TRMT2B (NM_001167971) Human Untagged Clone

CAT#: SC328758

TRMT2B (untagged)-Human TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae) (TRMT2B) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRMT2B
• Synonyms: CXorf34; dJ341D10.3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001167971, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGGCCTTAAGAGAAGAGTCCCACTGCACAGCCTCAGATACTTCATCTCCATGGTGGGTCTCTTCT
  CCAAACCAGGACTGCTTCCCTGGTATGCCAGAAATCCACCAGGATGGTCACAGCTCTTTCTGGGCACAGT
  ATGTAAGGGAGATTTCACCCGTGTGATAGCCACGAAATGTCAGAAAGGACAAAAAAGTCAGAAGAAACCA
  AGCCATCTTGGACCACTAGATGGTTCCTGGCAGGAAAGGCTGGCTGATGTTGTGACACCACTCTGGAGGT
  TGAGCTATGAAGAACAGCTCAAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGTGAACCG
  AGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGT
  GTGCAGTCTAATCATCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCC
  TTCGACAGTCTCCATTGGAGCCCTGCCTTGTATTTCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCG
  CACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATTAAGTCAGGAGGAGCTC
  CATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCAC
  TTTACTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGA
  ACCCTACATCTTTGAAGAACTTCTGAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAAC
  ACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGACTGGAGTGAACTCTGACACCATCCTTC
  TTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCTTGGGAT
  TGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAA
  TTTCATACTGGTCAAGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTG
  TTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCATTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGC
  CATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAATGTCATTGAGCTGTGC
  TGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATT
  TGTTCCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001167971
• ORF Size: 1380 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001167971.1, NP_001161443.1
• RefSeq Size: 3162
• RefSeq ORF: 1380
• Locus ID: 79979
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]
  Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame exon in the coding region, compared to variant 1. It encodes isoform b, which is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.