ATXN10 (NM_001167621) Human Untagged Clone

CAT#: SC328667

ATXN10 (untagged)-Human ataxin 10 (ATXN10) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ATXN10
• Synonyms: E46L; HUMEEP; SCA10
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001167621, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGG
  AGGCCCTGCGCGCGCTCACGGCGCTCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGC
  TGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGT
  GGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGCATGCTT
  TCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTT
  GTTTACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATA
  GATGCTTACCAAAAACATCCTGAATCAGAATGGCCGTTCTTGATTATTACAGACCTCTTTCTGAAAAGCC
  CGGAATTGGTACAAGCCATGTTTCCCAAACTGAACAATCAAGAAAGAGTTACACTGTTAGACCTTATGAT
  AGCCAAGATAACGAGTGATGAGCCACTCACCAAGGATGACATCCCTGTGTTTTTGCGGCATGCTGAGTTG
  ATTGCAAGCACCTTTGTGGATCAGTGCAAGACTGTGCTCAAGCTGGCCTCTGAGGAGCCTCCTGATGATG
  AGGAGGCACTGGCTACAATTAGGCTTCTCGACGTCCTGTGCGAAATGACTGTGAATACTGAGCTGCTCGG
  CTATCTGCAGGTTTTCCCTGGCTTGCTGGAAAGAGTGATTGATCTTTTGCGGGTGATTCATGTAGCTGGA
  AAAGAAACCACAAACATCTTCAGTAATTGTGGTTGCGTGAGAGCAGAAGGTGACATCTCCAATGTGGCCA
  ATGGGTTTAAGTCTCATCTCATTCGTCTGATTGGAAATCTGTGTTACAAGAATAAAGATAACCAAGACAA
  GGTAAATGAGCTGGATGGTATCCCGTTGATCCTGGACAACTGCAACATCAGTGACAGTAACCCCTTTCTG
  ACCCAGTGGGTGATATATGCCATCCGAAACCTTACCGAAGACAACAGCCAAAACCAAGATTTGATTGCAA
  AGATGGAGGAACAGGGGCTGGCAGATGCATCCCTACTTAAAAAAGTGGGTTTTGAAGTTGAAAAGAAAGG
  CGAAAAGCTGATCCTGAAATCTACTAGAGACACCCCTAAGCCATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001167621
• ORF Size: 1236 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001167621.1, NP_001161093.1
• RefSeq Size: 3148
• RefSeq ORF: 1236
• Locus ID: 25814
• Gene Summary: This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2016]
  Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.