NOSTRIN (NM_001171631) Human Untagged Clone

CAT#: SC328920

NOSTRIN (untagged)-Human nitric oxide synthase trafficker (NOSTRIN) transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOSTRIN
• Synonyms: DaIP2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001171631, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGGACCCACTGACAGATTGTCCGTATAATAAAGTATACAAGAACCTAAAGGAGTTTTCTCAAAATG
  GAGAGAATTTCTGCAAACAGGTCACATCTGTTCTTCAGCAAAGGGCAAACCTGGAAATTAGCTATGCCAA
  AGGACTTCAGAAACTGGCAAGCAAGCTGAGCAAAGCATTACAGAACACGAGAAAAAGTTGTGTTAGCAGT
  GCCTGGGCCTGGGCCTCAGAGGGAATGAAATCCACAGCGGACCTGCATCAAAAACTTGGCAAAGCAATTG
  AATTGGAAGCAATAAAACCGACTTATCAAGTCCTAAATGTACAAGAGAAGAAGAGAAAATCACTTGACAA
  TGAAGTTGAAAAGACAGCAAATCTTGTCATTAGCAACTGGAATCAGCAAATTAAGGCCAAGAAGAAATTA
  ATGGTTAGTACCAAGAAACATGAAGCACTTTTCCAGCTTGTAGAAAGCTCCAAGCAATCTATGACTGAGA
  AGGAGAAGCGGAAGCTCCTCAATAAACTGACAAAATCAACTGAAAAGTTGGAAAAGGAAGATGAAAATTA
  CTACCAAAAAAACATGGCGGGTTATTCTACCAGACTGAAATGGGAAAACACACTAGAGAACTGCTACCAG
  GTAACCCACAGCATCTGCCTATATGCCTTTTGGGTCAAAAGAGCCTGGGGAAAGTGTGTGAGTGATTTAA
  GATACCAAGACACATTCCTTCCTGGAAATCTCCCTCCACTATGGTTTGGATATGACATAGTCAAGAGGCT
  AATCATGAGACTTTGTTCAGTCTGTCTTCAGAGCATTCTGGAGCTGGAGAAGGAAAGAATTCAACTTTTA
  TGCAATAACTTAAACCAGTACAGCCAACATATTTCTCTTTTTGGCCAAACCCTGACCACATGCCACACGC
  AGATTCACTGTGCCATCAGCAAGATTGACATTGAAAAAGATATCCAGGCTGTAATGGAAGAAACTGCAAT
  TTTATCTACAGAAAACAAATCTGAGTTCCTGTTAACGGATTACTTTGAAGAAGATCCTAACAGTGCAATG
  GATAAAGAGAGACGAAAGTCTTTACTAAAACCAAAATTATTGAGACTGCAGAGAGACATTGAAAAAGCCT
  CAAAAGACAAGGAAGGCCTGGAACGAATGCTTAAAACGTACTCCAGCACCTCCTCCTTCTCTGATGCAAA
  GAGCCAGAAAGACACAGCAGCGTTAATGGATGAGAACAATTTGAAACTAGACCTTTTGGAAGCGAACTCC
  TACAAACTGTCATCAATGTTAGCAGAACTTGAGCAAAGACCTCAACCCAGCCATCCTTGTAGTAATTCCA
  TCTTCAGGTGGAGGGAAAAGGAGCATACTCATAGCTATGTGAAAATATCTCGGCCTTTTTTAATGAAGAG
  ATTAGAGAATATTGTGAGCAAGGCATCTTCTGGTGGGCAGAGCAATCCAGGTTCTTCAACTCCAGCCCCT
  GGTGCAGCCCAGCTCAGCAGCAGACTTTGCAAGGCCTTGTATTCTTTTCAAGCCAGGCAAGATGATGAGT
  TGAATTTGGAAAAGGGTGACATTGTGATTATACACGAGAAAAAAGAAGGAGGATGGTGGTTTGGATCTTT
  GAATGGGAAAAAAGGCCATTTTCCTGCCGCTTATGTGGAGGAGTTACCTTCAAATGCTGGCAACACAGCT
  ACAAAGGCATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001171631
• ORF Size: 1692 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001171631.1, NP_001165102.1
• RefSeq Size: 2819
• RefSeq ORF: 1692
• Locus ID: 115677
• Gene Summary: Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production. [supplied by OMIM, Apr 2004]
  Transcript Variant: This variant (4) has additional 5' UTR exons and an internal coding exon, as compared to variant 2. The resulting isoform (4) is the longest, and has an additional segment in the middle region, as compared to isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.