGCATGC
  TGTATTTGCTGCCACTCTGCTGGGTTCTCACCCTTTTAAACAGCACGCTCTTTCTGGGGAATGTGGAGTT
  CTTCCGAGTTGTGTCTGAGTACAGGGCATCTCTGCAGCAGAGGATGAACCCAAAGCAGGAAGAGCATGCC
  TTTGAGAGTCCTCCACCACCAGATGTTGGGGGGAAGGATGGTCTGATGGACAGCACGCCTGCCCTCACAC
  CCACGGAGGACCTCACACCGGGCAGCGTGGAGGAGGCTGAGGAGGCTGAGCCAGATGAAGAGTTTAAAGA
  TGCGATTGAGGAGGATGATGAGGGCGCCCCGTGCCCAGCAGAGGATGAGCTGGCCCTGCAGGACAACGGG
  TTCCTGAGCAAGAATGAGGTGCTGCGCAGCAAGGTGTCTCGGCTCACGGAGCGGCTCCGCAAGCGCTACC
  CCACCAACAACTTCGGGAACTGCACGGGCTGCTCGGCCACCTTCTCAGTGCTGAAGAAGAGGCGGAGCTG
  CAGTAATTGTGGAAACAGCTTCTGCTCTCGATGCTGCTCCTTCAAGGTGCCCAAGTCCTCCATGGGGGCC
  ACAGCCCCTGAAGCCCAGAGGGAGACTGTGTTTGTGTGTGCCTCGTGTAACCAGACCTTGAGCAAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001174119
• ORF Size: 1119 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001174119.1, NP_001167590.1
• RefSeq Size: 2938
• RefSeq ORF: 1119
• Locus ID: 118813
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (4) differs in the 5' UTR, uses two alternate in-frame splice sites, and lacks two in-frame alternate exons compared to variant 1. This results in a shorter protein (isoform d), compared to isoform a.