NOSTRIN (NM_001171632) Human Untagged Clone

CAT#: SC328781

NOSTRIN (untagged)-Human nitric oxide synthase trafficker (NOSTRIN) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOSTRIN
• Synonyms: DaIP2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001171632, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGGACCCACTGACAGATTGTCCGTATAATAAAGTATACAAGAACCTAAAGGAGTTTTCTCAAAATG
  GAGAGAATTTCTGCAAACAGGTCACATCTGTTCTTCAGCAAAGTTGTGTTAGCAGTGCCTGGGCCTGGGC
  CTCAGAGGGAATGAAATCCACAGCGGACCTGCATCAAAAACTTGGCAAAGCAATTGAATTGGAAGCAATA
  AAACCGACTTATCAAGTCCTAAATGTACAAGAGAAGAAGAGAAAATCACTTGACAATGAAGTTGAAAAGA
  CAGCAAATCTTGTCATTAGCAACTGGAATCAGCAAATTAAGGCCAAGAAGAAATTAATGGTTAGTACCAA
  GAAACATGAAGCACTTTTCCAGCTTGTAGAAAGCTCCAAGCAATCTATGACTGAGAAGGAGAAGCGGAAG
  CTCCTCAATAAACTGACAAAATCAACTGAAAAGTTGGAAAAGGAAGATGAAAATTACTACCAAAAAAACA
  TGGCGGGTTATTCTACCAGACTGAAATGGGAAAACACACTAGAGAACTGCTACCAGAGCATTCTGGAGCT
  GGAGAAGGAAAGAATTCAACTTTTATGCAATAACTTAAACCAGTACAGCCAACATATTTCTCTTTTTGGC
  CAAACCCTGACCACATGCCACACGCAGATTCACTGTGCCATCAGCAAGATTGACATTGAAAAAGATATCC
  AGGCTGTAATGGAAGAAACTGCAATTTTATCTACAGAAAACAAATCTGAGTTCCTGTTAACGGATTACTT
  TGAAGAAGATCCTAACAGTGCAATGGATAAAGAGAGACGAAAGTCTTTACTAAAACCAAAATTATTGAGA
  CTGCAGAGAGACATTGAAAAAGCCTCAAAAGACAAGGAAGGCCTGGAACGAATGCTTAAAACGTACTCCA
  GCACCTCCTCCTTCTCTGATGCAAAGAGCCAGAAAGACACAGCAGCGTTAATGGATGAGAACAATTTGAA
  ACTAGACCTTTTGGAAGCGAACTCCTACAAACTGTCATCAATGTTAGCAGAACTTGAGCAAAGACCTCAA
  CCCAGCCATCCTTGTAGTAATTCCATCTTCAGGTGGAGGGAAAAGGAGCATACTCATAGCTATGTGAAAA
  TATCTCGGCCTTTTTTAATGAAGAGATTAGAGAATATTGTGAGCAAGGCATCTTCTGGTGGGCAGAGCAA
  TCCAGGTTCTTCAACTCCAGCCCCTGGTGCAGCCCAGCTCAGCAGCAGACTTTGCAAGGCCTTGTATTCT
  TTTCAAGCCAGGCAAGATGATGAGTTGAATTTGGAAAAGGGTGACATTGTGATTATACACGAGAAAAAAG
  AAGGAGGATGGTGGTTTGGATCTTTGAATGGGAAAAAAGGCCATTTTCCTGCCGCTTATGTGGAGGAGTT
  ACCTTCAAATGCTGGCAACACAGCTACAAAGGCATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001171632
• ORF Size: 1437 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001171632.1, NP_001165103.1
• RefSeq Size: 1863
• RefSeq ORF: 1437
• Locus ID: 115677
• Gene Summary: Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production. [supplied by OMIM, Apr 2004]
  Transcript Variant: This variant (3) lacks an exon in the 5' CDS, as compared to variant 2. The resulting isoform (3) lacks an internal segment, as compared to isoform 2.