BCAR1 (NM_001170720) Human Untagged Clone
CAT#: SC329095
BCAR1 (untagged)-Human breast cancer anti-estrogen resistance 1 (BCAR1) transcript variant 8
"NM_001170720" in other vectors (4)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | BCAR1 |
Synonyms | CAS; CAS1; CASS1; CRKAS; P130Cas |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_001170720, the custom clone sequence may differ by one or more nucleotides
ATGCAGGGGAAGAACGTGCTGGCCAAAGCGCTCTATGACAATGTGGCCGAGTCCCCGGAT GAGCTCTCCTTCCGCAAGGGTGACATCATGACGGTGCTGGAGCAGGACACGCAGGGCCTG GACGGCTGGTGGCTCTGCTCGCTGCATGGGCGCCAGGGCATCGTGCCTGGGAACCGCCTC AAGATCTTGGTGGTGGTGCCCACCCGCGTGGGGCAGGGCTATGTATACGAGGCCGCCCAG CCGGAGCAGGACGAGTACGACATCCCGCGACACCTGCTGGCCCCGGGGCCACAGGACATC TATGATGTGCCCCCGGTTCGGGGGCTGCTTCCCAGCCAGTATGGCCAGGAGGTGTATGAC ACACCCCCCATGGCTGTCAAGGGTCCCAATGGCCGAGACCCGTTGCTGGAGGTGTATGAC GTGCCCCCCAGTGTGGAGAAGGGCCTGCCACCGTCCAACCACCACGCAGTCTACGACGTT CCTCCATCGGTGAGCAAGGATGTGCCCGATGGCCCACTGCTGCGTGAGGAGACCTACGAT GTGCCCCCCGCCTTCGCCAAGGCCAAGCCCTTTGACCCGGCCCGCACCCCACTGGTACTG GCTGCGCCCCCTCCAGACTCCCCGCCGGCCGAGGACGTGTATGACGTGCCGCCCCCGGCT CCTGACCTCTACGACGTGCCCCCTGGCTTGCGGCGGCCTGGCCCGGGCACCCTGTACGAT GTGCCCCGTGAACGGGTGCTTCCTCCTGAGGTGGCTGATGGTGGCGTGGTCGACAGTGGT GTGTATGCGGTGCCTCCCCCAGCTGAACGTGAAGCCCCGGCAGAGGGCAAGCGCCTGTCG GCCTCCAGCACCGGCAGCACACGCAGCAGCCAGTCTGCGTCCTCCTTGGAGGTGGCAGGG CCGGGCCGGGAACCCCTGGAGCTGGAAGTTGCTGTGGAGGCCCTGGCACGGCTGCAGCAG GGTGTGAGCGCCACCGTTGCCCACCTTCTGGACCTGGCAGGCAGCGCCGGTGCGACTGGG AGCTGGCGTAGCCCCTCTGAGCCACAGGAGCCGCTGGTGCAGGACCTGCAGGCTGCTGTG GCCGCTGTCCAGAGTGCCGTCCACGAGCTGTTGGAGTTTGCCCGCAGCGCGGTGGGCAAT GCTGCCCACACATCTGACCGTGCCCTGCATGCCAAGCTTAGCCGGCAGCTGCAGAAGATG GAGGACGTGCACCAGACGCTGGTGGCACATGGTCAGGCCCTCGACGCTGGCCGGGGAGGC TCTGGAGCCACCCTTGAGGACCTGGACCGGCTGGTGGCCTGCTCGCGGGCTGTGCCCGAG GACGCCAAGCAGCTGGCCTCCTTCCTGCACGGCAATGCCTCACTGCTCTTCAGACGGACC AAGGCCACTGCCCCGGGGCCTGAGGGGGGTGGCACCCTGCACCCCAACCCCACTGACAAG ACCAGCAGCATCCAGTCACGACCCCTGCCCTCACCCCCTAAGTTCACCTCCCAGGACTCG CCAGATGGGCAGTACGAGAACAGCGAGGGGGGCTGGATGGAGGACTATGACTACGTCCAC CTACAGGGGAAGGAGGAGTTTGAGAAGACCCAGAAGGAGCTGCTGGAAAAGGGCAGCATC ACGCGGCAGGGCAAGAGCCAGCTGGAGTTGCAGCAGCTGAAGCAGTTTGAACGACTGGAA CAGGAGGTGTCACGGCCCATAGACCACGACCTGGCCAACTGGACGCCAGCCCAACCCCTG GCCCCGGGGCGAACAGGCGGCCTGGGGCCCTCGGACCGGCAGCTGCTGCTCTTCTACCTG GAGCAGTGTGAGGCCAACCTGACCACACTGACCAACGCCGTGGACGCCTTCTTTACCGCC GTGGCCACCAACCAGCCGCCCAAGATCTTTGTGGCGCACAGCAAGTTCGTCATCCTCAGC GCCCACAAGCTGGTGTTCATCGGGGACACACTGTCACGGCAGGCCAAGGCTGCTGACGTG CGCAGCCAGGTGACCCACTACAGCAACCTGCTGTGCGACCTCCTGCGCGGCATCGTGGCC ACCACCAAGGCCGCTGCCTTGCAGTACCCATCGCCTTCCGCGGCCCAGGACATGGTGGAG AGGGTCAAGGAGCTGGGCCACAGCACCCAGCAGTTCCGCCGCGTCCTAGGCCAGCTGGCA GCCGCCTGA |
Restriction Sites | Please inquire |
ACCN | NM_001170720 |
ORF Size | 2169 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Reference Data | |
RefSeq | NM_001170720.1, NP_001164191.1 |
RefSeq Size | 2943 |
RefSeq ORF | 2169 |
Locus ID | 9564 |
Protein Families | Druggable Genome |
Protein Pathways | Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton |
Gene Summary | The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017] Transcript Variant: This variant (8) has an alternate internal sequence, as compared to variant 1. The resulting isoform (8) is shorter and has a different N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC230457 | BCAR1 (Myc-DDK-tagged)-Human breast cancer anti-estrogen resistance 1 (BCAR1), transcript variant 8 |
USD 800.00 |
|
RG230457 | BCAR1 (GFP-tagged) - Human breast cancer anti-estrogen resistance 1 (BCAR1), transcript variant 8 |
USD 880.00 |
|
RC230457L3 | Lenti-ORF clone of BCAR1 (Myc-DDK-tagged)-Human breast cancer anti-estrogen resistance 1 (BCAR1), transcript variant 8 |
USD 1,000.00 |
|
RC230457L4 | Lenti-ORF clone of BCAR1 (mGFP-tagged)-Human breast cancer anti-estrogen resistance 1 (BCAR1), transcript variant 8 |
USD 1,000.00 |
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