NOX5 (NM_001184780) Human Untagged Clone

CAT#: SC329101

NOX5 (untagged)-Human NADPH oxidase EF-hand calcium binding domain 5 (NOX5) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOX5
• Synonyms: MGC149776; MGC149777
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001184780, the custom clone sequence may differ by one or more nucleotides
  ATGGCCTTCGTCTGTGCCGGCTTATCCGACACCATGAGTGCCGAGGAGGATGCCAGGTGG
  CTCCGGTGGGTGACTCAGCAGTTTAAGACCATTGCAGGAGAAGATGGGGAGATCAGCCTG
  CAAGAATTCAAAGCAGCTCTGCATGTGAAAGAGTCCTTCTTTGCAGAGCGATTCTTTGCC
  CTATTTGACTCCGATAGAAGTGGCACCATCACCCTCCAGGAGCTGCAGGAGGCACTGACC
  CTGCTCATCCATGGCAGCCCCATGGACAAACTCAAATTCCTCTTCCAGGTGTATGACATC
  GATGGCAGTGGCTCCATTGACCCGGATGAGCTGCGCACTGTGCTGCAGTCGTGTCTGCGC
  GAGAGCGCCATCTCGCTGCCTGACGAGAAGCTGGACCAGCTGACGCTGGCGCTCTTCGAA
  TCGGCCGACGCGGACGGCAACGGGGCCATCACCTTCGAGGAGCTCCGGGACGAGCTGCAG
  CGCTTCCCCGGAGTCATGGAGAACCTGACCATCAGCGCTGCCCACTGGCTGACGGCCCCC
  GCCCCCCGCCCACGCCCGCGCCGGCCGCGCCAGCTGACCCGCGCCTACTGGCACAACCAC
  CGCAGCCAGCTGTTCTGCCTGGCCACCTATGCAGGCCTCCACGTGCTGCTCTTCGGGCTG
  GCGGCCAGCGCGCACCGGGACCTCGGCGCCAGCGTCATGGTGGCCAAGGGCTGCGGCCAG
  TGCCTCAACTTCGACTGCAGCTTCATCGCGGTGCTGATGCTCAGACGCTGCCTCACCTGG
  CTGCGGGCCACGTGGCTGGCTCAAGTCCTACCACTGGACCAGAACATCCAGTTCCACCAG
  CTTATGGGCTACGTGGTAGTGGGGCTGTCCCTCGTGCACACCGTGGCTCACACTGTGAAC
  TTTGTACTCCAGGCTCAGGCGGAGGCCAGCCCTTTCCAGTTCTGGGAGCTGCTGCTCACC
  ACGAGGCCTGGCATTGGCTGGGTACACGGTTCGGCCTCCCCGACAGGTGTCGCTCTGCTG
  CTGCTGCTCCTCCTCATGTTCATCTGCTCCAGTTCCTGCATCCGCAGGAGTGGCCACTTT
  GAGGTGTTCTATTGGACTCACCTGTCCTACCTCCTCGTGTGGCTTCTGCTCATCTTTCAT
  GGGCCCAACTTCTGGAAGTGGCTGCTGGTGCCTGGAATCTTGTTTTTCCTGGAGAAGGCC
  ATCGGACTGGCAGTGTCCCGCATGGCAGCCGTGTGCATCATGGAAGTCAACCTCCTCCCC
  TCCAAGGTCACTCATCTCCTCATCAAGCGGCCCCCTTTTTTTCACTATAGACCTGGTGAC
  TACTTGTATCTGAACATCCCCACCATTGCTCGCTATGAGTGGCACCCCTTCACCATCAGC
  AGTGCTCCTGAGCAGAAAGACACTATCTGGCTGCACATTCGGTCCCAAGGCCAGTGGACA
  AACAGGCTGTATGAGTCCTTCAAGGCATCAGACCCACTGGGCCGTGGTTCTAAGAGGCTG
  TCGAGGAGTGTGACAATGAGAAAGAGTCAAAGGTCGTCCAAGGGCTCTGAGATACTTTTG
  GAGAAACACAAATTCTGTAACATCAAGTGCTACATCGATGGGCCTTATGGGACCCCCACC
  CGCAGGATCTTTGCCTCTGAGCATGCCGTGCTCATCGGGGCAGGCATCGGCATCACCCCC
  TTTGCTTCCATTCTGCAGAGTATCATGTACAGGCACCAGAAAAGAAAGCATACTTGCCCC
  AGCTGCCAGCACTCCTGGATCGAAGGTGTCCAAGACAACATGAAGCTCCATAAGGTGGAC
  TTTATCTGGATCAACAGAGACCAGCGGTCTTTCGAGTGGTTTGTGAGCCTGCTGACTAAA
  CTGGAGATGGACCAGGCCGAGGAGGCTCAATACGGCCGCTTCCTGGAGCTGCATATGTAC
  ATGACATCTGCACTGGGCAAGAATGACATGAAGGCCATTGGCCTGCAGATGGCCCTTGAC
  CTCCTGGCCAACAAGGAGAAGAAAGACTCCATCACGGGGCTGCAGACGCGCACCCAGCCT
  GGGCGGCCTGACTGGAGCAAGGTGTTCCAGAAAGTGGCTGCTGAGAAGAAGGGCAAGGTG
  CAGGTCTTCTTCTGTGGCTCCCCAGCTCTGGCCAAGGTGCTGAAGGGCCATTGTGAGAAG
  TTCGGCTTCAGATTTTTCCAAGAGAATTTCTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001184780
• ORF Size: 2193 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001184780.1, NP_001171709.1
• RefSeq Size: 2852
• RefSeq ORF: 2193
• Locus ID: 79400
• Protein Families: Ion Channels: Other, Transmembrane
• Gene Summary: This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
  Transcript Variant: This variant (3, alternately referred to as v6) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1.