YTHDF2 (NM_001172828) Human Untagged Clone

CAT#: SC328872

YTHDF2 (untagged)-Human YTH domain family member 2 (YTHDF2) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: YTHDF2
• Synonyms: CAHL; HGRG8; NY-REN-2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001172828, the custom clone sequence may differ by one or more nucleotides
  ATGTCAGATTCCTACTTACCCAGTTACTACAGTCCCTCCATTGGCTTCTCCTATTCTTTG
  GGTGAAGCTGCTTGGTCTACGGGGGGTGACACAGCCATGCCCTACTTAACTTCTTATGGA
  CAGCTGAGCAACGGAGAGCCCCACTTCCTACCAGATGCAATGTTTGGGCAACCAGGAGCC
  CTAGGTAGCACTCCATTTCTTGGTCAGCATGGTTTTAATTTCTTTCCCAGTGGGATTGAC
  TTCTCAGCATGGGGAAATAACAGTTCTCAGGGACAGTCTACTCAGAGCTCTGGATATAGT
  AGCAATTATGCTTATGCACCTAGCTCCTTAGGTGGAGCCATGATTGATGGACAGTCAGCT
  TTTGCCAATGAGACCCTCAATAAGGCTCCTGGCATGAATACTATAGACCAAGGGATGGCA
  GCACTGAAGTTGGGTAGCACAGAAGTTGCAAGCAATGTTCCAAAAGTTGTAGGTTCTGCT
  GTTGGTAGCGGGTCCATTACTAGTAACATCGTGGCTTCCAATAGTTTGCCTCCAGCCACC
  ATTGCTCCTCCAAAACCAGCATCTTGGGCTGATATTGCTAGCAAGCCTGCAAAACAGCAA
  CCTAAACTGAAGACCAAGAATGGCATTGCAGGGTCAAGTCTTCCGCCACCCCCGATAAAG
  CATAACATGGATATTGGAACTTGGGATAACAAGGGTCCCGTTGCAAAAGCCCCCTCACAG
  GCTTTGGTTCAGAATATAGGTCAGCCAACCCAGGGGTCTCCTCAGCCTGTAGGTCAGCAG
  GCTAACAATAGCCCACCAGTGGCTCAGGCATCAGTAGGGCAACAGACACAGCCATTGCCT
  CCACCTCCACCACAGCCTGCCCAGCTTTCAGTCCAGCAACAGGCAGCTCAGCCAACCCGC
  TGGGTAGCACCTCGGAACCGTGGCAGTGGGTTCGGTCATAATGGGGTGGATGGTAATGGA
  GTAGGACAGTCTCAGGCTGGTTCTGGATCTACTCCTTCAGAACCCCACCCAGTGTTGGAG
  AAGCTTCGGTCCATTAATAACTATAACCCCAAAGATTTTGACTGGAATCTGAAACATGGC
  CGGGTTTTCATCATTAAGAGCTACTCTGAGGACGATATTCACCGTTCCATTAAGTATAAT
  ATTTGGTGCAGCACAGAGCATGGTAACAAGAGACTGGATGCTGCTTATCGTTCCATGAAC
  GGGAAAGGCCCCGTTTACTTACTTTTCAGTGTCAACGGCAGTGGACACTTCTGTGGCGTG
  GCAGAAATGAAATCTGCTGTGGACTACAACACATGTGCAGGTGTGTGGTCCCAGGACAAA
  TGGAAGGGTCGTTTTGATGTCAGGTGGATTTTTGTGAAGGACGTTCCCAATAGCCAACTG
  CGACACATTCGCCTAGAGAACAACGAGAATAAACCAGTGACCAACTCTAGGGACACTCAG
  GAAGTGCCTCTGGAAAAGGCTAAGCAGGTGTTGAAAATTATAGCCAGCTACAAGCACACC
  ACTTCCATTTTTGATGACTTCTCACACTATGAGAAACGCCAAGAGGAAGAAGAAAGTGTT
  AAAAAGGAACGTCAAGGTCGTGGGAAATAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001172828
• ORF Size: 1590 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001172828.1, NP_001166299.1
• RefSeq Size: 2723
• RefSeq ORF: 1590
• Locus ID: 51441
• Gene Summary: This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]
  Transcript Variant: This variant (3) lacks an exon in the 5' region, which results in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, as compared to isoform 1.