LDB3 (NM_001171610) Human Untagged Clone

CAT#: SC329103

LDB3 (untagged)-Human LIM domain binding 3 (LDB3) transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LDB3
• Synonyms: CMD1C; CMH24; CMPD3; CYPHER; LDB3Z1; LDB3Z4; LVNC3; MFM4; ORACLE; PDLIM6; ZASP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001171610, the custom clone sequence may differ by one or more nucleotides
  ATGTCTTACAGTGTGACCCTGACTGGGCCCGGGCCCTGGGGCTTCCGTCTGCAGGGGGGC
  AAGGACTTCAACATGCCCCTCACTATCTCCCGGATCACACCAGGCAGCAAGGCAGCCCAG
  TCCCAGCTCAGCCAGGGTGACCTCGTGGTGGCCATTGACGGCGTCAACACAGACACCATG
  ACCCACCTGGAAGCCCAGAACAAGATCAAGTCTGCCAGCTACAACTTGAGCCTCACCCTG
  CAGAAATCAAAGCGTCCCATTCCCATCTCCACGACAGCACCTCCAGTCCAGACCCCTCTG
  CCGGTGATCCCTCACCAGAAGGACCCCGCTCTGGACACGAACGGCAGCCTGGTGGCACCC
  AGCCCCAGCCCTGAGGCGAGGGCCAGCCCAGGCACCCCAGGCACCCCGGAGCTCAGGCCC
  ACCTTTAGCCCTGCCTTCTCCCGGCCCTCCGCCTTCTCCTCACTCGCCGAGGCCTCTGAC
  CCTGGCCCTCCGCGGGCCAGCCTGAGGGCCAAGACCAGCCCAGAGGGGGCCCGGGACCTA
  CTCGGCCCAAAAGCCCTGCCGGGCTCGAGCCAGCCGAGGCAATATAACAACCCCATTGGC
  CTGTACTCGGCAGAGACCCTGAGGGAGATGGCTCAGATGTACCAGATGAGCCTCCGAGGG
  AAGGCCTCGGGTGTCGGACTCCCAGGAGGCGCCGACTACCAGGAACGCTTCAACCCCAGT
  GCCCTGAAGGACTCGGCCCTGTCCACCCACAAGCCCATCGAGGTGAAGGGGCTGGGCGGC
  AAGGCCACCATCATCCATGCGCAGTACAACACGCCCATCAGCATGTATTCCCAGGATGCC
  ATCATGGATGCCATCGCTGGGCAGGCCCAAGCCCAAGGCAGTGACTTCAGTGGGAGCCTC
  CCTATTAAGGACCTTGCCGTAGACAGCGCCTCTCCCGTCTACCAGGCTGTGATTAAGAGC
  CAGAACAAGCCAGAAGATGAGGCTGACGAGTGGGCACGCCGTTCCTCCAACCTGCAGTCT
  CGCTCCTTCCGCATCCTGGCCCAGATGACGGGGACAGAATTCATGCAAGACCCTGATGAA
  GAAGCTCTGCGAAGGTCAAGGCCCCAGGCCTCTTCCTACAGCCCCGCAGTGGCCGCCTCT
  TCAGCACCTGCCACCCACACCAGCTACAGTGAGGGCCCCGCCGCCCCTGCACCCAAGCCC
  CGGGTTGTCACCACTGCCAGCATCCGGCCTTCTGTCTACCAGCCAGTGCCTGCATCTACC
  TACAGCCCGTCCCCAGGGGCCAATTACAGTCCCACTCCCTACACCCCCTCCCCTGCCCCT
  GCCTACACCCCCTCCCCTGCCCCTGCCTACACCCCCTCACCTGTCCCCACCTACACTCCA
  TCCCCAGCACCAGCCTATACCCCCTCACCTGCCCCCAACTATAACCCTGCACCCTCGGTG
  GCCTACAGCGGGGGCCCTGCGGAGCCTGCCAGCCGTCCACCCTGGGTGACAGATGATAGC
  TTCTCCCAGAAGTTTGCCCCGGGCAAGAGCACCACCTCCATCAGCAAGCAGACCCTGCCC
  CGGGGAGGCCCAGCCTACACCCCAGCGGGTCCTCAGGTGCCACCACTTGCCAGGGGGACC
  GTCCAGAGGGCTGAGCGATTCCCAGCCAGCAGCCGGACTCCACTCTGCGGTCACTGCAAC
  AATGTCATCCGGGGCCCATTTCTGGTAGCCATGGGCCGTTCTTGGCACCCTGAAGAGTTC
  ACCTGTGCCTACTGCAAGACTTCCCTGGCAGATGTGTGCTTTGTGGAAGAGCAGAACAAC
  GTTTACTGTGAGCGATGTTATGAGCAATTCTTTGCCCCGCTGTGTGCCAAGTGCAACACC
  AAAATTATGGGGGAAGTAATGCATGCCTTGAGACAGACATGGCACACCACCTGCTTCGTC
  TGTGCGGCCTGCAAGAAGCCTTTTGGGAACAGCCTCTTCCACATGGAAGACGGGGAGCCC
  TACTGCGAGAAAGACTACATCAATCTGTTCAGCACCAAGTGCCATGGCTGCGATTTCCCC
  GTGGAGGCTGGCGACAAGTTTATCGAAGCCCTGGGCCACACTTGGCACGACACCTGCTTC
  ATTTGCGCAGTCTGCCATGTGAATCTGGAGGGGCAGCCGTTCTACTCCAAGAAGGACAGA
  CCCCTGTGCAAGAAGCACGCACACACCATCAACTTGTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001171610
• ORF Size: 2199 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001171610.1, NP_001165081.1
• RefSeq Size: 5436
• RefSeq ORF: 2199
• Locus ID: 11155
• Gene Summary: This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq, Jan 2010]
  Transcript Variant: This variant (5) has multiple differences in the coding region, compared to variant 1. The encoded isoform (5) is longer than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.