SP110 (NM_001185015) Human Untagged Clone

CAT#: SC328902

SP110 (untagged)-Human SP110 nuclear body protein (SP110) transcript variant d

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SP110
• Synonyms: IFI41; IFI75; IPR1; VODI
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001185015, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGAGGGGCTTCAGGATGTTCACCATGACAAGAGCCATGGAAGAGGCTCTTTTTCAGCACTTCATGC
  ACCAGAAGCTGGGGATCGCCTATGCCATACACAAGCCATTTCCCTTCTTTGAAGGCCTCCTAGACAACTC
  CATCATCACTAAGAGAATGTACATGGAATCTCTGGAAGCCTGTAGAAATTTGATCCCTGTATCCAGAGTG
  GTGCACAACATTCTCACCCAACTGGAGAGGACTTTTAACCTGTCTCTTCTGGTGACATTGTTCAGTCAAA
  TTAACCTGCGTGAATATCCCAATCTGGTGACGATTTACAGAAGCTTCAAACGTGTTGGTGCTTCCTATGA
  ATGGCAGAGCAGAGACACACCAATCCTACTTGAAGCCCCAACTGGCCTAGCAGAAGGAAGCTCCCTCCAT
  ACCCCACTGGCGCTGCCCCCACCACAACCCCCTCAACCAAGCTGTTCACCCTGTGCGCCAAGAGTCAGTG
  AGCCTGGAACATCCTCCCAGCAAAGCGATGAGATCCTGAGTGAGTCGCCCAGCCCATCTGACCCTGTCCT
  GCCTCTCCCTGCACTCATCCAGGAAGGAAGAAGCACTTCAGTGACCAATGACAAGTTAACATCCAAAATG
  AATGCGGAAGAAGACTCAGAAGAGATGCCCAGCCTCCTCACTAGCACTGTGCAAGTGGCCAGTGACAACC
  TGATCCCCCAAATAAGAGATAAAGAAGACCCTCAAGAGATGCCCCACTCTCCCTTGGGCTCTATGCCAGA
  GATAAGAGATAATTCTCCAGAACCAAATGACCCAGAAGAGCCCCAGGAGGTGTCCAGCACACCTTCAGAC
  AAGAAAGGAAAGAAAAGAAAAAGATGTATCTGGTCAACTCCAAAAAGGAGACATAAGAAAAAAAGCCTCC
  CAGGAGGGACAGCCTCATCTAGACACGGAATCCAAAAGAAGCTCAAAAGGGTGGATCAGGTTCCTCAAAA
  GAAAGATGACTCAACTTGTAACTCCACGGTAGAGACAAGGGCCCAAAAGGCGAGAACTGAATGTGCCCGA
  AAGTCGAGATCAGAGGAGATCATTGATGGCACTTCAGAAATGAATGAAGGAAAGAGGTCCCAGAAGACGC
  CTAGTACACCACGAAGGGTCACACAAGGGGCAGCCTCACCTGGGCATGGCATCCAAGAGAAGCTCCAAGT
  GGTGGATAAGGTGACTCAAAGGAAAGACGACTCAACCTGGAACTCAGAGGTCATGATGAGGGTCCAAAAG
  GCAAGAACTAAATGTGCCCGAAAGTCCAGATTGAAAGAAAAGAAAAAGGAGAAAGATATCTGTTCAAGCT
  CAAAAAGGAGATTTCAGAAAAATATTCACCGAAGAGGAAAACCCAAAAGTGACACTGTGGATTTTCACTG
  TTCTAAGCTCCCCGTGACCTGTGGTGAGGCGAAAGGGATTTTATATAAGAAGAAAATGAAACACGGATCC
  TCAGTGAAGTGCATTCGGAATGAGGATGGAACTTGGTTAACACCAAATGAATTTGAAGTCGAAGGAAAAG
  GAAGGAACGCAAAGAACTGGAAACGGAATATACGTTGTGAAGGAATGACCCTAGGAGAGCTGCTGAAGAG
  TGGACTTTTGCTCTGTCCTCCAAGAATAAATCTCAAGAGAGAGTTAAATAGCAAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001185015
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001185015.1, NP_001171944.1
• RefSeq Size: 2137 bp
• RefSeq ORF: 1668 bp
• Locus ID: 3431
• Cytogenetics: 2q37.1
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (d) has an alternate 5' sequence, lacks multiple 3' exons and has an alternate 3' exon, compared to variant c. The resulting protein (isoform d) has a longer N-terminus and a shorter and distinct C-terminus when it is compared to isoform c.