C2CD6 (NM_001168216) Human Untagged Clone

CAT#: SC328629

ALS2CR11 (untagged)-Human amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 11 (ALS2CR11) transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: C2CD6
• Synonyms: ALS2CR11
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001168216, the custom clone sequence may differ by one or more nucleotides
  ATGGAGCCACCCCAAGAGACAAATAGGCCTTTCAGCACACTTGATAACCGCAGCGGGCAG
  GTCCAAGTCCTGTCCGCCACCCCGCTATTGCAGAGGAATCCCTACAGCAGCCCGGATATC
  ATGCACATTAAAGGGTCGGAGGCTTCTTCGGTCCCTTACGCCCTGAACCAGGGCACGACG
  GCCCTGCCTAAGAACAAGAACCAGGAGGGCACCGGGCACCGGCTGCTGAACATGCTGAGA
  AAAACTCTTAAAGAGTCTGATAGTGAAGAACTGGAAATAACACAGGAGACACCAAATTTG
  GTGCCATTTGGGGATGTGGTTGGCTGCCTGGGCATTCATATAAAGAACTGCAGACATTTT
  ATGCCTAAGATCAGTTTACAACATTATGCTAATTTATTCATTCGCATCTCTATAAACAAA
  GCTGTGAAATGTACAAAAATGTGTAGCTTGCTATCCAAAAACGATGAGAAGAACACTGTA
  ATTAAGTTCGATGAAGTGAAGTATTTTTCTGTACAGGTTCCCAGACGTTATGATGATAAG
  CGGAATAATATTTTATTGGAACTCATACAATATGACAATAGAGAAAAACGTGCTTTCTTG
  TTAGGGAGTGTTCAGATACATCTTTATGAGGTAATTCAGAAAGGGTGCTTCATTGAAGAG
  GTCCAAGTGTTGCATGGAAACATATTTGTCTGCAGGCTGGAGGTGGAATTTATGTTCTCC
  TATGGAAACTTTGGTTATGGATTTTCACATCAGTTAAAACCTCTTCAGAAAATTACTGAG
  CCATCCATGTTTATGAATCTTGCACCACCTCCAGAAAGAACAGATCCCGTGACAAAAGTT
  ATTACACCACAGACAGTAGAATATCCAGCATTCTTATCCCCAGACCTGAATGTTACTGTT
  GGGACTCCAGCTGTGCAATCCTCCAACCAGCCATCTGTAGTGCGACTTGAAAAACTTCAG
  CAACAACCCCGGGAAAGGCTGGAAAAGATGAAAAAAGAATATAGAAATCTGAATACATGG
  ATAGATAAAGCTAACTATTTAGAAAGCATTCTAATGCCAAAATTGGAACATAAGGATTCT
  GAGGAAACTAATATAGATGAGGCATCTGAAAACACGAAAAGTAATCATCCTGAAGAGGAG
  CTTGAAAATATTGTAGGAGTAGGTGGCTTTTTCACCAAAAGAATATAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001168216
• ORF Size: 1188 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001168216.1, NP_001161688.1
• RefSeq Size: 1779
• RefSeq ORF: 1188
• Locus ID: 151254
• Gene Summary: An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes this gene. The encoded protein contains a calcium-dependent membrane targeting C2 domain. This domain is often found in proteins that are involved in membrane trafficking and signal transduction. [provided by RefSeq, Jun 2016]
  Transcript Variant: This variant (4) lacks several alternate exons in the 3' coding region, compared to variant 1, one of which results in a frameshift. The resulting protein (isoform 4) has a shorter and distinct C-terminus, compared to isoform 1.