SH3KBP1 (NM_001184960) Human Untagged Clone

CAT#: SC328701

SH3KBP1 (untagged)-Human SH3-domain kinase binding protein 1 (SH3KBP1) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SH3KBP1
• Synonyms: AGMX2; CD2BP3; CIN85; GIG10; HSB-1; HSB1; IMD61; MIG18
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001184960, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGAGAAGAGACTATTGGGAAGAAGTTACCTGCAACTACAGCAACTCCAGACTCATCAAAAACAGAAA
  TGGACAGCAGGACAAAGAGCAAGGATTACTGCAAAGTAATATTTCCATATGAGGCACAGAATGATGATGA
  ATTGACAATCAAAGAAGGAGATATAGTCACTCTCATCAATAAGGACTGCATCGACGTAGGCTGGTGGGAA
  GGAGAGCTGAACGGCAGACGAGGCGTGTTCCCCGATAACTTCGTGAAGTTACTTCCACCGGACTTTGAAA
  AGGAAGGGAATAGACCCAAGAAGCCACCGCCTCCATCCGCTCCTGTCATCAAACAAGGGGCAGGCACCAC
  TGAGAGAAAACATGAAATTAAAAAGATACCTCCTGAAAGACCAGAAATGCTTCCAAACAGAACAGAAGAA
  AAAGAAAGACCAGAGAGAGAGCCAAAACTGGATTTACAGAAGCCCTCCGTTCCTGCCATACCGCCAAAAA
  AGCCTCGGCCACCTAAGACCAATTCTCTCAGCAGACCTGGCGCACTGCCCCCGAGAAGGCCGGAGAGACC
  GGTGGGTCCGCTGACACACACCAGGGGTGACAGTCCAAAGATTGACTTGGCCGGCAGTTCGCTATCTGGC
  ATCCTGGACAAAGATCTCTCGGACCGCAGCAATGACATTGACTTAGAAGGTTTTGACTCCGTGGTATCAT
  CTACTGAGAAACTCAGTCATCCGACCACAAGCAGACCAAAAGCTACAGGGAGGCGGCCTCCGTCCCAGTC
  CCTCACATCTTCATCCCTTTCAAGCCCTGATATCTTCGACTCCCCAAGTCCCGAAGAGGATAAGGAGGAA
  CACATTTCACTTGCGCACAGAGGAGTGGACGCGTCAAAGAAAACTTCCAAGACTGTTACCATATCCCAAG
  TGTCTGACAACAAAGCATCCCTGCCGCCCAAGCCGGGGACCATGGCAGCAGGTGGCGGTGGGCCAGCCCC
  TCTGTCCTCAGCGGCGCCCTCCCCCCTGTCATCCTCTTTGGGAACAGCTGGACACAGAGCCAACTCCCCG
  TCTCTGTTCGGCACGGAAGGAAAACCAAAGATGGAGCCTGCGGCCAGCAGCCAGGCGGCCGTGGAGGAGC
  TAAGGACACAGGTCCGCGAGCTGAGGAGCATCATCGAGACCATGAAGGACCAGCAGAAACGAGAGATTAA
  ACAGTTATTGTCTGAGTTGGATGAAGAGAAGAAAATCCGGCTTCGGTTGCAGATGGAAGTGAACGACATA
  AAGAAAGCTCTACAATCAAAATGA
  
  
• Restriction Sites: SgfI-NotI
• ACCN: NM_001184960
• ORF Size: 1284 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001184960.1, NP_001171889.1
• RefSeq Size: 3864
• RefSeq ORF: 1284
• Locus ID: 30011
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis
• Gene Summary: This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
  Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (c) has a distinct N-terminus and is shorter than isofor