EIF2B3 (NM_001166588) Human Untagged Clone

CAT#: SC328668

EIF2B3 (untagged)-Human eukaryotic translation initiation factor 2B subunit 3 gamma 58kDa (EIF2B3) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EIF2B3
• Synonyms: EIF-2B; EIF2Bgamma
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001166588, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAATTTCAAGCAGTAGTGATGGCAGTAGGTGGAGGATCTCGGATGACAGACCTAACTTCCAGCATTC
  CCAAACCTCTGCTTCCAGTTGGGAACAAACCTTTAATTTGGTACCCATTGAACCTGCTTGAGCGTGTTGG
  ATTTGAAGAAGTCATTGTGGTTACAACCAGGGATGTTCAAAAGGCTCTATGTGCAGAATTCAAGATGAAA
  ATGAAGCCAGATATTGTGTGTATTCCTGATGACGCTGACATGGGAACTGCAGATTCTTTGCGCTACATAT
  ATCCAAAACTTAAGACAGATGTGCTGGTGCTGAGCTGTGATCTGATAACAGACGTTGCCTTACATGAGGT
  TGTGGACCTGTTTAGAGCTTATGATGCATCACTTGCTATGTTGATGAGAAAAGGCCAAGATAGCATAGAA
  CCTGTTCCCGGTCAAAAGGGGAAAAAAAAAGCAGTGGAGCAGCGTGACTTCATTGGAGTGGACAGCACAG
  GAAAGAGGCTGCTCTTCATGGCTAATGAAGCAGACTTGGATGAAGAGCTGGTCATTAAGGGATCCATCCT
  ACAGAAGCATCCTAGAATACGTTTCCACACGGGTCTTGTGGATGCCCACCTCTACTGTTTGAAAAAATAC
  ATCGTGGATTTCCTAATGGAAAATGGGTCAATAACTTCTATCCGGAGTGAACTGATTCCATATTTAGTGA
  GAAAACAGTTTTCCTCAGCTTCCTCACAACAGGGACAAGAAGAAAAAGAGGAGGATCTAAAGAAAAAGGA
  GCTGAAGTCCTTAGATATCTACAGTTTTATAAAAGAAGCCAATACACTGAACCTGGCTCCCTATGATGCC
  TGCTGGAATGCCTGTCGAGGAGACAGGTGGGAAGACTTGTCCAGATCACAGGTGCGCTGCTATGTCCACA
  TCATGAAAGAGGGGCTCTGCTCTCGAGTGAGCACACTGGGACTCTACATGGAAGCAAACAGACAGGTGCC
  CAAATTGCTGTCTGCTCTCTGTCCAGAAGAACCACCAGTCCATTCGTCAGCCCAGATTGTCAGCAAACAC
  CTGGTTGGAGTTGACAGCCTCATTGGGCCAGAGACACAGATTGGAGAGAAGTCATCCATTAAGCGCTCAG
  TCATTGGCTCATCCTGTCTCATAAAAGATAGAGTGACTATTACCAATTGCCTTCTCATGAACTCAGTCAC
  TGTGGAGGAAGGGTATGTTTCCCCCTGTACCCACTTGAGGCAAAGATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001166588
• ORF Size: 1239 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001166588.2, NP_001160060.1
• RefSeq Size: 1607
• RefSeq ORF: 1239
• Locus ID: 8891
• Gene Summary: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (2) differs in the 3' end compared to variant 1, and encodes a shorter isoform (2) with a distinct C-terminus compared to isoform 1.